C12- Taste

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Questions and Answers

Taste sensory cells transmit information via synapses to sensory fibers within the taste bud.

True (A)

The primary gustative cortex is responsible for interpreting the quantity of food rather than the quality.

False (B)

Bitter is the least reactive taste receptor as age increases.

False (B)

The VPM of thalamus plays a role in connecting taste information to cortical areas responsible for taste perception.

<p>True (A)</p> Signup and view all the answers

Chewing food has no effect on the perception of its taste before and after the process.

<p>False (B)</p> Signup and view all the answers

Sour taste corresponds to the presence of glucose.

<p>False (B)</p> Signup and view all the answers

Taste receptor cells are primarily responsible for converting chemical stimuli into electrical signals.

<p>True (A)</p> Signup and view all the answers

Calcium concentration is decreased during taste cell depolarization.

<p>False (B)</p> Signup and view all the answers

An imbalance of sodium ions poses a higher risk than an imbalance of potassium ions.

<p>False (B)</p> Signup and view all the answers

Umami taste is linked to the presence of hydrogen ions.

<p>False (B)</p> Signup and view all the answers

Taste is considered a special sensory organ for the skeletal system.

<p>False (B)</p> Signup and view all the answers

Sweet taste receptors utilize a G protein-coupled mechanism to transduce taste information.

<p>True (A)</p> Signup and view all the answers

Taste receptor cells can respond to multiple substances simultaneously.

<p>True (A)</p> Signup and view all the answers

The osmotic equilibrium is primarily governed by sodium ions alone.

<p>False (B)</p> Signup and view all the answers

Taste buds are exclusively located in the tongue and do not exist in the pharynx.

<p>False (B)</p> Signup and view all the answers

Circumvallate papillae contain the highest concentration of taste buds among the three types of papillae.

<p>True (A)</p> Signup and view all the answers

Fungiform papillae are predominantly found in the posterior part of the tongue.

<p>False (B)</p> Signup and view all the answers

Taste buds regenerate every 10-15 days through the differentiation of supporting cells.

<p>False (B)</p> Signup and view all the answers

Chemoceptors in taste buds respond to an infinite variety of different substrates.

<p>False (B)</p> Signup and view all the answers

The apical portion of taste buds is responsible for the contact with the oral cavity fluids.

<p>True (A)</p> Signup and view all the answers

Foliate papillae contain no taste buds in their structure.

<p>False (B)</p> Signup and view all the answers

The 'Across neuron' hypothesis suggests that each receptor responds exclusively to a single type of taste.

<p>False (B)</p> Signup and view all the answers

Cell 1 in the experiment solely responds to sodium chloride.

<p>False (B)</p> Signup and view all the answers

The principles of the 'Labelled line' theory are based on the overall computation of brain analysis rather than individual taste receptors.

<p>False (B)</p> Signup and view all the answers

Chorda tympani fibers exhibit different response profiles to taste stimuli based on their sensitivity to temperature and taste profiles.

<p>True (A)</p> Signup and view all the answers

In the 'Labelled line' theory, a single gustatory neuron can represent multiple sensory attributes at once.

<p>False (B)</p> Signup and view all the answers

The activation of Axon 3 primarily leads to the detection of sour taste.

<p>False (B)</p> Signup and view all the answers

The threshold for activation differs among the fibers based on the type of substrate they are sensitive to.

<p>True (A)</p> Signup and view all the answers

Fibers classified as sodium chloride-best can also be sensitive to bitterness according to the experimental findings.

<p>True (A)</p> Signup and view all the answers

The 'Across neuron' hypothesis emphasizes the individual properties of each receptor rather than the combined analysis of group responses.

<p>False (B)</p> Signup and view all the answers

The discharge of chorda tympani fibers decreases significantly with increased sensitivity to salty stimuli.

<p>False (B)</p> Signup and view all the answers

Salivation in response to food can occur just from looking at it.

<p>True (A)</p> Signup and view all the answers

The T1R2 and T1R3 genes are responsible for encoding sweet receptors in humans.

<p>True (A)</p> Signup and view all the answers

Bitter taste receptors are less sensitive than sweet taste receptors.

<p>False (B)</p> Signup and view all the answers

Umami taste is primarily associated with the presence of citric acid.

