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Questions and Answers
Taste sensory cells transmit information via synapses to sensory fibers within the taste bud.
Taste sensory cells transmit information via synapses to sensory fibers within the taste bud.
True (A)
The primary gustative cortex is responsible for interpreting the quantity of food rather than the quality.
The primary gustative cortex is responsible for interpreting the quantity of food rather than the quality.
False (B)
Bitter is the least reactive taste receptor as age increases.
Bitter is the least reactive taste receptor as age increases.
False (B)
The VPM of thalamus plays a role in connecting taste information to cortical areas responsible for taste perception.
The VPM of thalamus plays a role in connecting taste information to cortical areas responsible for taste perception.
Chewing food has no effect on the perception of its taste before and after the process.
Chewing food has no effect on the perception of its taste before and after the process.
Sour taste corresponds to the presence of glucose.
Sour taste corresponds to the presence of glucose.
Taste receptor cells are primarily responsible for converting chemical stimuli into electrical signals.
Taste receptor cells are primarily responsible for converting chemical stimuli into electrical signals.
Calcium concentration is decreased during taste cell depolarization.
Calcium concentration is decreased during taste cell depolarization.
An imbalance of sodium ions poses a higher risk than an imbalance of potassium ions.
An imbalance of sodium ions poses a higher risk than an imbalance of potassium ions.
Umami taste is linked to the presence of hydrogen ions.
Umami taste is linked to the presence of hydrogen ions.
Taste is considered a special sensory organ for the skeletal system.
Taste is considered a special sensory organ for the skeletal system.
Sweet taste receptors utilize a G protein-coupled mechanism to transduce taste information.
Sweet taste receptors utilize a G protein-coupled mechanism to transduce taste information.
Taste receptor cells can respond to multiple substances simultaneously.
Taste receptor cells can respond to multiple substances simultaneously.
The osmotic equilibrium is primarily governed by sodium ions alone.
The osmotic equilibrium is primarily governed by sodium ions alone.
Taste buds are exclusively located in the tongue and do not exist in the pharynx.
Taste buds are exclusively located in the tongue and do not exist in the pharynx.
Circumvallate papillae contain the highest concentration of taste buds among the three types of papillae.
Circumvallate papillae contain the highest concentration of taste buds among the three types of papillae.
Fungiform papillae are predominantly found in the posterior part of the tongue.
Fungiform papillae are predominantly found in the posterior part of the tongue.
Taste buds regenerate every 10-15 days through the differentiation of supporting cells.
Taste buds regenerate every 10-15 days through the differentiation of supporting cells.
Chemoceptors in taste buds respond to an infinite variety of different substrates.
Chemoceptors in taste buds respond to an infinite variety of different substrates.
The apical portion of taste buds is responsible for the contact with the oral cavity fluids.
The apical portion of taste buds is responsible for the contact with the oral cavity fluids.
Foliate papillae contain no taste buds in their structure.
Foliate papillae contain no taste buds in their structure.
The 'Across neuron' hypothesis suggests that each receptor responds exclusively to a single type of taste.
The 'Across neuron' hypothesis suggests that each receptor responds exclusively to a single type of taste.
Cell 1 in the experiment solely responds to sodium chloride.
Cell 1 in the experiment solely responds to sodium chloride.
The principles of the 'Labelled line' theory are based on the overall computation of brain analysis rather than individual taste receptors.
The principles of the 'Labelled line' theory are based on the overall computation of brain analysis rather than individual taste receptors.
Chorda tympani fibers exhibit different response profiles to taste stimuli based on their sensitivity to temperature and taste profiles.
Chorda tympani fibers exhibit different response profiles to taste stimuli based on their sensitivity to temperature and taste profiles.
In the 'Labelled line' theory, a single gustatory neuron can represent multiple sensory attributes at once.
In the 'Labelled line' theory, a single gustatory neuron can represent multiple sensory attributes at once.
