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Lecture 19

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20 Questions

What is the term used to describe the study of birth defects?

Teratology

What is a teratogen?

A substance that induces or amplifies abnormal embryonic or fetal development

Which of the following is an example of an infectious agent that can cause birth defects?

Cytomegalovirus

What is the effect of ionizing radiation on the conceptus?

It can produce any type of birth defect

What is an example of a maternal condition that can cause birth defects?

Hormonal imbalance

What is an example of a numerical chromosomal abnormality?

Trisomy 21

What is a result of a mutation?

A change in the function of a gene

What is an example of a genetic cause of birth defects?

Trisomy 21

What is the term used to describe the study of the causes of birth defects?

Teratology

What is an example of a physical teratogen?

Ionizing radiation

What is the primary cause of malformations?

Environmental and genetic factors

What is the typical time period during which most malformations occur?

During the 3rd/8th weeks of gestation

What is the result of an intrinsically abnormal developmental process?

Malformation

What is the term for a morphologic defect that results from exposure to teratogens?

Disruption

What is the cause of clubfeet (equinovarus)?

Compression in the amniotic cavity

What is the term for an abnormal form, shape, or position of a part of the body?

Deformation

What is the result of mechanical forces on the body?

Deformation

What is the term for a partial disruption of the abdominal wall in the area supplied by the right omphalo-mesenteric artery?

Gastroschisis

What is the result of fetal constraint associated with oligohydramnios?

Deformation

What is the term for the abnormal development of an organ or part of an organ?

Malformation

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