The Essentials of CBC and Hemostasis Testing

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Which method is used for automated cell counting today?

Electrical-Impedance

Light-Scatter

Both Electrical-Impedance and Light-Scatter (correct)

None of the above

Who led the characterization of RBC indices and definitions of anemia?

Maxwell M. Wintrobe

Weisse AB

Max Wintrobe (correct)

Fred HL

What is hematocrit?

The percentage of total blood volume occupied by plasma

The percentage of total blood volume occupied by red blood cells (correct)

The percentage of total blood volume occupied by white blood cells

The percentage of total blood volume occupied by platelets

What does ESR stand for?

Erythrocyte Sedimentation Rate Signup and view all the answers

What does MCV stand for?

Mean Corpuscular (Cell) Volume Signup and view all the answers

What does RDW stand for?

Red Blood Cell Distribution Width Signup and view all the answers

What does MCH stand for?

Mean Corpuscular Hemoglobin Signup and view all the answers

What does MCHC stand for?

Mean Corpuscular Hemoglobin Concentration Signup and view all the answers

What does lymphocytopenia refer to?

Decrease in lymphocytes Signup and view all the answers

What is the most common cause of lymphocytopenia?

AIDS Signup and view all the answers

Which of the following is a component of the complete blood count (CBC)?

Total RBC Count Signup and view all the answers

What is the purpose of the Erythrocyte Sedimentation Rate (ESR) test?

To detect inflammation or infection Signup and view all the answers

What is the significance of reporting leukocyte differential counts as relative percentages?

It helps in identifying specific types of white blood cells Signup and view all the answers

What is the main advantage of reporting leukocyte differential counts as absolute numbers?

It provides a more accurate assessment of the total white blood cell count Signup and view all the answers

Which laboratory diagnostic procedure is used to approach patients with bleeding disorders?

PT Signup and view all the answers

What does MCH stand for in blood indices?

Mean Corpuscular Hemoglobin Signup and view all the answers

What does MCV stand for in blood indices?

Mean Corpuscular Volume Signup and view all the answers

What does MCHC stand for in blood indices?

Mean Corpuscular Hemoglobin Concentration Signup and view all the answers

Which historical figure visualized blood cells using a microscope?

A van Leeuwenhoek Signup and view all the answers

What is the purpose of the Platelet Count test?

To measure the concentration of platelets Signup and view all the answers

Which of the following is true about relative lymphocytosis?

It occurs when there is a higher proportion of lymphocytes among the white blood cells. Signup and view all the answers

What is the normal range for lymphocytes?

20 to 40 1000 to 4750 /mm3 Signup and view all the answers

What is the normal range for eosinophils?

0 to 4 0 to 450/mm3 Signup and view all the answers

What is the normal range for monocytes?

2 to 9 100 to 700 /mm3 Signup and view all the answers

What is the normal range for basophils?

0 to 2 0 to 200 /mm3 Signup and view all the answers

What is the purpose of mixing studies in determining a clotting defect?

To determine the presence of a coagulation factor inhibitor. Signup and view all the answers

Which conditions may be present when the PT result is prolonged and the PTT result is normal?

Liver disease, decreased vitamin K, decreased or defective factor VII, chronic low-grade disseminated intravascular coagulation (DIC), anticoagulation drug (warfarin) therapy Signup and view all the answers

Which conditions may be present when the PT result is normal and the PTT result is prolonged?

Decreased or defective factor VIII, IX, XI, or XII, von Willebrand disease (severe type), presence of lupus anticoagulant, autoantibody against a specific factor (e.g., factor VIII) Signup and view all the answers

What is the purpose of factor-specific testing in diagnosing clotting disorders?

To determine the presence of a coagulation factor inhibitor Signup and view all the answers