Platelet Cytoskeleton Components

150-400x10^9/L

glucose

7-10 days (Rodak: 8-9 days)

<p>Thrombopoietin</p> Signup and view all the answers

<p>Mitochondrion</p> Signup and view all the answers

<p>Dense body</p> Signup and view all the answers

<p>Actin</p> Signup and view all the answers

<p>Lysosome</p> Signup and view all the answers

<p>Slows the transition from mitosis to endomitosis by preventing actin and myosin cytoskeleton and cytokinesis</p> Signup and view all the answers

<p>Indicates a hematologic disease</p> Signup and view all the answers

<p>Indention begins, abundant cytoplasm with few fine azurophilic granules, more developed demarcation system</p> Signup and view all the answers

<p>Intense indentation and lobulation, lobulated nucleus, basophilic chromatin pattern, visible and defined demarcation system, azurophilic and granular, platelet shedding, alpha and dense granules</p> Signup and view all the answers

<p>Enhances platelet interaction with its environment. Route for endocytosis and secretion of alpha granules upon activation.</p> Signup and view all the answers

<p>VWF is stored in Weibel palade bodies and serves as a substrate for platelet adhesion.</p> Signup and view all the answers

<p>Platelet and VWF is regulated by ADAMTS-13 (VWF cleaving protease).</p> Signup and view all the answers

<p>At high shear rates, platelets bind to collagen via GP VI, triggering an internal platelet activation pathway.</p> Signup and view all the answers

<p>The release of ADP and TXA2, which are potent vasoconstrictors.</p> Signup and view all the answers

<p>It causes an increase in the affinity of integrin a2B1 for collagen, platelet shape change, and activation of neighboring platelets.</p> Signup and view all the answers