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TCA Cycle Regulation Quiz

Created by

@UnrestrictedSard9448

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Questions and Answers

What determines the activities of the dehydrogenases of the TCA cycle?

Regulation by citrate synthase

Continuous supply of NAD and FAD (correct)

Availability of oxygen

Presence of ATP

What is crucial in determining the rate of the TCA cycle?

Regulation of citrate synthase activity

Supply of acetyl units from pyruvate or fatty acids (correct)

Transport of NAD and FAD into mitochondria

Inhibition of the respiratory chain

What is the regulatory process called that couples the activity of the respiratory chain to the generation of ATP?

Respiratory control (correct)

Pyruvate dehydrogenase regulation

Citrate synthase coupling

Glycolytic regulation

What is strongly dependent on the rate of ATP synthesis?

Activity of the TCA cycle Signup and view all the answers

What is an effective determinant of the TCA cycle activity?

Regulation of the pyruvate dehydrogenase complex Signup and view all the answers

What is the crucial factor in determining the rate of the TCA cycle?

Supply of acetyl units Signup and view all the answers

What is an effective determinant of TCA cycle activity?

Regulation of pyruvate dehydrogenase complex Signup and view all the answers

What determines the activities of the dehydrogenases of the TCA cycle?

Continuous supply of NAD and FAD Signup and view all the answers

What is the regulatory process called that couples the activity of the respiratory chain to the generation of ATP?

Respiratory control Signup and view all the answers

What is the TCA cycle activity very dependent on?

Rate of ATP synthesis Signup and view all the answers

Study Notes

Regulation of TCA Cycle

The activities of the dehydrogenases of the TCA cycle are determined by the NAD+/NADH and FAD/FADH2 ratios.
The rate of the TCA cycle is crucially determined by the availability of NAD+ and CoA-SH.
The regulatory process that couples the activity of the respiratory chain to the generation of ATP is called respiratory control.
The rate of ATP synthesis is strongly dependent on the proton gradient across the inner mitochondrial membrane.
The availability of NAD+ and CoA-SH is an effective determinant of the TCA cycle activity.
The crucial factor in determining the rate of the TCA cycle is the availability of NAD+ and CoA-SH.
The TCA cycle activity is very dependent on the ATP/ADP ratio, which affects the activity of isocitrate dehydrogenase and alpha-ketoglutarate dehydrogenase.

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Description

Test your knowledge of the regulation of the Tricarboxylic Acid (TCA) cycle with this quiz. Explore the factors that control the supply of acetyl units and the regulation of key enzymes involved in the cycle.