Test Your Genetics Knowledge
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Questions and Answers

Which gene locus is NOT associated with the formation of Axenfeld Rieger Syndrome (ARS)?

  • PITX2 on ch 4q25
  • FOXO1A on 13q14 (correct)
  • FOXC1 on 6p25
  • PAX6 on 11p13

    • What is the clinical manifestation of ARS in the anterior chamber of the eye?

  • Abnormal development of the optic nerve
  • Abnormal development of the retina
  • Abnormal development of the cornea, lens, pupil, and limbus (correct)
  • Abnormal development of the iris and trabecular meshwork

    • What is gene therapy and its current status for the treatment of genetic defects related to ARS?

  • A technique of using radiation to destroy mutated genes
  • A type of surgery that corrects genetic defects in the eye
  • A type of medication that targets mutated genes
  • A method of inserting healthy genes into cells to replace or repair damaged genes (correct)

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