Tak Wah Mak and Pulsars Quiz

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Questions and Answers

What significant finding about T-cells did Tak Wah Mak publish in March 1984?

  • The chemical structure of T-cell receptors.
  • The role of T-cells in autoimmune diseases.
  • The interaction between T-cells and cancer cells.
  • The genetic encoding of human T-cell receptors. (correct)

In what year did Tak Wah Mak isolate genetic functions for cancer using mice experiments?

  • 1999
  • 1992
  • 1984
  • 1988 (correct)

What type of cancer treatment did Tak Wah Mak identify in 1999?

  • A new vaccine for breast cancer.
  • A method to enhance chemotherapy effectiveness.
  • A cure for leukemia.
  • A chemical to block the fuel supply to Hodgkin's lymphoma. (correct)

What was Tak Wah Mak's primary contribution to our understanding of T-cells?

<p>Identifying the unique genetic sequence of T-cell receptors. (A)</p> Signup and view all the answers

Where did Tak Wah Mak obtain his PhD in Biochemistry?

<p>University of Alberta, Canada (B)</p> Signup and view all the answers

What defines a pulsar as a type of celestial object?

<p>It rotates rapidly and emits pulses of radiation. (C)</p> Signup and view all the answers

What was the playful working title for the pulsars before it was officially named in 1968?

<p>Little Green Men-1 (B)</p> Signup and view all the answers

Which prestigious honor was awarded to Jocelyn Bell Burnell in 2007?

<p>Dame Commander of the British Empire (D)</p> Signup and view all the answers

Who supervised Jocelyn Bell Burnell during her research that led to the discovery of pulsars?

<p>Antony Hewish (D)</p> Signup and view all the answers

What was a significant outcome of the initial observations of the radio waves detected by the telescopes?

<p>They were thought to be signals from extraterrestrial life. (D)</p> Signup and view all the answers

What significant discovery did Jocelyn Bell Burnell make in November 1967?

<p>Pulsating radio waves from a fixed point in space (D)</p> Signup and view all the answers

Which accomplishment is NOT associated with Jocelyn Bell Burnell?

<p>Receiving the Nobel Prize (A)</p> Signup and view all the answers

What area of research is Tak Wah Mak primarily known for?

<p>Immunology and molecular biology (B)</p> Signup and view all the answers

What breakthrough in understanding did Tak Wah Mak's research lead to?

<p>The process behind how T-cells recognize antigens (C)</p> Signup and view all the answers

In which year was Jocelyn Bell Burnell awarded the title of Dame Commander of the British Empire?

<p>2007 (B)</p> Signup and view all the answers

Flashcards

Jocelyn Bell Burnell

Pioneering scientist who discovered pulsars, a type of rapidly rotating neutron star.

Pulsar

A rapidly rotating neutron star, emitting pulses of radio waves.

1967

The year Jocelyn Bell Burnell discovered pulsars.

Radio Telescope

Device used to detect radio waves from space.

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Neutron Star

A highly dense star remnant from a supernova.

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1.337 seconds

The approximate rotation period of one of the first pulsars discovered.

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LGM-1

A playful, temporary name for the first pulsar discovered.

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PhD Thesis

A long research project for a PhD degree.

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Twinkling quasars

Bell's PhD thesis subject; a fascinating study of quasars.

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Antony Hewish

Supervisor who reported Bell's discovery and later received a Nobel Prize for this contribution.

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Tak Wah Mak's 1984 Nature finding

Detailed the genetic encoding of human T-cell receptors; a key step in understanding the immune system.

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T-cell receptors

Proteins on T-cells that recognize foreign substances (antigens) in the body.

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Hodgkin's lymphoma

A type of cancer affecting the lymphatic system.

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Genetic encoding of T-cells

The unique sequence of genes that make up T-cell receptors, allowing them to recognize specific targets.

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Molecular biologist/immunologist

A scientist studying the molecules that make up living things, especially the immune response.

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1999 chemical discovery

Identified a chemical to stop the energy supply of Hodgkin's lymphoma.

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Genetic functions in cancer & immunology

Understanding how genes contribute to cancer and the immune response, using mouse models.

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Fellow, Ontario Cancer Institute (1972)

Position at cancer research institute, after PhD completion.

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Jocelyn Bell Burnell's discovery

Pulsars, rapidly rotating neutron stars emitting radio waves.

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Pulsar rotation period

About 1.337 seconds for one of the first discovered.

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Bell Burnell's Contribution

First observed and named pulsars, helping understand neutron stars.

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Tak Wah Mak's Field

Immunologist and molecular biologist studying the immune system and cancer.

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T-cell receptors

Proteins on T-cells enabling recognition of specific antigens.

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Mak's cancer research

Identified a chemical to target Hodgkin's lymphoma cells.

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Nobel Prize (indirect)

Antony Hewish, not Bell Burnell, received the Nobel Prize for the pulsar discovery initially.

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Mak's research impact

Understanding how T-cells recognize antigens led to better understanding of immunity and cancer.

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1972

Tak Wah Mak became a fellow at Ontario Cancer Institute.

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