The activation of Axon 3 primarily leads to the detection of sour taste.
The activation of Axon 3 primarily leads to the detection of sour taste.
The threshold for activation differs among the fibers based on the type of substrate they are sensitive to.
The threshold for activation differs among the fibers based on the type of substrate they are sensitive to.
Fibers classified as sodium chloride-best can also be sensitive to bitterness according to the experimental findings.
Fibers classified as sodium chloride-best can also be sensitive to bitterness according to the experimental findings.
The 'Across neuron' hypothesis emphasizes the individual properties of each receptor rather than the combined analysis of group responses.
The 'Across neuron' hypothesis emphasizes the individual properties of each receptor rather than the combined analysis of group responses.
The discharge of chorda tympani fibers decreases significantly with increased sensitivity to salty stimuli.
The discharge of chorda tympani fibers decreases significantly with increased sensitivity to salty stimuli.
Salivation in response to food can occur just from looking at it.
Salivation in response to food can occur just from looking at it.
The T1R2 and T1R3 genes are responsible for encoding sweet receptors in humans.
The T1R2 and T1R3 genes are responsible for encoding sweet receptors in humans.
Bitter taste receptors are less sensitive than sweet taste receptors.
Bitter taste receptors are less sensitive than sweet taste receptors.
Umami taste is primarily associated with the presence of citric acid.
Umami taste is primarily associated with the presence of citric acid.
Different areas of the tongue exclusively detect certain tastes, such as sweet at the tip and bitter at the back.
Different areas of the tongue exclusively detect certain tastes, such as sweet at the tip and bitter at the back.
Chemosensory transduction begins in the basal domain of taste cells.
Chemosensory transduction begins in the basal domain of taste cells.
The transduction mechanism for taste includes both G-protein mediated activation and direct occlusion of K+ channels.
The transduction mechanism for taste includes both G-protein mediated activation and direct occlusion of K+ channels.
The neurotransmitter serotonin is released in the taste transduction process.
The neurotransmitter serotonin is released in the taste transduction process.
Sweetness is predominantly detected through a G-protein-independent signaling pathway.
Sweetness is predominantly detected through a G-protein-independent signaling pathway.
Taste buds can only respond to the five basic taste categories: salty, sour, sweet, bitter, and umami.
Taste buds can only respond to the five basic taste categories: salty, sour, sweet, bitter, and umami.
Flashcards
Taste buds
Taste buds
Small sensory organs found in the tongue, pharynx, epiglottis, and upper esophagus, responsible for detecting taste.
Papillae
Papillae
Clusters of taste buds on the tongue, categorized by their shape and location.
Fungiform Papillae
Fungiform Papillae
Mushroom-shaped papillae found mainly on the anterior 2/3 of the tongue.
Circumvallate Papillae
Circumvallate Papillae
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Foliate Papillae
Foliate Papillae
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Taste Cells
Taste Cells
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Taste Substrates
Taste Substrates
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Salty Taste
Salty Taste
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Sour Taste
Sour Taste
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Sweet Taste
Sweet Taste
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Umami
Umami
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Bitter Taste
Bitter Taste
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Salt Taste Receptor Cells
Salt Taste Receptor Cells
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Sour Taste Receptor Cells
Sour Taste Receptor Cells
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Sweet Taste Receptor Cells
Sweet Taste Receptor Cells
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Umami Taste Receptor Cells
Umami Taste Receptor Cells
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Defensive salivation
Defensive salivation
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Umami taste
Umami taste
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Taste transduction
Taste transduction
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Serotonin in taste
Serotonin in taste
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Taste cell domains
Taste cell domains
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Taste regions
Taste regions
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Taste sensitivity
Taste sensitivity
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Tastant
Tastant
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Flavor perception as a mosaic
Flavor perception as a mosaic
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Polymodal taste receptors
Polymodal taste receptors
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Taste signal pathway
Taste signal pathway
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Hierarchical taste processing
Hierarchical taste processing
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Taste synergies
Taste synergies
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Labelled Line Theory
Labelled Line Theory
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Across Neuron Hypothesis
Across Neuron Hypothesis
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Receptor Tuning
Receptor Tuning
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Threshold
Threshold
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Response Profile
Response Profile
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Brain Computation
Brain Computation
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Tuning Curves
Tuning Curves
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Taste Center
Taste Center
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Taste Alchemy
Taste Alchemy
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Gustatory Pathway
Gustatory Pathway
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Study Notes
Taste Bud Anatomy and Function
- Taste buds, sensory organs containing receptors, are located on the tongue, pharynx, epiglottis, and upper esophagus.
