Podcast
Questions and Answers
What is the primary function of Regulatory T (TR) cells in the immune system?
What is the primary function of Regulatory T (TR) cells in the immune system?
- Promote multiplication and cytokine secretion by other T cells
- Activate memory cells in cellular immunity
- Destroy diseased or foreign cells directly
- Limit immune response by inhibiting multiplication and cytokine secretion by other T cells (correct)
What type of immunity involves T lymphocytes directly attacking and destroying diseased or foreign cells?
What type of immunity involves T lymphocytes directly attacking and destroying diseased or foreign cells?
- Cellular immunity (correct)
- Passive immunity
- Humoral immunity
- Innate immunity
What is the role of Memory T (TM) cells in the immune system?
What is the role of Memory T (TM) cells in the immune system?
- Activate co-stimulation for T cell activation
- Inhibit the immune response by suppressing T cell activation
- Destroy antigens directly to prevent infection
- Recognize antigens and prevent them from causing disease in the future (correct)
What is the function of Antigen presenting cells (APC) in the immune response?
What is the function of Antigen presenting cells (APC) in the immune response?
Which type of T cells are activated by interaction with an MHC-I displayed antigen?
Which type of T cells are activated by interaction with an MHC-I displayed antigen?
What process involves the encounter, processing, and presentation of an antigen by an APC to T cells?
What process involves the encounter, processing, and presentation of an antigen by an APC to T cells?
What occurs when a T cell binds to an MHC protein displaying an epitope it recognizes?
What occurs when a T cell binds to an MHC protein displaying an epitope it recognizes?
Where are T lymphocytes (T cells) born?
Where are T lymphocytes (T cells) born?
Which cells test T cells by presenting self-antigens to them in the thymus?
Which cells test T cells by presenting self-antigens to them in the thymus?
What stimulates maturing T cells to develop surface antigen receptors in the thymus?
What stimulates maturing T cells to develop surface antigen receptors in the thymus?
What is the function of Helper T (TH) cells?
What is the function of Helper T (TH) cells?
What percentage of T cells that reach the thymus leave as immunocompetent T cells?
What percentage of T cells that reach the thymus leave as immunocompetent T cells?
What would happen if a T cell fails the test by reacting to self-antigens?
What would happen if a T cell fails the test by reacting to self-antigens?
Which stage comes after the deployment of naive T cells from the thymus?
Which stage comes after the deployment of naive T cells from the thymus?
What type of T cells are the 'effectors' of cellular immunity?
What type of T cells are the 'effectors' of cellular immunity?
What is the primary function of Regulatory T (TR) cells in the immune system?
What is the primary function of Regulatory T (TR) cells in the immune system?
What type of immunity involves T lymphocytes directly attacking and destroying diseased or foreign cells?
What type of immunity involves T lymphocytes directly attacking and destroying diseased or foreign cells?
What is the role of Memory T (TM) cells in the immune system?
What is the role of Memory T (TM) cells in the immune system?
What stimulates maturing T cells to develop surface antigen receptors in the thymus?
What stimulates maturing T cells to develop surface antigen receptors in the thymus?
What would happen if a T cell fails the test by reacting to self-antigens?
What would happen if a T cell fails the test by reacting to self-antigens?
What occurs when a T cell binds to an MHC protein displaying an epitope it recognizes?
What occurs when a T cell binds to an MHC protein displaying an epitope it recognizes?
Which stage comes after the deployment of naive T cells from the thymus?
Which stage comes after the deployment of naive T cells from the thymus?
What is the role of Helper T (TH) cells in the immune system?
What is the role of Helper T (TH) cells in the immune system?
What happens when a T cell fails the test by reacting to self-antigens?
What happens when a T cell fails the test by reacting to self-antigens?
Where do Naive T cells go after leaving the thymus?
Where do Naive T cells go after leaving the thymus?
What is the primary function of Cytotoxic T (TC) cells in the immune system?
What is the primary function of Cytotoxic T (TC) cells in the immune system?
Which cells test T cells by presenting self-antigens to them in the thymus?
Which cells test T cells by presenting self-antigens to them in the thymus?
What percentage of T cells that reach the thymus leave as immunocompetent T cells?
What percentage of T cells that reach the thymus leave as immunocompetent T cells?
What stimulates maturing T cells to develop surface antigen receptors in the thymus?
What stimulates maturing T cells to develop surface antigen receptors in the thymus?
What is the fate of T cells that fail the test due to inability to recognize self-antigens (positive selection)?
What is the fate of T cells that fail the test due to inability to recognize self-antigens (positive selection)?
