TCR Structure and Function Quiz

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Questions and Answers

Which region of the TCR chain is the most variable among different TCRs?

  • V region
  • β chain
  • CDR3 region (correct)
  • C region

What is the composition of the TCR?

  • One α chain and two β chains
  • Two β chains
  • Two α chains
  • One α chain and one β chain (correct)

Which proteins are crucial for the initiation of signaling when the TCR recognizes antigen?

  • MHC molecules and bound peptides
  • CDR3 and ζ proteins
  • V and C regions
  • CD3 and ζ proteins (correct)

Which molecules recognize nonpolymorphic portions of MHC molecules and are required for T cell activation?

<p>CD4 and CD8 (A)</p> Signup and view all the answers

Which type of receptor can bind many different types of chemical structures with high affinities?

<p>Antibodies (C)</p> Signup and view all the answers

Which type of T cells express receptors composed of gamma (γ) and delta (δ) chains and have different specificities than αβ TCRs?

<p>NK-T cells (C)</p> Signup and view all the answers

Which subset of T cells express αβ TCRs with limited diversity and recognize lipid antigens displayed by nonpolymorphic class I MHC–like molecules called CD1?

<p>NK-T cells (B)</p> Signup and view all the answers

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