10 Questions
Which type of twins are more likely to develop the same autoimmune disease if one twin already has it?
Identical twins
What is the main contribution to the inherited risk of most autoimmune diseases?
Multiple gene loci
What is the likelihood of a particular autoimmune disease in people with versus without a particular HLA allele expressed as?
Odds ratio
Which of the following is true about the association between HLA alleles and autoimmune diseases?
HLA alleles increase the risk of developing autoimmune diseases.
Which class of HLA alleles are most commonly associated with autoimmune diseases?
Class II HLA alleles
What is the role of MHC molecules in autoimmune diseases?
MHC molecules control the action of CD4+ T cells.
What is the cause of autoimmune diseases?
Environmental triggers
Which of the following is true about the HLA-B27 allele and ankylosing spondylitis?
The risk of developing ankylosing spondylitis is 90 to 100 times higher in people with the HLA-B27 allele compared to those without it.
Which of the following is true about HLA alleles and diseases?
Different HLA alleles are associated with different diseases.
Which methods are used to identify HLA alleles?
Molecular (DNA-based) typing and serologic (antibody-based) methods.
Test your knowledge on the genetic factors influencing autoimmune diseases with this quiz. Explore the role of MHC genes and the increased risk of developing the same autoimmune disease in twins. Challenge yourself to understand the differences between monozygotic and dizygotic twins in relation to autoimmune diseases.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
