Th2-Type Immune Responses and Chronic Inflammation Quiz

Play an AI-generated podcast conversation about this lesson

What is the main physiological result of asthma on the airways?

Decreased lung function

Modulation of immunologic balance

Hyperreactivity (correct)

Enhancement of pro-inflammatory cytokines

Which of the following is NOT a common type of asthma based on the provided information?

Moderate persistent (correct)

Acute allergic

Seasonal

Occupational

What is regarded as one of the most common allergic diseases?

Bronchial asthma (BA) (correct)

Emphysema

Cystic fibrosis

COPD

What contributes to the underlying pathophysiology of asthma?

Mucous hypersecretion and bronchial hyperresponsiveness Signup and view all the answers

Which mechanism has been suggested as a possible link between obesity and the occurrence of asthma?

Enhancement of pro-inflammatory cytokines Signup and view all the answers

What stimulates the inflammatory response in asthma due to hypoxia?

Mast cells Signup and view all the answers

Which classification of asthma includes symptoms like wheeze, shortness of breath, chest tightness, and cough?

Moderate Signup and view all the answers

What is the hallmark of asthma in relation to its symptoms?

Variable Signup and view all the answers

Which antibody is associated with the allergic reaction in asthma?

IgE Signup and view all the answers

Which genetic factor has been implicated in a person's susceptibility to asthma?

Chromosome 11 Signup and view all the answers

What is one of the promising sites for investigation in relation to asthma predisposition?

Chromosome 5 Signup and view all the answers

Which molecules play a role in the inflammatory response seen in asthma?

Cytokines and growth factors Signup and view all the answers

What is one of the key mechanisms underlying acute asthma exacerbation?

Production of Arachidonic acid due to antigen-antibody interactions Signup and view all the answers

In asthma, what happens when an individual is sensitized and re-exposed to an allergen?

Mast cells release histamine and cytokines causing inflammation Signup and view all the answers

What role does immunoglobulin E (IgE) play in the pathophysiology of asthma?

IgE binds to mast cells, leading to the release of inflammatory mediators Signup and view all the answers

What is a characteristic feature of atopic individuals in relation to their immune system?

Elevated levels of IgE in their immune system Signup and view all the answers

What is a consequence of the binding of allergen to IgE on mast cells during an allergic reaction in asthma?

Release of inflammatory mediators like histamine Signup and view all the answers

Which process leads to airway obstruction and eventual lung damage in asthma?

Increased mucous production Signup and view all the answers