Intro to immunology medium

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Questions and Answers

What is the main function of phagocytes?

  • To secrete cytokines
  • To assist T cells in recognizing antigens
  • To produce antibodies
  • To phagocytose microbes (correct)

Which type of immune response involves a lag time before becoming effective?

  • Humoral immunity
  • Adaptive immunity (correct)
  • Innate immunity
  • Cell-mediated immunity

Where do T cells and antigen-presenting cells derive from?

  • Hematopoietic stem cells in bone marrow (correct)
  • Hematopoietic stem cells in the spleen
  • Progenitor cells in thymus
  • The liver

Which cells are specifically involved in the production of antibodies?

<p>B cells (A)</p> Signup and view all the answers

What distinguishes adaptive immunity from innate immunity?

<p>Presence of memory and antigen-specific actions (D)</p> Signup and view all the answers

What role do dendritic cells play in the immune response?

<p>They present antigens to T cells (A)</p> Signup and view all the answers

What distinguishes a neutrophil from a macrophage?

<p>Neutrophils are short-lived, while macrophages are long-lived (B)</p> Signup and view all the answers

Which of the following statements about cytokines is true?

<p>They are signaling proteins that mediate immune responses (C)</p> Signup and view all the answers

What is the primary function of the innate immune system?

<p>To initiate a rapid response to a wide range of pathogens (C)</p> Signup and view all the answers

What is the primary role of mast cells in the immune system?

<p>Release of histamines during allergic responses (B)</p> Signup and view all the answers

Which cells are considered lymphocytes in the immune system?

<p>T cells and B cells (C)</p> Signup and view all the answers

Which of the following is NOT a defensive barrier of the innate immune system?

<p>Antibodies (D)</p> Signup and view all the answers

Which cells are primarily involved in the non-specific immune response?

<p>Phagocytes and natural killer cells (C)</p> Signup and view all the answers

What characterizes the adaptive immune system?

<p>It develops immunological memory after exposure to antigens (B)</p> Signup and view all the answers

Which of these components is most closely associated with the detection of pathogens in the innate immune system?

<p>Pattern recognition receptors (PRRs) (B)</p> Signup and view all the answers

What is the primary goal of studying immunology in the context of biomedical sciences?

<p>To apply principles to dental therapy and hygiene (C)</p> Signup and view all the answers

Which option describes one of the main features of innate immunity?

<p>It is the first line of defense against pathogens (A)</p> Signup and view all the answers

Which cell type is associated with the adaptive immune response?

<p>B cells (C)</p> Signup and view all the answers

How does innate immunity differ from adaptive immunity?

<p>Innate immunity responds quickly to pathogens, while adaptive takes longer (C)</p> Signup and view all the answers

Which of the following is an example of a physiological barrier in the innate immune system?

<p>The secretion of mucus in the respiratory tract (A)</p> Signup and view all the answers

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Study Notes

The Immune System

  • The immune system defends the body from foreign substances including pathogens.
  • The immune system consists of cells, chemicals, and processes that protect the body.
  • There are two main types of immunity: innate and adaptive immunity.

Innate Immunity

  • Innate immunity is the body's first line of defense against pathogens.
  • It is non-specific and acts rapidly.
  • Innate immunity does not have immunological memory.
  • It relies on pattern recognition receptors (PRRs) that recognize pathogens.
  • Innate immunity includes four defensive barriers:
    • Physiologic barriers (temperature, pH, chemical mediators)
    • Anatomic barriers (skin, mucous membranes)
    • Endocytic/phagocytic barriers
    • Inflammatory barriers
  • Innate immunity rapidly recruits immune cells to sites of infection and inflammation

Adaptive Immunity

  • The adaptive immune system is antigen-dependent and antigen-specific.
  • Adaptive immunity develops with the help of the innate immune system and has memory.
  • Adaptive immunity enables the body to mount a more rapid and efficient immune response.
  • Requires a lag time for development and action.
  • Recognizes specific non-self antigens and distinguishes them from self antigens.
  • Cells involved:
    • Antigen-specific T cells
    • B cells which differentiate into plasma cells to produce antibodies
  • T cells and antigen-presenting cells (APCs) derive from hematopoietic stem cells in the bone marrow.
  • T cells express unique antigen-binding receptors on their membrane, called T cell receptors.
  • T cells require the action of APCs to recognize specific antigens.
  • Defects in either the innate or adaptive immune system can cause illness or disease.

Cells of the Immune System

  • Phagocytes:
    • Neutrophils: short-lived cells that phagocytose microbes.
    • Macrophages: long-lived cells that phagocytose microbes.
  • Eosinophils
  • Dendritic cells
  • Mast cells
  • Basophils
  • T cells: lymphocytes
  • Epithelial cells
  • Cytokines: proteins and glycoproteins

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