The Autonomic Nervous System (ANS)

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Questions and Answers

Which of the following is NOT a primary function of the autonomic nervous system (ANS)?

  • Controlling conscious movement (correct)
  • Regulating heart rate
  • Maintaining body temperature
  • Managing digestion

Which division of the autonomic nervous system is most active during periods of high stress or physical activity?

  • Enteric nervous system
  • Somatic nervous system
  • Parasympathetic nervous system
  • Sympathetic nervous system (correct)

What is the primary role of the parasympathetic nervous system?

  • To promote relaxation and conserve energy (correct)
  • To mobilize energy reserves
  • To increase heart rate and blood pressure
  • To prepare the body for intense physical activity

Which neurotransmitter is primarily associated with the parasympathetic nervous system?

<p>Acetylcholine (C)</p> Signup and view all the answers

Where do the nerves of the sympathetic nervous system originate?

<p>Thoracic and lumbar regions of the spinal cord (D)</p> Signup and view all the answers

Which of the following physiological responses is NOT typically associated with sympathetic nervous system activation?

<p>Increased digestion (C)</p> Signup and view all the answers

What is the anatomical location of parasympathetic ganglia?

<p>Near or within target organs (B)</p> Signup and view all the answers

Which of the following functions is primarily controlled by the enteric nervous system?

<p>Regulation of gastrointestinal function (D)</p> Signup and view all the answers

How does the enteric nervous system communicate with the central nervous system?

<p>Via the sympathetic and parasympathetic nerves (D)</p> Signup and view all the answers

Which neurotransmitter is released by the adrenal medulla to enhance sympathetic nervous system activity?

<p>Epinephrine and norepinephrine (C)</p> Signup and view all the answers

What is the effect of sympathetic nervous system activation on blood flow?

<p>Increases blood flow to skeletal muscles. (D)</p> Signup and view all the answers

Which of the following neurotransmitters is NOT utilized by the enteric nervous system?

<p>Glutamate (D)</p> Signup and view all the answers

How do the sympathetic and parasympathetic nervous systems work together to maintain homeostasis?

<p>They often work in opposition to maintain balance (C)</p> Signup and view all the answers

Which of the following conditions is associated with disruptions in autonomic nervous system function?

<p>Postural orthostatic tachycardia syndrome (POTS) (D)</p> Signup and view all the answers

How does the location of sympathetic ganglia differ from that of parasympathetic ganglia?

<p>Sympathetic ganglia are located near the spinal cord; parasympathetic ganglia are located near or within target organs (A)</p> Signup and view all the answers

Which of the following would likely occur if the sympathetic nervous system were artificially stimulated?

<p>Increased blood glucose levels (D)</p> Signup and view all the answers

A pharmaceutical company is developing a drug to treat irritable bowel syndrome (IBS). Which of the following systems would be the MOST appropriate target for this medication?

<p>Enteric nervous system (A)</p> Signup and view all the answers

Which of the following best describes the role of the adrenal medulla in the sympathetic nervous system response?

<p>It produces hormones that prolong sympathetic effects. (A)</p> Signup and view all the answers

If a patient is experiencing excessive salivation and slowed heart rate, which branch of the autonomic nervous system is likely dominant?

<p>Parasympathetic nervous system (D)</p> Signup and view all the answers

How does the autonomic nervous system contribute to the regulation of blood pressure?

<p>By adjusting heart rate and blood vessel diameter (C)</p> Signup and view all the answers

Which component of the autonomic nervous system is responsible for the increased sweating observed during the 'fight or flight' response?

<p>Sympathetic nervous system (B)</p> Signup and view all the answers

A researcher is studying the effect of a new drug on digestion. Which branch of the autonomic nervous system would be of MOST interest?

<p>Parasympathetic nervous system and Enteric nervous system (D)</p> Signup and view all the answers

A patient has a spinal cord injury that disrupts sympathetic outflow from the thoracic and lumbar regions. Which of the following symptoms would MOST likely result from this injury?

<p>Difficulty regulating blood pressure (B)</p> Signup and view all the answers

After administering a drug, a researcher notices that a patient's pupils are constricted, their heart rate has decreased, and their digestive activity has increased. Which type of receptor was MOST likely targeted by this drug?

<p>Muscarinic cholinergic receptors (D)</p> Signup and view all the answers

A toxin selectively inhibits the release of norepinephrine. Which of the following physiological responses would be LEAST affected by this toxin?

<p>Digestion of a meal (D)</p> Signup and view all the answers

A researcher discovers a new neuron type in the enteric nervous system that releases a substance that inhibits smooth muscle contraction in the stomach. Which of the following neurotransmitters is MOST likely released by this neuron?

