TDEE, RMR and Caloric Intake
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An individual with a desk job who engages in light exercise twice a week wants to estimate their Total Daily Energy Expenditure (TDEE). Which activity factor (AF) from the provided chart should they use to multiply their Resting Metabolic Rate (RMR)?

  • 1.2
  • 1.725
  • 1.375 (correct)
  • 1.55

A construction worker engages in hard daily exercise and sports. Which activity factor should they use to estimate their TDEE?

  • 1.9 (correct)
  • 1.725
  • It depends on their RMR
  • 1.55

A 30-year-old male, weighing 75 kg and standing 180 cm tall, leads a sedentary lifestyle. Using the Harris-Benedict equation for males, what is his estimated Resting Metabolic Rate (RMR)?

  • Approximately 1750 kcals
  • Approximately 1650 kcals
  • Approximately 1800 kcals (correct)
  • Approximately 1900 kcals

How would an individual adjust their caloric intake based on their TDEE if their goal was weight loss?

<p>Consume slightly below their TDEE. (B)</p> Signup and view all the answers

A moderately active female wants to gain weight. After calculating her TDEE using RMR and an appropriate activity factor, what adjustment should she make to her daily caloric intake?

<p>Consume calories slightly above her calculated TDEE. (C)</p> Signup and view all the answers

Which component contributes the most to an individual's Total Daily Energy Expenditure (TDEE)?

<p>Basal Metabolic Rate (BMR) (B)</p> Signup and view all the answers

Why is Resting Metabolic Rate (RMR) more commonly measured than Basal Metabolic Rate (BMR) in research settings?

<p>RMR assessment doesn't require overnight stay in a lab, making it more practical. (A)</p> Signup and view all the answers

Metabolic carts directly measure which of the following components to assess metabolic rate?

<p>Percentages of oxygen and carbon dioxide in expired breath, and the volume of that breath. (D)</p> Signup and view all the answers

A researcher wants to measure a subject's RMR accurately. Which of the following conditions is NOT required?

<p>Abstaining from any exercise for at least 12 hours (C)</p> Signup and view all the answers

Why is it important to account for local barometric pressure and ambient temperature when using a metabolic cart?

<p>They affect the volume of expired gas, which is a critical component of measurement. (A)</p> Signup and view all the answers

According to the Weir equation, how does the measurement of VO2 and VCO2 contribute to the calculation of RMR?

<p>VO<del>2</del> and VCO<del>2</del> are directly proportional to RMR; higher VO<del>2</del> and VCO<del>2</del> indicate higher RMR. (B)</p> Signup and view all the answers

For best results, how often should data be averaged when using a metabolic cart?

<p>Using one-minute averages to balance accuracy and practicality. (A)</p> Signup and view all the answers

In indirect calorimetry, what happens to the concentration of gases in expired breath compared to the atmospheric concentration?

<p>Oxygen decreases, carbon dioxide increases, and nitrogen remains unchanged. (C)</p> Signup and view all the answers

Why are prediction equations commonly used to estimate RMR in field settings?

<p>Direct assessment is cumbersome, costly, and requires trained technicians. (A)</p> Signup and view all the answers

According to the information provided, what is the number one determining factor for the validity of a selected RMR prediction equation?

<p>The population in which the equation was developed. (C)</p> Signup and view all the answers

A subject's VO2 is measured at 0.25 L/min and VCO2 is 0.2 L/min. Using the Weir equation, calculate their RMR.

<p>1.44 [(0.25 3.9) + (0.2 1.1)] (A)</p> Signup and view all the answers

If a metabolic cart measures a subject's expired breath and finds that the carbon dioxide concentration has not increased relative to atmospheric levels, what might this indicate?

<p>There may be an error in the metabolic cart's measurement. (C)</p> Signup and view all the answers

Which of the following statements is true regarding the accuracy of RMR prediction equations?

<p>A body weight-based equation utilized in the right population will outperform a body composition-based equation in the wrong population. (B)</p> Signup and view all the answers

Why is it recommended to conduct RMR assessments in the morning?

<p>To aid in participant comfort, as the majority of fasting hours will occur overnight while sleeping. (D)</p> Signup and view all the answers

What is the purpose of an activity factor (AF) when estimating TDEE?

<p>To adjust RMR based on how active a person is on average within their daily life. (A)</p> Signup and view all the answers

Which of the equations is the most accurate at predicting RMR?

<p>There is no equation in existance like that. (A)</p> Signup and view all the answers

Why is it necessary to know both the Respiratory Exchange Ratio (RER) and the amount of oxygen consumed to accurately estimate the body's energy expenditure?

<p>Because the caloric equivalent for oxygen varies depending on the nutrient being oxidized. (C)</p> Signup and view all the answers

In the context of energy production, what is the primary reason protein contribution is often disregarded when calculating RER?

<p>Protein's contribution is very small, and measuring it requires inconvenient urine collection. (B)</p> Signup and view all the answers

An individual with a Respiratory Exchange Ratio (RER) of 0.85 at rest is primarily utilizing what mixture of substrates for energy?

