Lecture 06: T-cells and B-cell activation [MCQ 1]

<p>Th cells release cytokines that stimulate B-cell proliferation and differentiation (C)</p> Signup and view all the answers

<p>4-7 days (C)</p> Signup and view all the answers

<p>To activate complement pathways, enhancing immune cell activity (D)</p> Signup and view all the answers

<p>All of the above (D)</p> Signup and view all the answers

<p>T-cells require antigen presented by antigen-presenting cells (APCs), while B-cells can directly bind free antigen (C)</p> Signup and view all the answers

<p>To receive signals from other immune cells, such as T helper cells, that are necessary for full activation (A)</p> Signup and view all the answers

<p>By their ability to bind to specific molecules within the lymph node (C)</p> Signup and view all the answers

<p>MHC II molecules present antigens derived from extracellular pathogens to helper T cells (Th cells). (B)</p> Signup and view all the answers

<p>Perforin and granzyme are proteins produced by cytotoxic T cells to induce apoptosis in infected cells. (D)</p> Signup and view all the answers

<p>Th cells regulate the activity of other immune cells, including B cells and cytotoxic T cells. (C)</p> Signup and view all the answers

<p>HIV infection impairs the function of helper T cells, leading to a severely compromised immune system. (C)</p> Signup and view all the answers

<p>Clonal expansion involves the proliferation of activated T cells, resulting in a large population of identical cells specific for the same antigen. (C)</p> Signup and view all the answers

<p>MHC I molecules are expressed on all nucleated cells, while MHC II molecules are only expressed on antigen-presenting cells. (C), MHC I molecules present antigens derived from intracellular pathogens, while MHC II molecules present antigens derived from extracellular pathogens. (D)</p> Signup and view all the answers

<p>Direct killing of infected cells by releasing cytotoxic molecules. (A)</p> Signup and view all the answers

<p>DCs present antigens to helper T cells, initiating the adaptive immune response. (A)</p> Signup and view all the answers

<p>Naive T cells have not encountered their specific antigen, while effector T cells have been activated and can perform their function. (A)</p> Signup and view all the answers

<p>Antigen presentation is the process by which cells display fragments of foreign proteins on their surface for recognition by T cells. (B)</p> Signup and view all the answers

White blood cells that mature in the thymus and respond to antigens.

Protein on T-cells that recognizes specific antigens on infected cells.

T-cells that kill cancerous or infected cells directly.

T-cells that activate other immune cells through cytokines.

Molecules on cell surfaces that present antigens to T-cells.

Presents antigens from all nucleated cells to Cytotoxic T cells.

Presents antigens from phagocytosed microbes to Helper T cells.

Rapid proliferation of T-cells after activation by antigen-presenting cells.

Process where cells display antigens on surface MHC to activate T-cells.

They enable B-cells to produce antibodies and stimulate Tc cells to proliferate.

T-cells recognize antigens presented by DC cells and become activated.

B-cells detect free antigens in lymph nodes and can become activated.

Antigens entering lymph nodes are sorted by molecular size.

Macrophages in lymph nodes handle viruses and large antigens.

After detecting antigens, B cells stay, undergo clonal selection, and prepare to produce antibodies.

T-cells proliferate into Tc and Th cells after recognizing specific antigens.

B-cells engulf antigens and present them via MHC II to Th cells.

Th cells are crucial for activating B-cells with the correct TCR.

Activated B-cells differentiate into plasma cells that produce antibodies.

B-cells can produce five classes of antibodies: IgG, IgA, IgM, IgE, IgD.