The DNA Structure Challenge

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Questions and Answers

In DNA, how is the second strand oriented in relation to the first strand?

  • Parallel
  • Random
  • Perpendicular
  • Antiparallel (correct)

What is the correct name for the base sugar with the phosphate in DNA?

  • Phosphodiester
  • Nucleotide (correct)
  • Nitrogen base
  • Deoxyribose

What is the correct nomenclature for the base bound to the sugar in DNA?

  • Nitrogen base (correct)
  • Phosphodiester
  • Deoxyribose
  • Nucleotide

What is the number of hydrogen bonds formed between adenine and thymine in DNA?

<p>Two (A)</p> Signup and view all the answers

Which nitrogen base pair is easier to denature in DNA?

<p>Adenine and Thymine (D)</p> Signup and view all the answers

Which carbon on the deoxyribose in DNA is usually replaced by a normal hydrogen?

<p>Fifth carbon (D)</p> Signup and view all the answers

What are the two types of nitrogen-containing bases in DNA?

<p>Purines and pyrimidines (D)</p> Signup and view all the answers

How many cyclic structures do purines have in DNA?

<p>Two (C)</p> Signup and view all the answers

How many carbon atoms are in the sugar of DNA?

<p>Five (A)</p> Signup and view all the answers

Which carbon on the deoxyribose in DNA is replaced by a normal hydrogen?

<p>Second carbon (C)</p> Signup and view all the answers

What is the correct nomenclature for the base bound to the sugar in DNA?

<p>Nucleoside (C)</p> Signup and view all the answers

What is the correct name for the base sugar with the phosphate in DNA?

<p>Nucleotide (A)</p> Signup and view all the answers

Which nitrogen base pair is easier to denature in DNA?

<p>Adenine-Thymine (A)</p> Signup and view all the answers

In DNA, how is the second strand oriented in relation to the first strand?

<p>Antiparallel (C)</p> Signup and view all the answers

Which type of bond connects the sugar and phosphate backbones in DNA?

<p>Covalent bond (A)</p> Signup and view all the answers

What is the number of hydrogen bonds formed between adenine and thymine in DNA?

<p>2 (C)</p> Signup and view all the answers

What is the correct name for the base sugar with the phosphate in RNA?

<p>Nucleotide (D)</p> Signup and view all the answers

What is the correct nomenclature for the base bound to the sugar in RNA?

<p>Nucleoside (B)</p> Signup and view all the answers

Which nitrogen base pair is more stable in DNA?

<p>Guanine-Cytosine (D)</p> Signup and view all the answers

Which of the following is a key difference between DNA and RNA?

<p>DNA has deoxyribose sugar, while RNA has ribose sugar (B)</p> Signup and view all the answers

Which type of RNA is the most predominant in each cell for making proteins?

<p>rRNA (A)</p> Signup and view all the answers

How many hydrogen bonds are formed between cytosine and guanine in DNA?

<p>Three (C)</p> Signup and view all the answers

Which nitrogen base is replaced by uracil in RNA?

<p>Thymine (A)</p> Signup and view all the answers

Which type of RNA is responsible for carrying amino acids to the ribosome during protein synthesis?

<p>tRNA (D)</p> Signup and view all the answers

Which type of RNA is involved in the assembly of ribosomes?

<p>rRNA (C)</p> Signup and view all the answers

Which type of RNA is involved in the regulation of gene expression?

<p>microRNA (B)</p> Signup and view all the answers

In DNA, which carbon on the sugar molecule is missing an oxygen atom?

<p>Second carbon (A)</p> Signup and view all the answers

Which type of RNA is responsible for carrying the genetic information from the DNA to the ribosome for protein synthesis?

<p>mRNA (C)</p> Signup and view all the answers

How many hydrogen bonds are formed between adenine and thymine in DNA?

<p>Two (C)</p> Signup and view all the answers

What is the main difference in DNA packaging between prokaryotes and eukaryotes?

<p>Prokaryotes use supercoiling, while eukaryotes use histones (B)</p> Signup and view all the answers

What is the function of supercoiling in DNA packaging?

<p>To shorten the DNA and make it fit into the cell (A)</p> Signup and view all the answers

What happens when a negative supercoil is introduced in DNA?