<p>False (B)</p> Signup and view all the answers

Different areas of the tongue exclusively detect certain tastes, such as sweet at the tip and bitter at the back.

<p>False (B)</p> Signup and view all the answers

Chemosensory transduction begins in the basal domain of taste cells.

<p>False (B)</p> Signup and view all the answers

The transduction mechanism for taste includes both G-protein mediated activation and direct occlusion of K+ channels.

<p>True (A)</p> Signup and view all the answers

The neurotransmitter serotonin is released in the taste transduction process.

<p>True (A)</p> Signup and view all the answers

Sweetness is predominantly detected through a G-protein-independent signaling pathway.

<p>False (B)</p> Signup and view all the answers

Taste buds can only respond to the five basic taste categories: salty, sour, sweet, bitter, and umami.

<p>False (B)</p> Signup and view all the answers

Flashcards

Taste buds

Small sensory organs found in the tongue, pharynx, epiglottis, and upper esophagus, responsible for detecting taste.

Papillae

Clusters of taste buds on the tongue, categorized by their shape and location.

Fungiform Papillae

Mushroom-shaped papillae found mainly on the anterior 2/3 of the tongue.

Circumvallate Papillae

Large, round papillae surrounded by grooves, located on the posterior 1/3 of the tongue.

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Foliate Papillae

Two parallel ridges on the posterolateral tongue containing many taste buds.

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Taste Cells

Sensory cells in taste buds that respond to chemical stimuli.

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Taste Substrates

Chemical compounds that stimulate taste receptors.

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Salty Taste

The taste of sodium in food. There is a conscious experience to the content of sodium in food.

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Sour Taste

The taste of hydrogen in food. Sour is the taste of acidity.

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Sweet Taste

The taste of glucose in food.

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Umami

The taste of glutamate in food.

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Bitter Taste

The taste of various molecules or compounds that are not easily categorized.

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Salt Taste Receptor Cells

Taste cells specialized for the detection of salt.

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Sour Taste Receptor Cells

Taste cells specialized for the detection of sourness.

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Sweet Taste Receptor Cells

Taste cells specialized for the detection of glucose, trigger a signal cascade through G-Protein coupled receptors.

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Umami Taste Receptor Cells

Taste cells specialized for the detection of glutamate.

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Defensive salivation

A reflex that occurs when you taste something too acidic, involving secretion of saliva with bicarbonate ions to neutralize the acid.

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Umami taste

The taste of glutamate, activating both ionotropic and metabotropic receptors.

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Taste transduction

The process by which taste cells convert chemical signals from food into electrical signals that are transmitted to the brain.

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Serotonin in taste

A neurotransmitter released by taste cells, playing a key role in taste signal transduction.

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Taste cell domains

Apical and basal domains are important structures in taste cells, reflecting their epithelial character.

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Taste regions

The belief that different regions of the tongue specialize in detecting specific tastes.

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Taste sensitivity

Every area of your tongue can detect all five tastes, but different regions have varying sensitivity.

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Tastant

A molecule that binds to a receptor and initiates a signal transduction pathway.

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Flavor perception as a mosaic

The brain processes taste information based on the pattern of activity from different taste receptors, integrating the overall signal to create a flavor perception.

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Polymodal taste receptors

Different taste receptors respond to specific molecules, but can be sensitive to multiple substrates. The brain interprets the complex signals from these receptors to form the actual taste experience.

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Taste signal pathway

Central nervous system processing of taste information starts in the solitary tract within the medulla, then relays to the thalamus, and finally reaches the gustatory cortex for conscious perception.

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Hierarchical taste processing

The primary gustatory cortex analyzes the quality of taste information, while the secondary gustatory cortex adjusts for the volume or amount of food consumed.

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Taste synergies

Synergies in taste perception occur when the presence of one taste influences the perception of another, either enhancing or reducing its intensity.

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Labelled Line Theory

A theory of taste perception suggesting that each taste receptor is dedicated to a specific taste, leading to separate pathways in the brain for different tastes.

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Across Neuron Hypothesis

A theory of taste perception suggesting that the pattern of activity across all taste receptors is used to code for taste. It argues that the brain interprets the overall pattern of activity, not just the activation of a single receptor.