<p>Nitric oxide (A)</p> Signup and view all the answers

A patient presents with symptoms including chronic constipation, difficulty swallowing, and decreased gastric motility. Further testing reveals selective damage to neurons within the myenteric plexus of the enteric nervous system. Which of the following neurotransmitters would MOST likely be deficient in this patient?

<p>Vasoactive intestinal peptide (VIP) (B)</p> Signup and view all the answers

Which of the following scenarios BEST exemplifies the opposing actions of the sympathetic and parasympathetic nervous systems in maintaining cardiovascular homeostasis?

<p>In response to a sudden drop in blood pressure, the sympathetic system increases heart rate and constricts blood vessels, while the parasympathetic system simultaneously promotes vasodilation to prevent excessive blood pressure elevation. (D)</p> Signup and view all the answers

A novel drug is developed that selectively inhibits the reuptake of acetylcholine in the synapse. Which of the following effects would MOST likely be observed in a patient treated with this drug?

<p>Pupil constriction and decreased heart rate (C)</p> Signup and view all the answers

A researcher is investigating the effects of a drug that selectively blocks nicotinic receptors at the neuromuscular junction, but spares nicotinic receptors in the autonomic ganglia. Which of the following physiological responses would be MOST directly affected by this drug?

<p>Skeletal muscle contraction (D)</p> Signup and view all the answers

A genetic mutation results in a complete loss of function of beta-2 adrenergic receptors in the lungs. Which of the following physiological responses would be MOST significantly impaired in an individual with this mutation?

<p>Bronchodilation in response to sympathetic activation (A)</p> Signup and view all the answers

How are the effects of norepinephrine and epinephrine similar and different in mediating the sympathetic nervous system response?

<p>Both prepare the body for 'fight or flight'; norepinephrine is a neurotransmitter, epinephrine is a hormone (A)</p> Signup and view all the answers

Damage to the vagus nerve would MOST directly impact the function of which of the following?

<p>Parasympathetic control of the digestive system (B)</p> Signup and view all the answers

A researcher aims to develop a highly selective drug that only targets the sympathetic nervous system's effect on the heart, without affecting other sympathetic functions such as sweating or vasoconstriction. Which receptor subtype should this drug MOST selectively target?

<p>Beta-1 adrenergic receptors (C)</p> Signup and view all the answers

Damage limited to preganglionic neurons of the sympathetic nervous system would MOST directly impair the function of which of the following?

<p>Adrenal medulla (D)</p> Signup and view all the answers

Which of the following pharmacological interventions would MOST effectively and selectively inhibit the parasympathetic nervous system's influence on the sinoatrial (SA) node of the heart?

<p>Local application of atropine directly to the SA node (C)</p> Signup and view all the answers

A researcher discovers a novel neurotoxin that selectively targets and destroys intrinsic primary afferent neurons (IPANs) within the enteric nervous system. Which of the following physiological consequences would MOST likely result from exposure to this neurotoxin?

<p>Uncoordinated and ineffective intestinal motility, with impaired responses to changes in luminal stimuli (A)</p> Signup and view all the answers

Flashcards

Autonomic Nervous System (ANS)

A control system that acts largely unconsciously and regulates bodily functions.

Sympathetic Nervous System (SNS)

Prepares the body for stress; the "fight or flight" system.

Parasympathetic Nervous System (PNS)

Promotes calming of the nerves; the "rest and digest" system.

Enteric Nervous System (ENS)

Controls the gastrointestinal system; the "brain of the gut".

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SNS Effects

Increases heart rate, blood pressure, and respiration.

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SNS Origin

Thoracic and lumbar regions of the spinal cord.

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Sympathetic Ganglia

Located near the spinal cord, forming the sympathetic chain.

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Adrenal Medulla Role

Release epinephrine (adrenaline) and norepinephrine into the bloodstream to prolong sympathetic effects.

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SNS Neurotransmitters

Norepinephrine and epinephrine.

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SNS Inhibition

Inhibits non-essential functions like digestion during emergencies.

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PNS Effects

Slows heart rate, lowers blood pressure, and stimulates digestion.

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PNS Origin

Brainstem and sacral spinal cord.

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Parasympathetic Ganglia

Located near or within the target organs.

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PNS Neurotransmitter

Acetylcholine.

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PNS Enhancement

Enhances digestion, nutrient absorption, and energy storage.

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ENS Function

Regulates digestion, motility, and secretion without direct control from the brain or spinal cord.

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ENS Neurons

Sensory neurons, interneurons, and motor neurons.