<p>Tension is introduced and the DNA twists around itself (D)</p> Signup and view all the answers

What happens when a positive supercoil is introduced in DNA?

<p>Tension is introduced and the DNA twists around itself (A)</p> Signup and view all the answers

What is the role of topoisomerases in DNA packaging?

<p>To introduce or remove supercoils in DNA (C)</p> Signup and view all the answers

What is the main difference between topoisomerase I and topoisomerase II?

<p>Topoisomerase I makes a single strand break, while topoisomerase II makes a double strand break (C)</p> Signup and view all the answers

What is the main difference in DNA structure between prokaryotes and eukaryotes?

<p>Prokaryotes have circular DNA, while eukaryotes have linear DNA (C)</p> Signup and view all the answers

What is the main function of coding DNA in prokaryotes?

<p>To make proteins (D)</p> Signup and view all the answers

What is the main function of non-coding DNA in eukaryotes?

<p>Regulatory functions leading to alternative splicing (A)</p> Signup and view all the answers

What is the main advantage of DNA supercoiling in prokaryotes?

<p>Efficient packaging of DNA into a small cell (D)</p> Signup and view all the answers

What is the major way in which DNA is packaged into the cell in prokaryotes?

<p>By using topoisomerases (C)</p> Signup and view all the answers

What are the yellow parts in the picture called?

<p>Histones (C)</p> Signup and view all the answers

How many times does the DNA wrap around the histones in a nucleosome?

<p>Two times (D)</p> Signup and view all the answers

How many proteins are there in an octamer?

<p>Eight (C)</p> Signup and view all the answers

What is the role of histone H1 in DNA packaging?

<p>To attach one nucleosome to the next (B)</p> Signup and view all the answers

What is the main difference in DNA packaging between prokaryotes and eukaryotes?

<p>Prokaryotes use topoisomerases, while eukaryotes use histones and non-histone proteins (C)</p> Signup and view all the answers

What is the correct name for the proteins that make up an octamer?

<p>H2A, H2B, H3, H4 (C)</p> Signup and view all the answers

What is the role of topoisomerases in DNA packaging?

<p>To introduce breaks in the DNA strands (A)</p> Signup and view all the answers

What is the correct nomenclature for the base sugar with the phosphate in DNA?

<p>Deoxyribose (A)</p> Signup and view all the answers

What is the main advantage of DNA supercoiling in prokaryotes?

<p>It allows for efficient DNA packaging (C)</p> Signup and view all the answers

Which structure is responsible for condensing DNA into a solenoid?

<p>Nucleosome (D)</p> Signup and view all the answers

What is the role of histone h one in DNA packaging?

<p>It keeps nucleosomes together (C)</p> Signup and view all the answers

What is the main function of acetylating histones?

<p>To open up DNA for transcription (C)</p> Signup and view all the answers

What is the significance of the positive charge of nucleosomes in DNA packaging?

<p>It pulls the DNA close (D)</p> Signup and view all the answers

What is the function of scaffold proteins in DNA packaging?

<p>To keep loops of solenoids together (D)</p> Signup and view all the answers

How many kilo base pairs of DNA does each loop in the solenoid structure contain?

<p>60 to 100 KB (C)</p> Signup and view all the answers

What is the structure formed when loops of solenoids are organized in a flower-like manner?

<p>Rosetta (A)</p> Signup and view all the answers

Where are the two chromatids of a chromosome kept together?

<p>Centromere (A)</p> Signup and view all the answers

What is the p arm of a chromosome?

<p>The short arm (C)</p> Signup and view all the answers

What is the main difference in chromosome structure between eukaryotes and bacteria?

<p>Eukaryotes have linear chromosomes, while bacteria have circular chromosomes (B)</p> Signup and view all the answers

Which of the following is a correct statement about chromatids?

<p>Chromatids are formed after replication and are attached to each other in the centromere. (C)</p> Signup and view all the answers

What is the main function of introns in DNA?

<p>Introns are non-coding parts of DNA that are removed from the RNA during splicing. (B)</p> Signup and view all the answers

What is the relationship between genes and chromatids?

<p>Genes are located on chromatids and lie next to each other. (C)</p> Signup and view all the answers

What is the main function of exons in DNA?

