T-Cell Maturation: Events in the Thymus

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What is the primary function of Th-1 cells during infections?

Involved in delayed hypersensitivity reactions against mycobacterial infections

What is the purpose of negative selection in the thymus?

To remove T cells carrying high affinity antigen receptors for self-antigens

What is the primary function of Th-2 cells?

Synthesizing gamma interferon to control pyogenic bacterial infections

What is the role of interleukin-2 in T-cell maturation?

Enhanced T-cell maturation

What is the characteristic of superantigens in the context of T-cell maturation?

They play an important role in both positive and negative selection

What is the primary function of Th-17 cells?

Producing interleukin-17 to stimulate CTLs

Which type of T cells retains the CD4 coreceptor?

T cells specific for MHC class I proteins

What is the outcome for T cells carrying high-affinity antigen receptors for self-antigens?

They undergo negative selection

Which cytokine is involved in the multiplication of CD8+ CTLs and NK cells?

IL-2

Which of the following statements about IL-12 is accurate?

It is produced by eosinophils and enhances the production of cells that mediate immediate hypersensitivity

What is the primary function of chemokines?

To attract immune cells to sites of inflammation

What is the role of chemokines in the inflammatory response?

They attract neutrophils to the site of bacterial infection

What is the result of chemokines inducing gene switching in B cells?

An increase in the amount of IgE synthesized

What is the diagnosis of the patient based on the examination results?

Kaposi's sarcoma

What is the recommended treatment for the patient based on the examination results?

Antiretroviral drugs and consultation with an oncologist

What is the significance of the CD4 count below 120 cl/ml in the patient's examination results?

It indicates the presence of HIV infection

What is the significance of the HV viral load of over 1100,000 copies/ml in the patient's examination results?

It indicates a high level of HIV replication

Test your knowledge on the events that occur in the thymus during T-cell maturation. Learn about the role of Th-2 cells and gamma interferon in controlling infections. Evaluate your understanding of the immune system and its functions.

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