7 Questions
Which region of the TCR chain is the most variable among different TCRs?
CDR3 region
What is the composition of the TCR?
One α chain and one β chain
Which proteins are crucial for the initiation of signaling when the TCR recognizes antigen?
CD3 and ζ proteins
Which molecules recognize nonpolymorphic portions of MHC molecules and are required for T cell activation?
CD4 and CD8
Which type of receptor can bind many different types of chemical structures with high affinities?
Antibodies
Which type of T cells express receptors composed of gamma (γ) and delta (δ) chains and have different specificities than αβ TCRs?
NK-T cells
Which subset of T cells express αβ TCRs with limited diversity and recognize lipid antigens displayed by nonpolymorphic class I MHC–like molecules called CD1?
NK-T cells
Test your knowledge about TCR structure and function with this quiz! Learn about the composition of TCR, its role in recognizing peptide antigens, and the homology between TCR and immunoglobulins. Challenge yourself with questions about hypervariable regions and complementarity-determining regions.
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