<p>Exons are parts of DNA that code for proteins. (B)</p> Signup and view all the answers

What is the process by which introns are removed from RNA called?

<p>Splicing (B)</p> Signup and view all the answers

In the picture, are exons larger or smaller than introns?

<p>Exons are larger than introns in the picture. (A)</p> Signup and view all the answers

In real life, are exons larger or smaller than introns?

<p>Introns are usually much bigger than exons in real life. (B)</p> Signup and view all the answers

What is the main difference between the chromatids in the picture?

<p>The chromatids in the picture are not identical because they contain different genes. (A)</p> Signup and view all the answers

What is the main difference between the chromatids in real life?

<p>The chromatids in real life are identical because they are formed from replication. (A)</p> Signup and view all the answers

Which of the following is a correct statement about DNA packaging in real life?

<p>Introns are usually much bigger than exons in DNA packaging. (A)</p> Signup and view all the answers

Which structure is visible under the microscope when DNA is condensed during cell division?

<p>Chromosomes (A)</p> Signup and view all the answers

What is the purpose of condensing DNA during cell division?

<p>To make it more visible under the microscope (B)</p> Signup and view all the answers

Which part of the chromosome can be different in length between the P arm and the Q arm?

<p>Chromatids (A)</p> Signup and view all the answers

Where are the different alleles located within a chromosome?

<p>On different chromatids (C)</p> Signup and view all the answers

What can be exchanged during crossing over of chromosomes?

<p>Information between chromosomes (B)</p> Signup and view all the answers

Are chromosomes necessarily identical?

<p>No (C)</p> Signup and view all the answers

How many copies of chromosome one does an individual have?

<p>Two (D)</p> Signup and view all the answers

Where are the different alleles located within a chromosome?

<p>On different chromatids (C)</p> Signup and view all the answers

What is the process called when introns are removed from RNA?

<p>Splicing (B)</p> Signup and view all the answers

Are the two chromatids within one chromosome identical?

<p>Yes (C)</p> Signup and view all the answers

Which part of the nucleus is typically occupied by nontranscribed parts of the DNA?

<p>The nuclear membrane (A)</p> Signup and view all the answers

What is the behavior of mitochondrial DNA similar to?

<p>Bacterial DNA (C)</p> Signup and view all the answers

How many copies of DNA does each mitochondrion typically have?

<p>Five to ten (C)</p> Signup and view all the answers

What is the main function of mitochondria in a cell?

<p>Energy production (C)</p> Signup and view all the answers

How does DNA packaging differ between prokaryotes and eukaryotes?

<p>Prokaryotes have circular DNA, while eukaryotes have linear DNA (B)</p> Signup and view all the answers

Where are the nontranscribed parts of the DNA typically located within the nucleus?

<p>The nuclear membrane (A)</p> Signup and view all the answers

What is the structure of mitochondrial DNA?

<p>Circular (D)</p> Signup and view all the answers

What is the main difference between mitochondrial DNA and nuclear DNA?

<p>Mitochondrial DNA is circular, while nuclear DNA is linear (B)</p> Signup and view all the answers

Where are the transcribed parts of the DNA typically located within the nucleus?

<p>The center (A)</p> Signup and view all the answers

How does the behavior of mitochondrial DNA compare to bacterial DNA?

<p>Mitochondrial DNA is circular, while bacterial DNA is linear (B)</p> Signup and view all the answers

What is the total size of mitochondrial DNA?

<p>17 kilobases (C)</p> Signup and view all the answers

Which of the following is true about mitochondrial DNA coding?

<p>It codes for rRNA, tRNAs, and some proteins (C)</p> Signup and view all the answers

How does mitochondrial DNA compare to nuclear DNA in terms of size?

<p>Mitochondrial DNA is much smaller than nuclear DNA (D)</p> Signup and view all the answers

How many mitochondria can be found in a single cell?

<p>A few hundred to several thousand up to 200,000 (A)</p> Signup and view all the answers

What is the main difference between nuclear DNA and mitochondrial DNA?

<p>Nuclear DNA is predominantly coding DNA, while mitochondrial DNA has more non-coding DNA (D)</p> Signup and view all the answers

What is the function of histone modifications?

