Th2-Type Immune Responses and Chronic Inflammation Quiz
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Questions and Answers

What is the main physiological result of asthma on the airways?

  • Decreased lung function
  • Modulation of immunologic balance
  • Hyperreactivity (correct)
  • Enhancement of pro-inflammatory cytokines
  • Which of the following is NOT a common type of asthma based on the provided information?

  • Moderate persistent (correct)
  • Acute allergic
  • Seasonal
  • Occupational
  • What is regarded as one of the most common allergic diseases?

  • Bronchial asthma (BA) (correct)
  • Emphysema
  • Cystic fibrosis
  • COPD
  • What contributes to the underlying pathophysiology of asthma?

    <p>Mucous hypersecretion and bronchial hyperresponsiveness</p> Signup and view all the answers

    Which mechanism has been suggested as a possible link between obesity and the occurrence of asthma?

    <p>Enhancement of pro-inflammatory cytokines</p> Signup and view all the answers

    What stimulates the inflammatory response in asthma due to hypoxia?

    <p>Mast cells</p> Signup and view all the answers

    Which classification of asthma includes symptoms like wheeze, shortness of breath, chest tightness, and cough?

    <p>Moderate</p> Signup and view all the answers

    What is the hallmark of asthma in relation to its symptoms?

    <p>Variable</p> Signup and view all the answers

    Which antibody is associated with the allergic reaction in asthma?

    <p>IgE</p> Signup and view all the answers

    Which genetic factor has been implicated in a person's susceptibility to asthma?

    <p>Chromosome 11</p> Signup and view all the answers

    What is one of the promising sites for investigation in relation to asthma predisposition?

    <p>Chromosome 5</p> Signup and view all the answers

    Which molecules play a role in the inflammatory response seen in asthma?

    <p>Cytokines and growth factors</p> Signup and view all the answers

    What is one of the key mechanisms underlying acute asthma exacerbation?

    <p>Production of Arachidonic acid due to antigen-antibody interactions</p> Signup and view all the answers

    In asthma, what happens when an individual is sensitized and re-exposed to an allergen?

    <p>Mast cells release histamine and cytokines causing inflammation</p> Signup and view all the answers

    What role does immunoglobulin E (IgE) play in the pathophysiology of asthma?

    <p>IgE binds to mast cells, leading to the release of inflammatory mediators</p> Signup and view all the answers

    What is a characteristic feature of atopic individuals in relation to their immune system?

    <p>Elevated levels of IgE in their immune system</p> Signup and view all the answers

    What is a consequence of the binding of allergen to IgE on mast cells during an allergic reaction in asthma?

    <p>Release of inflammatory mediators like histamine</p> Signup and view all the answers

    Which process leads to airway obstruction and eventual lung damage in asthma?

    <p>Increased mucous production</p> Signup and view all the answers

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