Podcast
Questions and Answers
Which condition is associated with the presence of four defective alleles?
Which condition is associated with the presence of four defective alleles?
- Thalassemia Type Alpha-thalassemia trait
- Hemoglobin Bart's disease (correct)
- Hemoglobin H disease
- Silent carrier Alpha thalassemia
What is a characteristic clinical feature of Beta-thalassemia major?
What is a characteristic clinical feature of Beta-thalassemia major?
- No anemia
- Low risk of hemolysis
- Prominent zygomatic bones
- Growth retardation (correct)
Which type of thalassemia can present with hepatosplenomegaly?
Which type of thalassemia can present with hepatosplenomegaly?
- Beta-thalassemia minor
- Beta-thalassemia major (correct)
- Sickle cell beta thalassemia
- Alpha-thalassemia trait
What is the characteristic of Silent carrier Alpha thalassemia?
What is the characteristic of Silent carrier Alpha thalassemia?
Which condition is a combination of one defective β-globin allele and one defective HbS allele?
Which condition is a combination of one defective β-globin allele and one defective HbS allele?
Which genetic condition is characterized by severe hepatosplenomegaly, intrauterine ascites, and hydrops fetalis, making it incompatible with life?
Which genetic condition is characterized by severe hepatosplenomegaly, intrauterine ascites, and hydrops fetalis, making it incompatible with life?
Which diagnostic finding helps differentiate between thalassemia and iron deficiency anemia?
Which diagnostic finding helps differentiate between thalassemia and iron deficiency anemia?
What finding on peripheral blood smear is characteristic of thalassemia?
What finding on peripheral blood smear is characteristic of thalassemia?
Which test is used for qualitative and quantitative analysis of hemoglobin variants?
Which test is used for qualitative and quantitative analysis of hemoglobin variants?
What is the characteristic skull x-ray finding in patients with craniofacial abnormalities due to thalassemia?
What is the characteristic skull x-ray finding in patients with craniofacial abnormalities due to thalassemia?