<p>To determine the structure of DNA (A)</p> Signup and view all the answers

What happens when histones are acetylated?

<p>Histones lose their positive charge and DNA becomes more open (A)</p> Signup and view all the answers

Why can we only see chromosomes during cell division?

<p>The DNA in interphase cells is not completely condensed (D)</p> Signup and view all the answers

How many chromosomes do humans have?

<p>46 (D)</p> Signup and view all the answers

What is the role of topoisomerases in DNA packaging?

<p>To relieve supercoiling and prevent DNA tangling (A)</p> Signup and view all the answers

Which enzyme is responsible for proofreading and cutting out wrongly attached bases during DNA replication?

<p>Exonuclease (B)</p> Signup and view all the answers

What is the function of the origin of replication in DNA replication?

<p>To provide a starting point for the polymerase (D)</p> Signup and view all the answers

What type of base sequence is easier to open up during DNA replication?

<p>AT-rich sequence (B)</p> Signup and view all the answers

What is the role of single strand binding proteins in DNA replication?

<p>To stabilize single stranded DNA (D)</p> Signup and view all the answers

Which enzyme is responsible for unzipping the DNA strands during DNA replication?

<p>Helicase (A)</p> Signup and view all the answers

What is the function of RNA primers in DNA replication?

<p>To provide a free three prime site for DNA polymerase (D)</p> Signup and view all the answers

What is the direction of DNA synthesis during DNA replication?

<p>From five prime to three prime (A)</p> Signup and view all the answers

What is the structure that forms when DNA strands are separated during DNA replication?

<p>Fork (A)</p> Signup and view all the answers

Which enzyme is responsible for elongating the DNA strands during DNA replication?

<p>Polymerase (A)</p> Signup and view all the answers

What is the function of the proofreading activity of DNA polymerase?

<p>To cut out wrongly attached bases (B)</p> Signup and view all the answers

Which of the following is the correct definition of a nucleotide?

<p>A sugar and a base attached to each other (C)</p> Signup and view all the answers

What is a nucleosome?

<p>A combination of histones and DNA wrapped around it (C)</p> Signup and view all the answers

When is DNA fully packed into chromosomes?

<p>During the metaphase (A)</p> Signup and view all the answers

What is the main purpose of transcription?

<p>To make mRNA (D)</p> Signup and view all the answers

When does replication of DNA occur?

<p>During the interface phase (B)</p> Signup and view all the answers

What happens to DNA during the metaphase of cell division?

<p>It is fully packed into chromosomes (D)</p> Signup and view all the answers

What is the process of DNA making up chromatids and then chromosomes called?

<p>Condensation (A)</p> Signup and view all the answers

What is the role of histones in DNA packaging?

<p>To condense DNA into chromosomes (B)</p> Signup and view all the answers

When is DNA fully accessible for transcription?

<p>During the interface phase (A)</p> Signup and view all the answers

What is the function of replication in DNA?

<p>To create a copy of DNA (A)</p> Signup and view all the answers

What is the main function of DNA polymerase during DNA replication?

<p>To read the template strand from 5' to 3' and synthesize new DNA in the 3' to 5' direction (C)</p> Signup and view all the answers

What is the difference between chromatin and nucleosome?

<p>Chromatin refers to the whole structure of DNA combined with its proteins, while a nucleosome is a part of the chromatin (D)</p> Signup and view all the answers

What is the correct direction of DNA synthesis during replication?

<p>5' to 3' (A)</p> Signup and view all the answers

What is the main difference between semiconservative and conservative DNA replication?

<p>In semiconservative replication, each strand is the template for a new complementary strand, while in conservative replication, the original strands remain together and the new strands remain together (A)</p> Signup and view all the answers

What is the role of DNA polymerase in DNA replication?

<p>To synthesize new DNA strands by adding nucleotides in a complementary manner (C)</p> Signup and view all the answers

What is the function of histone proteins in chromatin?

<p>To help package and organize DNA into a compact structure (D)</p> Signup and view all the answers

What is the correct direction of DNA synthesis during replication?

<p>5' to 3' (A)</p> Signup and view all the answers

What is the function of DNA polymerase in DNA replication?

<p>To synthesize new DNA strands by adding nucleotides in a complementary manner (B)</p> Signup and view all the answers

What is the difference between chromatin and nucleosome?

