Pioneering Scientists: Bell Burnell & Tak Wah Mak
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Questions and Answers

What year was Jocelyn Bell Burnell awarded the title of Dame Commander of the British Empire (DBE)?

  • 1974
  • 1967
  • 1988
  • 2007 (correct)

Which significant term was introduced in 1968 due to Jocelyn Bell Burnell's discovery?

  • Neutron star
  • Radio wave
  • Quasar
  • Pulsar (correct)

What unique genetic sequence did Tak Wah Mak discover in 1983?

  • Antibody recognition sequence
  • Sequence responsible for cancer cell mutation
  • T-cell receptor sequence (correct)
  • Cytokine production sequence

In which year did Antony Hewish receive the Nobel Prize related to Jocelyn Bell Burnell's work?

<p>1974 (C)</p> Signup and view all the answers

What was the main focus of Tak Wah Mak's research throughout his career?

<p>Cancer immunology (B)</p> Signup and view all the answers

What did Jocelyn Bell Burnell's instruments detect in November 1967?

<p>Pulsating radio waves (A)</p> Signup and view all the answers

Which type of cancer did Tak Wah Mak identify a chemical to block the fuel supply for?

<p>Hodgkin’s lymphoma (B)</p> Signup and view all the answers

Where did Tak Wah Mak complete his PhD in biochemistry?

<p>University of Alberta (D)</p> Signup and view all the answers

Flashcards

What is a pulsar?

A celestial object that emits pulses of electromagnetic radiation at regular intervals.

Who discovered the first pulsar and who received the Nobel Prize?

Jocelyn Bell Burnell discovered the first pulsar in 1967. Antony Hewish and Bell Burnell published the findings in Nature, but only Hewish received the Nobel Prize in 1974.

What are T-cells and what did Tak Wah Mak discover about them?

T-cells are white blood cells that recognize antigens, which are molecules foreign to the body. Tak Wah Mak discovered that T-cell receptors have a unique genetic sequence.

What is antigen recognition and how did Mak's discovery help?

Antigen recognition is the ability of the immune system to distinguish between self and non-self. Tak Wah Mak's discovery of the T-cell receptor's unique genetic sequence helped scientists understand how the immune system recognizes antigens.

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Where was Jocelyn Bell Burnell when she made her discovery?

In the late 1960s, Jocelyn Bell Burnell was a graduate student at Cambridge University.

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Where was Tak Wah Mak born and educated?

Tak Wah Mak was born in China and studied at the University of Wisconsin and the University of Alberta.

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What was the impact of the pulsar discovery?

The discovery of the pulsar opened up new avenues for understanding neutron stars and the physics of extreme gravity.

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What was the impact of Tak Wah Mak's research?

Tak Wah Mak's research on T-cell receptors has had a significant impact on the understanding and treatment of immune-system diseases.

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Study Notes

Jocelyn Bell Burnell

  • First scientist to detect pulsars
  • Opened a new branch of astrophysics
  • Born in Belfast, Northern Ireland
  • Developed a flair for science at school
  • Resolved to work in astronomy
  • Graduated from Glasgow University in 1965
  • PhD thesis on twinkling quasars at Cambridge University
  • Helped design and build radio telescopes
  • Discovered pulsars in November 1967
  • Unexpected radio waves pulsating every 1.337 seconds
  • Similar signals detected in other parts of space
  • Concluded radio waves from a rapidly rotating, strongly magnetized neutron star (pulsar)
  • Coined the term "pulsar" in 1968

Tak Wah Mak

  • Immunologist and molecular biologist
  • Solved a longstanding problem in immunology
  • Discovered how T-cells recognize antigens
  • Breakthrough in 1983
  • T-cells recognize antigens using unique genetic sequences
  • Studied at the University of Wisconsin and the University of Alberta
  • Discovered the genetic sequence of T-cell receptors
  • Opened up a new chapter in the study and treatment of immune-system diseases
  • Applied molecular techniques to learn more about immune responses to cancer
  • Quote: "We can never give up the fight against cancer"

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Explore the groundbreaking contributions of Jocelyn Bell Burnell, who discovered pulsars, and Tak Wah Mak, who advanced our understanding of T-cell recognition in immunology. This quiz highlights their remarkable achievements and the impact they had on their respective fields. Test your knowledge about their lives, discoveries, and significance in science.

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