Tak Wah Mak's Contributions to Immunology

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Questions and Answers

What significant discovery did Tak Wah Mak make regarding T-cells in 1983?

  • T-cells can produce antibodies directly.
  • T-cells solely recognize bacterial infections.
  • T-cells require activation by macrophages.
  • T-cell receptors have a unique genetic sequence. (correct)

In which year did Tak Wah Mak publish his findings on human T-cell receptors in the Nature journal?

  • 1982
  • 1985
  • 1990
  • 1984 (correct)

What type of cancer did Tak Wah Mak identify a chemical to block the fuel supply for in 1999?

  • Lymphoma
  • Lung cancer
  • Breast cancer
  • Hodgkin's lymphoma (correct)

Which institution did Tak Wah Mak accept a fellowship at in 1972?

<p>Ontario Cancer Institute (D)</p> Signup and view all the answers

Which aspect of cancer research did Tak Wah Mak utilize molecular techniques for?

<p>Understanding immune responses to cancer cells. (A)</p> Signup and view all the answers

Before entering his field of immunology, what degree did Tak Wah Mak earn?

<p>PhD in Biochemistry (C)</p> Signup and view all the answers

What was one of Mak's early focuses in genetic research during the late 1980s?

<p>Isolating genetic functions related to cancer. (D)</p> Signup and view all the answers

What was the primary impact of Tak Wah Mak's discovery regarding T-cell receptors?

<p>It advanced the understanding of immune system functionality. (A)</p> Signup and view all the answers

Flashcards

T-cell receptor genes

The genes that instruct the creation of receptors on T-cells, which recognize and bind to specific antigens (foreign substances).

Antigens

Foreign substances that trigger an immune response.

T-cells

A type of white blood cell that plays a crucial role in the body's immune response.

Immune System

The body's defense system against foreign substances and diseases.

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Molecular Techniques

Methods for studying the structure and function of molecules.

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Hodgkin's Lymphoma

A type of cancer affecting the lymphatic system.

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Genetic Research (Immunology/Cancer)

Research on genetic factors that lead to and influence how immunity fights cancer.

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1983 breakthrough

Dr. Mak discovered the unique genetic sequence of T-cell receptors.

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1984 publication

Findings about the genetic encoding of human T-cell receptors were published in a journal.

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1999 chemical finding

Dr. Mak identified a chemical that could cut off the fuel supply to Hodgkin's lymphoma.

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