<p>Chromatin refers to the whole structure of DNA combined with its proteins, while a nucleosome is a part of the chromatin (A)</p> Signup and view all the answers

What is the main difference between semiconservative and conservative DNA replication?

<p>In semiconservative replication, each strand is the template for a new complementary strand, while in conservative replication, the original strands remain together and the new strands remain together (D)</p> Signup and view all the answers

Which enzyme attaches to the helicase during DNA replication in prokaryotes and is called a primo zone?

<p>DNA primase (D)</p> Signup and view all the answers

In which direction does the helicase move during DNA replication in the leading strand?

<p>Left to right (D)</p> Signup and view all the answers

Which enzyme synthesizes the DNA in the 5' to 3' direction during DNA replication?

<p>DNA polymerase (A)</p> Signup and view all the answers

In which direction does the polymerase move during DNA replication in the leading strand?

<p>Left to right (D)</p> Signup and view all the answers

In which direction does the helicase move during DNA replication in the lagging strand?

<p>Left to right (C)</p> Signup and view all the answers

In which direction does the polymerase move during DNA replication in the lagging strand?

<p>Right to left (C)</p> Signup and view all the answers

What is the term used to describe the combination of a short stretch of RNA with the DNA during DNA replication?

<p>Okazaki fragment (D)</p> Signup and view all the answers

Which DNA polymerase is responsible for removing the RNA primer and filling the gap?

<p>Polymerase one (C)</p> Signup and view all the answers

What is the name of the clamp that helps keep the DNA polymerase attached to the DNA?

<p>PCNA (B)</p> Signup and view all the answers

Which DNA polymerase is the major chromosome replicating enzyme?

<p>Polymerase three (A)</p> Signup and view all the answers

What is the enzyme responsible for closing the gaps between Okazaki fragments?

<p>Ligase (B)</p> Signup and view all the answers

Which DNA polymerase is involved in DNA repair?

<p>Polymerase two (B)</p> Signup and view all the answers

What is the activity of polymerase one that allows it to remove the RNA primer and DNA?

<p>Exonuclease activity (C)</p> Signup and view all the answers

What is the direction of replication that determines whether a strand is a leading or lagging strand?

<p>Left to right (D)</p> Signup and view all the answers

Which enzyme is responsible for removing the RNA primer and replacing it with DNA?

<p>DNA polymerase one (D)</p> Signup and view all the answers

What is the function of topoisomerases in DNA replication?

<p>To remove positive supercoils (D)</p> Signup and view all the answers

What is the role of the DNA ligase in DNA replication?

<p>To join Okazaki fragments (A)</p> Signup and view all the answers

What is the main difference between the leading and lagging strands in DNA replication?

<p>The leading strand is synthesized continuously, while the lagging strand is synthesized discontinuously (D)</p> Signup and view all the answers

What is the function of the helicase in DNA replication?

<p>To unwind the DNA (A)</p> Signup and view all the answers

What is the role of the primase in DNA replication?

<p>To synthesize the RNA primer (D)</p> Signup and view all the answers

What is the main difference between prokaryotic and eukaryotic DNA replication?

<p>Prokaryotic DNA replication is unidirectional, while eukaryotic DNA replication is bidirectional (B)</p> Signup and view all the answers

Which model describes the replication of nucleosomes in eukaryotes?

<p>Semiconservative model (B)</p> Signup and view all the answers

What happens to the nucleosome during replication in eukaryotes?

<p>The nucleosome is split over two chromosomes (A)</p> Signup and view all the answers

Which enzyme is responsible for removing the primer in eukaryotic DNA replication?

<p>RNase (C)</p> Signup and view all the answers

What is the function of single strand binding proteins in DNA replication?

<p>To stabilize the single stranded DNA (B)</p> Signup and view all the answers

Which protein acts as a sliding clamp in DNA replication?

<p>PCNA (C)</p> Signup and view all the answers

What is the main difference between DNA and RNA?

<p>DNA has deoxyribose sugar while RNA has ribose sugar (B)</p> Signup and view all the answers

Which type of RNA is involved in the regulation of gene expression?

<p>miRNA (A)</p> Signup and view all the answers

What is the role of DNA polymerase in DNA replication?