- They cluster in papillae, specific structures on the tongue's surface.
- Each taste bud consists of basal cells, taste cells (receptors), and supporting cells. Taste pores allow taste cells to interact with food substances in the mouth.
- Different papillae types include fungiform (25%), circumvallate (50%), and foliate (25%), each with distinct shapes and distributions across the tongue.
- Fungiform papillae are concentrated at the tongue tip, circumvallate papillae are located at the back, and foliate papillae are in the posterior lateral tongue areas.
- Despite shape variations, all papillae contain taste buds.
- Chemical stimuli initially interact with receptors on fungiform papillae, followed by foliate and then circumvallate papillae.
Taste Bud Structure and Function
- Taste buds have an onion-like shape, with the apical portion exposed to the oral cavity fluid.
- Taste cells are second-order receptors which do not produce action potentials; instead, they release neurotransmitters that activate afferent nerve fibers.
- Supporting cells secrete substances within the taste bud.
- Basal cells are a reservoir and can differentiate into new taste cells for continuous regeneration approximately every 10-15 days.
Types of Taste Stimuli
- Taste receptors are chemoreceptors reacting to specific classes of molecules; not an infinite variety of stimuli.
- These trigger specific taste sensations categorized as: sour, salty, sweet, bitter, and umami.
- Sour: related to hydrogen ion concentration (pH).
- Salty: sodium ions sensed.
- Sweet: glucose and other molecules.
- Bitter: diverse compounds like acids, salts, alkaloids.
- Umami: due to glutamate interaction.
Mechanisms of Taste Transduction
- Taste cells transduce chemical stimuli into electrical signals.
- This action is based on a ligand to receptor binding mechanism: Ligands like glucose and other molecule activate receptors directly or by the passage through channels (Na+).
- Sour senses are based on ion channel sensitivity to H+ ions.
- Salty sensations rely on Na+ channel activation.
- Sweet, bitter, and umami involve G-protein coupled receptors, leading to second messenger cascades (cAMP, IP3) and calcium release.
Homeostatic Control of Electrolytes
- Maintaining electrolytes (like sodium and potassium) is critical for cell function and preventing issues such as overexcitation.
- The balance of sodium is significant for extracellular fluid osmolarity and cellular function.
- Taste plays a role in monitoring electrolyte levels and guiding behaviors related to acquiring or excreting needed compounds.
Central Processing of Taste Signals
- Taste signals are relayed from the taste buds to the medulla oblongata, where they synapse with cranial nerve fibers.
- Taste information progresses: solitary tract, VPM of the thalamus, gustatory cortex.
- Different neural pathways are used for each taste's perception
- Taste pathways involve a central convergence of multiple taste cells for an integrated experience.
- Certain types of cells have specificities, but the actual experience is a resulting mix based on overall activity, which is computed by the brain.
Taste Perception Variations
- Taste perception can vary based on age, with acuity often decreasing after 60.
- Bitter often remains a sharp taste sense.
Taste Synergies
- Taste sensations are not independent. Interactions between tastes affect perceived flavor.
- One taste can enhance or suppress others in various ways.
- The interplay between different taste qualities contributes to complex flavor perception.
- The interaction of temperature and taste further impacts flavor complexity.
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