The Deamination Dilemma
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Questions and Answers

How does deamination occur?

  • Due to spontaneous hydrolysis (correct)
  • Due to exposure to UV radiation
  • Due to replication errors
  • Due to enzymatic activity

What is deamination?

  • The addition of a carboxyl group (COOH)
  • The loss of a carboxyl group (COOH)
  • The loss of an amino group (NH2) (correct)
  • The addition of an amino group (NH2)

What happens when a deamination occurs in methyl cytosine?

  • Guanine is created
  • Cytosine remains unchanged
  • Adenine is created
  • Thymine is created (correct)

What type of mutation is created if the repair system fails to repair the thymine created by deamination?

<p>Transition mutation (D)</p> Signup and view all the answers

What is the difference between the wild strand and the mutant strand after a deamination-induced transition mutation?

<p>Wild strand has C-G, mutant strand has T-A (D)</p> Signup and view all the answers

What is the name for a pyrimidine to pyrimidine change in a transition mutation?

<p>Transition mutation (A)</p> Signup and view all the answers

Flashcards

Deamination

The removal of an amino group (NH2) from a molecule.

Hydrolysis

A spontaneous chemical reaction where water breaks a chemical bond.

Deamination of methyl cytosine

The conversion of methyl cytosine to thymine.

Transition mutation

A type of mutation where one purine base is replaced by another purine base, or one pyrimidine base is replaced by another pyrimidine base.

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Wild strand

The original DNA sequence before any mutations.

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Mutant strand

The altered DNA sequence after a mutation.

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