<p>To synthesize new DNA strands (B)</p> Signup and view all the answers

How many hydrogen bonds are formed between cytosine and guanine in DNA?

<p>Two (D)</p> Signup and view all the answers

Which nucleotides are used by the polymerase to build DNA during replication?

<p>ATP, GTP, TTP, CTP (B)</p> Signup and view all the answers

What is the function of an RNA primer in DNA replication?

<p>To initiate DNA synthesis (C)</p> Signup and view all the answers

What is the role of the Tata box in DNA replication?

<p>To regulate transcription (C)</p> Signup and view all the answers

Which polymerases are present in prokaryotes but not in eukaryotes?

<p>Polymerase III and Polymerase I (B)</p> Signup and view all the answers

What is the function of DNA primase?

<p>To synthesize DNA primers (A)</p> Signup and view all the answers

What is the main difference between DNA replication and transcription?

<p>The direction of synthesis (B)</p> Signup and view all the answers

Which type of RNA is involved in the assembly of ribosomes?

<p>rRNA (C)</p> Signup and view all the answers

What is the origin of replication in DNA replication?

<p>The region where DNA unwinds (B)</p> Signup and view all the answers

What is the function of histone proteins in chromatin?

<p>To compact and organize DNA (D)</p> Signup and view all the answers

What is the main difference between polymerase III and polymerase I?

<p>Their function in DNA replication (B)</p> Signup and view all the answers

Which one of the following statements about DNA replication is NOT true?

<p>In eukaryotes, the DNA is located in the cytoplasm. (B)</p> Signup and view all the answers

What is the main difference between the replication of DNA in prokaryotes and eukaryotes?

<p>Prokaryotes have one type of polymerase while eukaryotes have multiple types. (C)</p> Signup and view all the answers

Which of the following statements about mitochondrial DNA is true?

<p>Mitochondrial DNA can undergo mutations. (B)</p> Signup and view all the answers

What is the main factor that determines whether a woman has the same mitochondrial DNA as her great great great grandmother?

<p>The transmission of mitochondrial DNA from mother to child. (A)</p> Signup and view all the answers

Which of the following is NOT a potential cause of changes in DNA over time?

<p>The number of replication falls. (B)</p> Signup and view all the answers

What is the main difference between prokaryotes and eukaryotes in terms of DNA replication?

<p>Prokaryotes have their DNA in the cytoplasm. (C)</p> Signup and view all the answers

Which of the following is NOT a difference between prokaryotes and eukaryotes in terms of DNA replication?

<p>Eukaryotes have more proteins involved in replication than prokaryotes. (B)</p> Signup and view all the answers

Which of the following is NOT a potential cause of differences in mitochondrial DNA between individuals?

<p>The number of replication falls in mitochondrial DNA. (B)</p> Signup and view all the answers

What is the main difference between the replication of DNA in prokaryotes and eukaryotes in terms of origins of replication?

<p>Prokaryotes have multiple origins of replication while eukaryotes have only one. (D)</p> Signup and view all the answers

Which of the following is NOT a potential cause of changes in mitochondrial DNA over time?

<p>The number of replication falls in mitochondrial DNA. (D)</p> Signup and view all the answers

Which enzyme removes the RNA primers in prokaryotes during DNA replication?

<p>DNA polymerase one (A)</p> Signup and view all the answers

Which enzyme removes the RNA primers in eukaryotes during DNA replication?

<p>RNase (C)</p> Signup and view all the answers

Which type of topoisomerase is predominantly active in DNA unwinding?

<p>Topoisomerase two (A)</p> Signup and view all the answers

Is PCNA a type of single strand binding protein?

<p>No (C)</p> Signup and view all the answers

Why do we need Okazaki fragments during DNA replication?

<p>To synthesize the lagging strand (A)</p> Signup and view all the answers

Can DNA ligase and DNA polymerase one act while DNA is being synthesized?

<p>Yes (B)</p> Signup and view all the answers

Can DNA ligase and DNA polymerase one act while Okazaki fragments are being made?

<p>Yes (C)</p> Signup and view all the answers

Does DNA polymerase one remove the RNA primers during DNA replication?

<p>Yes (C)</p> Signup and view all the answers

Does DNA polymerase two remove the RNA primers during DNA replication?