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Receptor Tuning

The ability of a receptor to respond to different taste stimuli, but with varying degrees of sensitivity. Some stimuli may trigger a strong response, while others may only elicit a weak or no response.

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Threshold

The minimum amount of a taste stimulus needed to trigger a response in a specific taste receptor.

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Response Profile

The response intensity of a taste receptor to a specific stimulus. Higher intensity indicates a stronger activation.

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Brain Computation

The process of analyzing the pattern of activity across multiple taste receptors to determine the perceived taste.

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Tuning Curves

The different ways in which taste receptors respond to various stimuli, including taste molecules and temperature.

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Taste Center

The part of the brain that receives taste information from the tongue and processes it into a perceived taste.

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Taste Alchemy

The combination of different taste receptors and their responses that contribute to the overall taste perception.

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Gustatory Pathway

The neural pathway that transmits taste information from the tongue to the brain.

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Study Notes

Taste Bud Anatomy and Function

  • Taste buds, sensory organs containing receptors, are located on the tongue, pharynx, epiglottis, and upper esophagus.
  • They cluster in papillae, specific structures on the tongue's surface.
  • Each taste bud consists of basal cells, taste cells (receptors), and supporting cells. Taste pores allow taste cells to interact with food substances in the mouth.
  • Different papillae types include fungiform (25%), circumvallate (50%), and foliate (25%), each with distinct shapes and distributions across the tongue.
  • Fungiform papillae are concentrated at the tongue tip, circumvallate papillae are located at the back, and foliate papillae are in the posterior lateral tongue areas.
  • Despite shape variations, all papillae contain taste buds.
  • Chemical stimuli initially interact with receptors on fungiform papillae, followed by foliate and then circumvallate papillae.

Taste Bud Structure and Function

  • Taste buds have an onion-like shape, with the apical portion exposed to the oral cavity fluid.
  • Taste cells are second-order receptors which do not produce action potentials; instead, they release neurotransmitters that activate afferent nerve fibers.
  • Supporting cells secrete substances within the taste bud.
  • Basal cells are a reservoir and can differentiate into new taste cells for continuous regeneration approximately every 10-15 days.

Types of Taste Stimuli

  • Taste receptors are chemoreceptors reacting to specific classes of molecules; not an infinite variety of stimuli.
  • These trigger specific taste sensations categorized as: sour, salty, sweet, bitter, and umami.
  • Sour: related to hydrogen ion concentration (pH).
  • Salty: sodium ions sensed.
  • Sweet: glucose and other molecules.
  • Bitter: diverse compounds like acids, salts, alkaloids.
  • Umami: due to glutamate interaction.

Mechanisms of Taste Transduction

  • Taste cells transduce chemical stimuli into electrical signals.
  • This action is based on a ligand to receptor binding mechanism: Ligands like glucose and other molecule activate receptors directly or by the passage through channels (Na+).
  • Sour senses are based on ion channel sensitivity to H+ ions.
  • Salty sensations rely on Na+ channel activation.
  • Sweet, bitter, and umami involve G-protein coupled receptors, leading to second messenger cascades (cAMP, IP3) and calcium release.

Homeostatic Control of Electrolytes

  • Maintaining electrolytes (like sodium and potassium) is critical for cell function and preventing issues such as overexcitation.
  • The balance of sodium is significant for extracellular fluid osmolarity and cellular function.
  • Taste plays a role in monitoring electrolyte levels and guiding behaviors related to acquiring or excreting needed compounds.

Central Processing of Taste Signals

  • Taste signals are relayed from the taste buds to the medulla oblongata, where they synapse with cranial nerve fibers.
  • Taste information progresses: solitary tract, VPM of the thalamus, gustatory cortex.
  • Different neural pathways are used for each taste's perception
  • Taste pathways involve a central convergence of multiple taste cells for an integrated experience.
  • Certain types of cells have specificities, but the actual experience is a resulting mix based on overall activity, which is computed by the brain.

Taste Perception Variations

  • Taste perception can vary based on age, with acuity often decreasing after 60.
  • Bitter often remains a sharp taste sense.

Taste Synergies

  • Taste sensations are not independent. Interactions between tastes affect perceived flavor.
  • One taste can enhance or suppress others in various ways.
  • The interplay between different taste qualities contributes to complex flavor perception.
  • The interaction of temperature and taste further impacts flavor complexity.

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