10 Questions
Which of the following is a characteristic of the complement system?
It is required to complement the bactericidal effects of antibodies
Where are the complement proteins mainly produced?
Liver
What is the term used to describe the mode of activation of complement factors?
Complement activation cascade
What happens to complement factors when they become activated?
They are split into a small fragment (a) and a large fragment (b)
How many pathways are there for complement activation?
3
Which of the following is NOT a characteristic of the complement system?
Complement factors are heat-labile proteins
What is the term used to describe the small fragment produced when complement factors become activated?
By-product
Which pathway of complement activation is triggered by the binding of antibodies to antigens?
Classical pathway
Which complement factor is responsible for the amplification of the complement activation process?
Properdin
Which of the following is NOT a location where complement factors are normally found?
Urine
Study Notes
Complement System Characteristics
- A characteristic of the complement system is that it is a part of the immune system that helps eliminate pathogens from the body.
Complement Protein Production
- Complement proteins are mainly produced in the liver.
Complement Factor Activation
- The mode of activation of complement factors is known as a cascade reaction.
Effects of Activation
- When complement factors become activated, they are proteolytically cleaved into smaller fragments.
Complement Activation Pathways
- There are three pathways for complement activation: the classical pathway, the alternative pathway, and the lectin pathway.
Complement System Characteristics
- The complement system is NOT an adaptive immune response.
Complement Fragmentation
- The small fragment produced when complement factors become activated is called an anaphylatoxin.
Antibody-Dependent Complement Activation
- The classical pathway of complement activation is triggered by the binding of antibodies to antigens.
Complement Amplification
- Complement factor C3 is responsible for the amplification of the complement activation process.
Complement Factor Location
- Complement factors are NOT normally found in the eyes.
Test your knowledge of the complement system, a group of proteins responsible for enhancing the bactericidal effects of antibodies. Learn about the different complement factors and their functions in this informative quiz by Dr. Heba Ahmed.
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