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ENS Neurotransmitters

Acetylcholine, serotonin, and nitric oxide.

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Neurotransmitters

Chemical messengers that transmit signals across synapses.

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Acetylcholine Role

Primary neurotransmitter of the parasympathetic nervous system.

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Norepinephrine Role

Primary neurotransmitter of the sympathetic nervous system.

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Homeostasis

Maintenance of a stable internal environment.

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ANS in Homeostasis

Regulates key variables such as body temperature, blood pressure, and blood glucose levels.

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SNS and PNS Balance

Work in opposition to maintain balance.

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Study Notes

  • The autonomic nervous system (ANS) is a control system that acts largely unconsciously and regulates bodily functions

Divisions of the Autonomic Nervous System

  • The autonomic nervous system has three main divisions: the sympathetic nervous system, the parasympathetic nervous system and the enteric nervous system
  • The sympathetic nervous system (SNS) is often characterized as the "fight or flight" system, and prepares the body for stress
  • The parasympathetic nervous system (PNS) is often characterized as the "rest and digest" or "feed and breed" system that promotes calming of the nerves
  • The enteric nervous system (ENS) is often characterized as the "brain of the gut", and controls the gastrointestinal system

Sympathetic Nervous System

  • The sympathetic nervous system prepares the body for intense physical activity and is often referred to as the "fight or flight" response
  • When activated, the SNS increases heart rate, blood pressure, and respiration
  • The SNS also diverts blood flow away from the digestive system and towards skeletal muscles
  • Anatomically the SNS originates in the thoracic and lumbar regions of the spinal cord
  • Most sympathetic nerves originate from neurons in the lateral horn of the spinal cord
  • Sympathetic ganglia are located near the spinal cord, forming the sympathetic chain
  • The adrenal medulla are part of the sympathetic nervous system and release epinephrine (adrenaline) and norepinephrine into the bloodstream to prolong sympathetic effects
  • The neurotransmitters primarily used by the sympathetic nervous system are norepinephrine and epinephrine
  • Sympathetic activation results in increased alertness, energy availability, and muscle readiness
  • The SNS inhibits non-essential functions like digestion during emergencies

Parasympathetic Nervous System

  • The parasympathetic nervous system promotes relaxation and conserves energy and is often referred to as the "rest and digest" system
  • The PNS slows heart rate, lowers blood pressure, and stimulates digestion
  • Anatomically, the PNS originates in the brainstem and sacral spinal cord
  • Parasympathetic ganglia are located near or within the target organs
  • The neurotransmitter primarily used by the parasympathetic nervous system is acetylcholine
  • Parasympathetic activation leads to a state of calm and promotes restoration of bodily resources
  • The PNS enhances digestion, nutrient absorption, and energy storage

Enteric Nervous System

  • The enteric nervous system is an independent network of nerves within the gastrointestinal tract and is often referred to as the "brain of the gut"
  • The ENS regulates digestion, motility, and secretion without direct control from the brain or spinal cord
  • The ENS contains sensory neurons, interneurons, and motor neurons
  • It is capable of operating autonomously, using local reflexes to control gut function
  • The ENS communicates with the central nervous system (CNS) via the sympathetic and parasympathetic nerves
  • The ENS uses a variety of neurotransmitters, including acetylcholine, serotonin, and nitric oxide

Neurotransmitters of the Autonomic Nervous System

  • Neurotransmitters are chemical messengers that transmit signals across synapses
  • Acetylcholine is the primary neurotransmitter of the parasympathetic nervous system
  • It is used at preganglionic synapses in both the sympathetic and parasympathetic nervous systems
  • Norepinephrine is the primary neurotransmitter of the sympathetic nervous system
  • Epinephrine is released by the adrenal medulla and reinforces sympathetic effects
  • Different subtypes of adrenergic and cholinergic receptors mediate diverse effects in target tissues
  • The effects of a neurotransmitter depend on the type of receptor it binds to

Homeostasis and the Autonomic Nervous System

  • Homeostasis is the maintenance of a stable internal environment and is achieved through the coordinated action of the ANS and other systems
  • The autonomic nervous system regulates key variables such as body temperature, blood pressure, and blood glucose levels
  • Feedback loops involving the ANS help maintain optimal physiological conditions
  • The sympathetic and parasympathetic nervous systems often work in opposition to maintain balance
  • For example, the SNS increases heart rate, while the PNS decreases it
  • Disruptions in autonomic function can lead to various disorders, including hypertension, postural orthostatic tachycardia syndrome (POTS), and irritable bowel syndrome (IBS).

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