TBI Advanced Testing: Beyond 3T MRI with DWI + DTI Protocol
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Questions and Answers

These are essential elements to consider during the initial TBI assessment, EXCEPT:

  • Severity of TBI
  • Time of first medical evaluation
  • Sign Up Date (correct)
  • Type of event (MVA, fall, assault or other external head trauma)
  • As part of the standard TBI testing, Non-contrast Brain Computed Tomography (CT) can provide evidence of skull fractures or brain hemorrhages.

    True

    Diffusion Tensor Imaging (DTI) 3D Tractography is considered part of the advanced MRI testing for TBI.

    True

    During Magnetic Resonance Spectroscopy (MRs) these are the common metabolites measured, EXCEPT:

    <p>Alanine (Ala)</p> Signup and view all the answers

    Arterial Spin Labeling MRI (ASL) is an invasive perfusion sequence that measures cerebral blood flow.

    <p>False</p> Signup and view all the answers

    Name the two varieties of Functional MRI (fMRI):

    <p>Resting State and Tasked-Based</p> Signup and view all the answers

    Functional magnetic resonance imaging (fMRI) BOLD imaging sequences are related to which of the following?

    <p>Blood oxygen level-dependent</p> Signup and view all the answers

    These biomarkers have been studied to be show in serum levels after TBI:

    <p>A and B are correct</p> Signup and view all the answers

    Understanding advanced neuroimaging testing for TBI is important because:

    <p>All are correct</p> Signup and view all the answers

    TBI diagnostic testing can be classified accordingly:

    <p>B and C are correct</p> Signup and view all the answers

    Study Notes

    Initial TBI Assessment

    • Essential elements for initial traumatic brain injury assessment include various imaging techniques to detect structural damage.
    • Non-contrast Brain Computed Tomography (CT) effectively identifies skull fractures and brain hemorrhages.
    • Advanced MRI testing for TBI includes Diffusion Tensor Imaging (DTI) 3D Tractography, which assesses white matter integrity.

    Magnetic Resonance Spectroscopy (MRS)

    • Common metabolites measured during MRS include N-acetylaspartate (NAA), choline, and creatine.
    • Specific metabolites or markers not typically measured by MRS need to be identified in the context of TBI assessments.

    Arterial Spin Labeling (ASL)

    • Arterial Spin Labeling MRI (ASL) is a non-invasive technique that quantitatively measures cerebral blood flow, contrary to being labeled invasive.

    Functional MRI (fMRI)

    • Two varieties of functional MRI techniques are: Blood Oxygen Level Dependent (BOLD) imaging and perfusion-based imaging.
    • BOLD imaging sequences assess the hemodynamic response related to neural activity, providing insights into brain function during cognitive tasks.

    Biomarkers After TBI

    • Several biomarkers have been researched for their presence in serum after TBI, indicating cellular response and injury severity.
    • Understanding these biomarkers aids in developing diagnostic and prognostic tools for clinical application.

    Importance of Advanced Neuroimaging

    • Advanced neuroimaging testing is crucial for accurate TBI diagnosis and management, enabling tailored treatment strategies.
    • Neuroimaging results assist in understanding the extent of injury, planning rehabilitation, and predicting patient outcomes.

    TBI Diagnostic Testing Classification

    • TBI diagnostic testing can be categorized based on the techniques used, including structural imaging (CT, MRI) and functional imaging (fMRI, ASL).

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