<p>A mix of carbohydrate and fat, with a higher proportion of fat. (C)</p> Signup and view all the answers

If a person consumes 1 liter of oxygen and has an RER of 1.0, and then later consumes another liter of oxygen and has an RER of 0.7, what can be said about the comparison of energy production between these two scenarios?

<p>The energy produced would be greater at an RER of 1.0 due to more kilocalories produced per liter of oxygen. (C)</p> Signup and view all the answers

During Resting Metabolic Rate (RMR) measurement, why is it important to measure both oxygen consumption and RER each minute?

<p>To precisely determine the caloric expenditure each minute based on the changing substrate utilization. (D)</p> Signup and view all the answers

Which equation is most appropriate for estimating the resting metabolic rate of a generally active individual?

<p><code>0.239 * [(49.94 × BM (kg)) + (2459.053 × H (meters)) - (34.014 × age) + (799.257 × sex) + 122.502]</code> (A)</p> Signup and view all the answers

An athlete engages in high-intensity training for 3 hours daily. Which equation best estimates their resting metabolic rate?

<p><code>9 * BM (kg) + 11.7 * Height (cm) - 857</code> (A)</p> Signup and view all the answers

If you are calculating resting metabolic rate using the Mifflin-St Jeor equation, what is the meaning of the 'sex' variable?

<p>A categorical variable where males = 1 and females = 0. (B)</p> Signup and view all the answers

What key variables are required by the Cunningham equation to estimate resting metabolic rate?

<p>Fat-free mass only. (D)</p> Signup and view all the answers

In respiratory physiology, what information do the Respiratory Quotient (RQ) and Respiratory Exchange Ratio (RER) provide?

<p>The primary macronutrient being oxidized for fuel. (C)</p> Signup and view all the answers

Using the RER equation, if a person produces 2.0 L/min of $VCO_2$ and consumes 2.0 L/min of $VO_2$, what is their RER value and what does it suggest?

<p>1.0, indicating a mix of carbohydrate and fat metabolism. (A)</p> Signup and view all the answers

How are the Respiratory Quotient (RQ) and Respiratory Exchange Ratio (RER) similar?

<p>They are measured at different locations but calculated using the same equation. (B)</p> Signup and view all the answers

A respiratory exchange ratio (RER) of 0.7 indicates:

<p>The subject is primarily burning fat. (D)</p> Signup and view all the answers

Flashcards

Basal Metabolic Rate (BMR)

Minimum energy to sustain vital functions while awake, measured in kcal/day.

Total Daily Energy Expenditure (TDEE)

Total kcals burned in a day; includes BMR, TEF, and Activity Thermogenesis.

Thermic Effect of Feeding (TEF)

Energy used for digestion, absorption, and metabolism of food.

Activity Thermogenesis (AT)

Energy expended through physical activity.

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Exercise Activity Thermogenesis (EAT)

Energy expended during structured exercise.

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Nonexercise Activity Thermogenesis (NEAT)

Energy expended during all activities that are not structured exercise.

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Indirect Calorimetry

Measures gas exchange (O2 consumption, CO2 production) to estimate energy expenditure.

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Weir Equation

RMR = 1.44 × [(VO2 ×3.9) + (VCO2 ×1.1)]

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Metabolic Cart Measurement

Measures oxygen and carbon dioxide percentages in breath, and breath volume.

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Environmental Factors in Metabolic Testing

Local barometric pressure and ambient temperature affect gas volume measurements.

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Optimal Data Collection for RMR

Averaging data over one-minute intervals for precision.

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RMR Prediction Equations

Estimating Resting Metabolic Rate using mathematical formulas.

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Metrics Used in RMR Equations

Height, weight, body composition, age, and sex.

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Key Factor for Prediction Equation Validity

The population it was developed in.

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Activity Factor (AF)

Converting RMR to TDEE.

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Purpose of Activity Factor

Estimating average daily activity level.

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Respiratory Exchange Ratio (RER)

Ratio of CO2 produced to O2 consumed; indicates substrate utilization.

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Energy Expenditure

The energy expenditure in kcal/min, estimated using RER and oxygen consumption.

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TDEE

Total Daily Energy Expenditure; the estimated number of calories a person needs to maintain their weight.

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Caloric Equivalent for Oxygen

Kilocalories produced for each liter of oxygen consumed (kcal/L), varies based on RER.

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RER for Carbohydrate

RER value when only carbohydrates are being utilized as a fuel source.

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RER for Fat

RER value when only fats are being utilized as a fuel source.

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Sedentary Activity Factor

Desk job with little to no exercise (multiply by 1.2).

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Extremely Active Factor

Hard daily exercise/sports and physical job or training (multiply by 1.9).

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TDEE Calculation Equation

TDEE = RMR × AF

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Mifflin-St. Jeor Equation

Estimates resting metabolic rate based on body mass, height, age, and sex; commonly used for inactive individuals.

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Cunningham Equation

Estimates resting metabolic rate using fat-free mass (FFM) plus a constant.

