Lymphoma and Immunology Basics
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Questions and Answers

What is the main characteristic of lymphoma?

  • It originates in the gastrointestinal tract
  • It affects the lymphatic system (correct)
  • It is a type of leukemia
  • It primarily affects the bone marrow

What are the two main types of lymphoma?

  • Acute lymphoblastic lymphoma and chronic lymphocytic lymphoma
  • Burkitt lymphoma and T-cell lymphoma
  • Follicular lymphoma and mantle cell lymphoma
  • Hodgkin lymphoma and nonHodgkin lymphoma (correct)

What are proto-oncogenes responsible for in normal cells?

  • Causing cell death
  • Inducing apoptosis in cancer cells
  • Preventing cancer from developing
  • Regulating cell growth and division (correct)

What is the annual incidence of Hodgkin lymphoma in the western world?

<p>3 cases per 100000 person (A)</p> Signup and view all the answers

What is the contagious spread characteristic of Hodgkin lymphoma?

<p>It spreads through the peripheral lymph nodes (A)</p> Signup and view all the answers

What is the key mechanism for cell death mentioned in the text?

<p>Mitochondrial permeability transition-driven necrosis (C)</p> Signup and view all the answers

What is the most common type of Hodgkin lymphoma?

<p>Nodular sclerosis (C)</p> Signup and view all the answers

Which virus is found to infect B-cells and contribute to the pathogenesis of Hodgkin lymphoma?

<p>Epstein-Barr virus (EBV) (B)</p> Signup and view all the answers

What contributes to the conversion of normal B-cells to malignant HRS cells in Hodgkin lymphoma?

<p>Expression of hematopoietic stem cells (HSCs) key transcription factors (A)</p> Signup and view all the answers

What is the key mechanism in the survival of HRS cells in Hodgkin lymphoma?

<p>Ability to secrete different cytokines and chemokines (A)</p> Signup and view all the answers

What percentage of tumors associated with Hodgkin lymphoma is made up of activated normal immune cells?

<p>99% (C)</p> Signup and view all the answers

Which type of lymphoma is characterized by the absence of HRS cells and is considered less common and more dangerous than Hodgkin lymphoma?

<p>B-cell derived non-Hodgkin lymphoma (NHL) (C)</p> Signup and view all the answers

What are the signs and symptoms commonly associated with lymphoma?

<p>Unexplained fever and swollen abdomen (B)</p> Signup and view all the answers

What advanced test can determine if lymphoma cells are present and what types of cells are involved?

<p>Positron emission tomography (PET) scan (C)</p> Signup and view all the answers

In which type of biopsy procedure, all or part of a lymph node is removed for laboratory testing?

<p>Excisional biopsy (B)</p> Signup and view all the answers

What should your doctor check for during a physical exam for diagnosing lymphoma?

<p>Swollen lymph nodes and swollen spleen or liver (A)</p> Signup and view all the answers

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