<p>No (B)</p> Signup and view all the answers

Does DNA polymerase three remove the RNA primers during DNA replication?

<p>No (D)</p> Signup and view all the answers

What is the function of the okazaki fragments during DNA replication?

<p>To provide a template for the synthesis of a new DNA strand (B)</p> Signup and view all the answers

Which direction does the axonuclease work in?

<p>Both 5' to 3' and 3' to 5' (A)</p> Signup and view all the answers

What is the main function of the primosome complex on the lagging strand during DNA replication?

<p>To synthesize RNA primers (D)</p> Signup and view all the answers

Why does DNA shorten over time after multiple replications in somatic cells?

<p>Due to the end replication problem (D)</p> Signup and view all the answers

What is the function of telomerase in dealing with the end replication problem?

<p>To lengthen telomeres at the ends of chromosomes (C)</p> Signup and view all the answers

What is an okazaki fragment composed of?

<p>RNA primer and DNA (D)</p> Signup and view all the answers

What is the main difference in the number of replication forks between prokaryotes and eukaryotes?

<p>Eukaryotes have more replication forks than prokaryotes (B)</p> Signup and view all the answers

What is the main function of DNA primase during DNA replication?

<p>To synthesize RNA primers (D)</p> Signup and view all the answers

What is the direction of DNA synthesis during DNA replication?

<p>5' to 3' (D)</p> Signup and view all the answers

What is the main function of the exonuclease activity of DNA polymerase?

<p>To proofread and correct errors in DNA synthesis (A)</p> Signup and view all the answers

Which enzyme is responsible for synthesizing DNA during replication?

<p>DNA polymerase three (C)</p> Signup and view all the answers

Which nucleotide is used to pair with adenine (A) during DNA replication?

<p>Thymine (T) (A)</p> Signup and view all the answers

Which type of supercoiling occurs when a turn is added to the DNA?

<p>Positive supercoil (B)</p> Signup and view all the answers

What is the main function of DNA polymerase one during DNA replication?

<p>Replacing the RNA primer with DNA (A)</p> Signup and view all the answers

Where are ATP molecules synthesized during respiration?

<p>Mitochondria (C)</p> Signup and view all the answers

What is the role of topoisomerase two in DNA replication?

<p>Making a double strand break and turning the DNA (A)</p> Signup and view all the answers

Which type of supercoiling occurs when a turn is removed from the DNA?

<p>Negative supercoil (B)</p> Signup and view all the answers

Which nucleotide is used to pair with cytosine (C) during DNA replication?

<p>Guanine (G) (D)</p> Signup and view all the answers

Which enzyme is responsible for proofreading and cutting out wrongly attached bases during DNA replication?

<p>DNA polymerase three (C)</p> Signup and view all the answers

Where are the triphosphates used for DNA synthesis located?

<p>Nucleus (B)</p> Signup and view all the answers

What is the function of atelomerase in stem cells and germ cells?

<p>To synthesize a long stretch of DNA (B)</p> Signup and view all the answers

What is the function of the PCNA clamp in DNA replication?

<p>To prevent the polymerase from falling off the DNA (A)</p> Signup and view all the answers

Which type of DNA is primarily passed along the maternal line?

<p>Mitochondrial DNA (D)</p> Signup and view all the answers

Is it necessary to study DNA replication in both prokaryotes and eukaryotes?

<p>Both prokaryotes and eukaryotes (D)</p> Signup and view all the answers

What is the main difference between prokaryotic and eukaryotic polymerases?

<p>Eukaryotic polymerases have different names (C)</p> Signup and view all the answers

Is the lecture sufficient for understanding DNA replication?

<p>No, extra research is required (D)</p> Signup and view all the answers

Which form of supercoiling is more common in DNA?

<p>Negative supercoiling (A)</p> Signup and view all the answers

What is the function of non-coding DNA in eukaryotes?

<p>To regulate gene expression (B)</p> Signup and view all the answers

What is the main function of the exonuclease activity of DNA polymerase?

<p>To remove RNA primers (C)</p> Signup and view all the answers

Which enzyme removes the RNA primers in prokaryotes during DNA replication?

<p>RNase H (D)</p> Signup and view all the answers

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