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Questions and Answers
What is the primary function of chondrocytes in hyaline cartilage?
What is the primary function of chondrocytes in hyaline cartilage?
- To synthesize and maintain all components of the extracellular matrix (correct)
- To provide tensile strength and shape through the formation of a fibrillary meshwork
- To give cartilage its resilience and lubricating capabilities
- To secrete metalloproteinases that degrade cartilage matrix
What is the main constituent of the dry weight of cartilage matrix?
What is the main constituent of the dry weight of cartilage matrix?
- Inorganic salts
- Water
- Collagens (correct)
- Non-collagenous proteins
What is the percentage of type II collagen in hyaline cartilage?
What is the percentage of type II collagen in hyaline cartilage?
- 90%-95% (correct)
- 50%-60%
- 70%-80%
- 100%
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Study Notes
- Chondrocytes synthesize and maintain the extracellular matrix of hyaline cartilage.
- Chondrocytes can be singular or in isogenous groups, which represent recently divided cells.
- Newly divided chondrocytes produce matrix material and secrete metalloproteinases to degrade cartilage matrix.
- 60-70% of cartilage's wet weight is water and inorganic salts, providing resilience and lubrication.
- The remaining constituents are structural macromolecules: collagens, PGs, and non-collagenous proteins.
- 40-70% of cartilage's dry weight is collagen.
- Type II collagen accounts for 90-95% of the collagen in hyaline cartilage.
- Type II collagen forms a fibrillary meshwork that provides tensile strength and shape.
- Cartilage properties vary with age and location.
- Metalloproteinases allow chondrocytes to expand and reposition within isogenous groups.
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