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Questions and Answers
Which type of anemia do Erythrocyte indices generally indicate in Thalassemia syndromes?
What is the result of total lack of α- or β-globin production?
What is Thalassemia characterized by?
What is the inheritance pattern of Thalassemia?
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What is the result of gene deletions on Chromosome 16 in Alpha Thalassemia?
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What is the Greek word for Great Sea?
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What is the most common single gene disorder?
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What is the result of total lack of α-globin production?
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Which chromosome is affected by point mutations in Beta Thalassemia?
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What is the inheritance pattern of Thalassemia?
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Study Notes
Thalassemia Syndromes
- Erythrocyte indices generally indicate Microcytic Anemia in Thalassemia syndromes.
Characteristics of Thalassemia
- Thalassemia is characterized by reduced synthesis of globin chains of hemoglobin, leading to anemia.
Inheritance Pattern
- Thalassemia has an Autosomal Recessive inheritance pattern.
Alpha Thalassemia
- The result of total lack of α-globin production is Hydrops Fetalis, which is usually fatal.
- Gene deletions on Chromosome 16 can cause Alpha Thalassemia.
Beta Thalassemia
- The result of total lack of β-globin production is Beta Thalassemia Major, which is a severe anemia.
- Point mutations on Chromosome 11 can cause Beta Thalassemia.
Miscellaneous
- The Greek word for Great Sea is "Thalassa", which is where the name Thalassemia comes from.
- Thalassemia is the most common single gene disorder.
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Description
Test your knowledge of thalassemia with this quiz based on the hematology lecture for the 1st semester of the School of Medical Technology. Explore the characteristics and origins of thalassemia, also known as Von Jaksch Anemia or Cooley’s Anemia, and its impact on hemoglobin synthesis.
