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Questions and Answers
Which pathway of complement activation is triggered by binding of C1 to antibody (IgM or IgG) that has combined with antigen?
Which pathway of complement activation is triggered by binding of C1 to antibody (IgM or IgG) that has combined with antigen?
- Classical pathway (correct)
- Alternative pathway
- Lectin pathway
- None of the above
Which complement pathway is triggered by microbial surface molecules, polysaccharides, and cobra venom in the absence of antibody?
Which complement pathway is triggered by microbial surface molecules, polysaccharides, and cobra venom in the absence of antibody?
- Classical pathway
- Alternative pathway (correct)
- Lectin pathway
- None of the above
Which plasma protein binds to carbohydrates on microbes and directly activates C1 in the lectin pathway?
Which plasma protein binds to carbohydrates on microbes and directly activates C1 in the lectin pathway?
- C6
- C3
- Mannose-binding lectin (correct)
- C5
Which complement product is responsible for increased vascular permeability, chemotaxis, opsonization, and proteolysis of C3?
Which complement product is responsible for increased vascular permeability, chemotaxis, opsonization, and proteolysis of C3?
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Which component is critical in complement activation and is the most abundant component of complement products?
Which component is critical in complement activation and is the most abundant component of complement products?
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