_______ T cells inhibit multiplication and cytokine secretion by other T cells
_______ T cells inhibit multiplication and cytokine secretion by other T cells
_______ T cells are responsible for memory in cellular immunity
_______ T cells are responsible for memory in cellular immunity
________ immunity is a form of specific defense in which the T lymphocytes directly attack and destroy diseased or foreign cells
________ immunity is a form of specific defense in which the T lymphocytes directly attack and destroy diseased or foreign cells
Antigen presenting cells are required for ________ presentation
Antigen presenting cells are required for ________ presentation
MHC-I presents antigens to ________ T cells
MHC-I presents antigens to ________ T cells
MHC-II presents antigens to ________ T cells
MHC-II presents antigens to ________ T cells
T cell activation involves binding to MHC displaying an epitope that it ________
T cell activation involves binding to MHC displaying an epitope that it ________
T lymphocytes (T cells) life history involves three stages and three anatomical stations in the body – Born in the red bone marrow Dorn – Go to school in the ____________ school – Deployed to the lymphatic organs work
T lymphocytes (T cells) life history involves three stages and three anatomical stations in the body – Born in the red bone marrow Dorn – Go to school in the ____________ school – Deployed to the lymphatic organs work
Thymosins stimulate maturing T cells to develop surface antigen receptors, making them ____________ receptor
Thymosins stimulate maturing T cells to develop surface antigen receptors, making them ____________ receptor
Reticuloendothelial (RE) cells in the thymus test T cells by presenting self-antigens to them, acting as the final ____________
Reticuloendothelial (RE) cells in the thymus test T cells by presenting self-antigens to them, acting as the final ____________
Inability to recognize the RE cells, especially their MHC antigens, results in ____________ selection
Inability to recognize the RE cells, especially their MHC antigens, results in ____________ selection
Reacting to self-antigens leads to ____________ selection of T cells
Reacting to self-antigens leads to ____________ selection of T cells
2% of the T cells that reach the thymus leave as ____________ T cells
2% of the T cells that reach the thymus leave as ____________ T cells
Naive T cells leave the thymus and colonize lymphatic tissues and organs, becoming cells of cellular ____________
Naive T cells leave the thymus and colonize lymphatic tissues and organs, becoming cells of cellular ____________
Cytotoxic T (TC) cells are known as the 'Effectors' of cellular ____________
Cytotoxic T (TC) cells are known as the 'Effectors' of cellular ____________
T lymphocytes are born in the red bone marrow
T lymphocytes are born in the red bone marrow
Thymosins stimulate T cells to develop surface antigen receptors in the spleen
Thymosins stimulate T cells to develop surface antigen receptors in the spleen
Reticuloendothelial (RE) cells present self-antigens to test T cells in the thymus
Reticuloendothelial (RE) cells present self-antigens to test T cells in the thymus
Naive T cells leave the thymus and colonize lymphatic tissues and organs throughout the body
Naive T cells leave the thymus and colonize lymphatic tissues and organs throughout the body
Cytotoxic T cells are known as 'Effectors' of cellular immunity
Cytotoxic T cells are known as 'Effectors' of cellular immunity
Helper T cells promote B cell action and nonspecific immunity
Helper T cells promote B cell action and nonspecific immunity
Less than 2% of T cells that reach the thymus leave as immunocompetent T cells
Less than 2% of T cells that reach the thymus leave as immunocompetent T cells
Memory T cells are activated by interaction with MHC-II displayed antigens
Memory T cells are activated by interaction with MHC-II displayed antigens
Memory T cells are responsible for memory in humoral immunity.
Memory T cells are responsible for memory in humoral immunity.
Antigen presenting cells migrate to the nearest lymph node and present antigens to B cells.
Antigen presenting cells migrate to the nearest lymph node and present antigens to B cells.
Cytotoxic T cells are activated by interaction with MHC-II displayed antigens.
Cytotoxic T cells are activated by interaction with MHC-II displayed antigens.
Clonal selection is a process that occurs during T cell activation.
Clonal selection is a process that occurs during T cell activation.
Memory cells have a primary function of inhibiting multiplication of other T cells.
Memory cells have a primary function of inhibiting multiplication of other T cells.
Antigen presentation involves an APC encountering, processing, and presenting an antigen to T cells.
Antigen presentation involves an APC encountering, processing, and presenting an antigen to T cells.
Helper T cells are activated by co-stimulation during T cell activation.
Helper T cells are activated by co-stimulation during T cell activation.
What is the primary function of Regulatory T (TR) cells in the immune system?
What is the primary function of Regulatory T (TR) cells in the immune system?
What is the role of Memory T (TM) cells in the immune system?
What is the role of Memory T (TM) cells in the immune system?
Which type of immunity involves T lymphocytes directly attacking and destroying diseased or foreign cells?
Which type of immunity involves T lymphocytes directly attacking and destroying diseased or foreign cells?
What is the process that occurs when a T cell binds to an MHC protein displaying an epitope it recognizes?
What is the process that occurs when a T cell binds to an MHC protein displaying an epitope it recognizes?
Where are T lymphocytes (T cells) born?
Where are T lymphocytes (T cells) born?
What occurs when a T cell fails the test by reacting to self-antigens in the thymus?
What occurs when a T cell fails the test by reacting to self-antigens in the thymus?
'Memory' T cells are responsible for:
'Memory' T cells are responsible for:
What is the primary function of Helper T (TH) cells in the immune system?
What is the primary function of Helper T (TH) cells in the immune system?
What is the outcome if a T cell reacts to self-antigens during testing in the thymus?
What is the outcome if a T cell reacts to self-antigens during testing in the thymus?
Where do naive T cells go after leaving the thymus?
Where do naive T cells go after leaving the thymus?
What occurs during positive selection in the thymus?
What occurs during positive selection in the thymus?
What is the significance of 2% of T cells reaching immunocompetence in the thymus?
What is the significance of 2% of T cells reaching immunocompetence in the thymus?
What is the primary role of Regulatory T (TR) cells in the immune system?
What is the primary role of Regulatory T (TR) cells in the immune system?
Which anatomical station do T cells go to after being 'born' in the red bone marrow?
Which anatomical station do T cells go to after being 'born' in the red bone marrow?
What is the main function of Cytotoxic T (TC) cells in cellular immunity?
What is the main function of Cytotoxic T (TC) cells in cellular immunity?