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DeLorenzo Equation for Athletes

Specific equations exist to calculate resting metabolic rate for athletes with high activity levels over 3 hours/day, using their body mass and height.

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Ten Haaf and Weijs Equations

Equations for RMR adjusted for generally active individuals, factoring in body mass, height, age and sex.

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Respiratory Quotient (RQ)

Ratio of carbon dioxide produced to oxygen consumed at the cellular level.

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VCO2 / VO2

The formula used to calculate both RQ and RER.

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RQ/RER Significance

Indicates the type of macronutrient being oxidized during steady state.

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Study Notes

  • The minimum energy to sustain vital bodily functions while awake is the basal metabolic rate (BMR).
  • BMR is usually expressed in kcal/day.
  • BMR makes up the majority of a person's total daily energy expenditure (TDEE).
  • TDEE consists of BMR (60-75%), the thermic effect of feeding (TEF, 10%), and activity thermogenesis (AT, 15-30%).
  • Activity thermogenesis includes exercise activity thermogenesis (EAT) and nonexercise activity thermogenesis (NEAT).
  • True BMR is hard to measure because it requires at least 8 hours of sleep and 12 hours of fasting, usually overnight in a lab.
  • As a result, researchers typically measure RMR.
  • RMR requires resting and fasting, but not an overnight stay in the lab.
  • Accepted guidelines for RMR assessment:
    • Fast for at least 8 hours from all calorie-containing foods and drinks
    • Rest in a dark, quiet room for 30 minutes before the test
    • No exercise for at least 24 hours
    • No caffeine or stimulants for at least 12 hours before the test
  • RMR can be assessed at any time if conditions are met, but morning is best.

Indirect Calorimetry

  • RMR is usually assessed through indirect calorimetry.
  • Indirect calorimetry uses metabolic carts to measure carbon dioxide (VCO2) production and oxygen (VO2) consumption with each breath.
  • Atmospheric composition: 20.93% oxygen, 0.03% carbon dioxide, and 79.04% nitrogen.
  • Oxygen decreases and carbon dioxide increases in expired breath.
  • Nitrogen remains unchanged.
  • Metabolic carts estimate RMR using the Weir equation: RMR = 1.44 × [(VO2 × 3.9) + (VCO2 × 1.1)]
  • Metabolic carts measure oxygen and carbon dioxide percentages in expired breath and breath volume.
  • Gas volume is affected by temperature and pressure.
  • Metabolic carts may measure expired gases, ventilation, and temperature and pressure for each breath.

Estimating Resting Metabolic Rate

  • Prediction equations estimate RMR using metrics like height, weight, body composition, age, and sex.
  • These equations have become more common due to the challenges of directly assessing RMR.
  • The key factor for a prediction equation's validity is the population it was developed in.
  • Body weight-based equations can outperform body composition-based equations if utilized in the right population.
  • RMR is converted to TDEE using an activity factor (AF) to estimate a person's average daily activity.
    • Sedentary: desk job, little to no exercise (multiply by 1.2)
    • Lightly Active: light exercise/sports 1–3 days/week (multiply by 1.375)
    • Moderately Active: moderate exercise/sports 3–5 days/week (multiply by 1.55)
    • Very Active: hard exercise/sports 6–7 days/week (multiply by 1.725)
    • Extremely Active: hard daily exercise/sports, physical job or training (multiply by 1.9)
  • TDEE is estimated using the equation: TDEE = RMR × AF.
  • This estimates the kilocalories needed to maintain weight.

Respiratory Exchange Ratio and Respiratory Quotient

  • Respiratory quotient (RQ) or respiratory exchange ratio (RER) indicates the fuel being used.
  • RER provides information on the macronutrient being oxidized during steady state.
  • RQ and RER differ based on cellular level (RQ) or expired gases (RER) measurements.
  • Both metrics are calculated using the equation: VCO2 / VO2
  • Ratios measure CO2 quantity produced relative to O2 consumed.
  • Carbohydrate, fat, and protein require different oxygen amounts for complete oxidation.
  • Caloric equivalent for oxygen varies; RER and oxygen consumption are needed to estimate energy expenditure (kcal/min).
  • Kilocalories per liter of oxygen depend on the substrate used or RER.
  • RER for carbohydrate is 1.0, for fat is 0.70, and for protein is 0.82.
  • Protein contribution to energy production is low (less than 5%).
  • Generally, a carbohydrate and fat mixture is oxidized by mitochondria, and kilocalories per liter of oxygen vary.
  • People with mixed diets have an RER of about 0.85 at rest, meaning about 4.86 kcal are produced per liter of oxygen.
  • RMR measurement requires oxygen consumption and RER value for each minute to determine kilocalories produced per minute.
  • Carbohydrate has an RER of 1.0, and fat has an RER of 0.7.

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Explore Total Daily Energy Expenditure (TDEE), Resting Metabolic Rate (RMR), and the factors influencing caloric intake. Learn how to calculate RMR using the Harris-Benedict equation and adjust caloric intake for weight management goals.

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