Systemic Lupus Erythematosus Overview
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Questions and Answers

What is the peak age at onset for systemic lupus erythematosus (SLE)?

  • Between 20 and 30 years (correct)
  • Between 50 and 60 years
  • Between 60 and 70 years
  • Between 40 and 50 years

What is the prevalence of systemic lupus erythematosus (SLE) in Caucasians?

  • 5%
  • 0.2%
  • 0.03% (correct)
  • 1%

What is the gender distribution among affected patients of systemic lupus erythematosus (SLE)?

  • 60% female, 40% male
  • 50% female, 50% male
  • 90% female (correct)
  • 90% male

What genetic factors are strongly associated with systemic lupus erythematosus (SLE)?

<p>Polymorphic variants at the HLA locus (A)</p> Signup and view all the answers

What is the prevalence of systemic lupus erythematosus (SLE) in Afro-Caribbeans?

<p>0.2% (C)</p> Signup and view all the answers

What is the characteristic feature of systemic lupus erythematosus (SLE) from an immunological standpoint?

<p>Autoantibody production (C)</p> Signup and view all the answers

Which age group has the peak age at onset for systemic lupus erythematosus (SLE)?

<p>20-30 years (B)</p> Signup and view all the answers

What is the cause of SLE from an immunological standpoint?

<p>Defects in apoptosis (D)</p> Signup and view all the answers

Which genetic factor is strongly associated with systemic lupus erythematosus (SLE)?

<p>HLA locus (B)</p> Signup and view all the answers

What is the gender distribution among affected patients of systemic lupus erythematosus (SLE)?

<p>90% female, 10% male (C)</p> Signup and view all the answers

What is the prevalence of systemic lupus erythematosus (SLE) in Afro-Caribbeans?

<p>0.2%</p> Signup and view all the answers

What is the main cause of the increased mortality in SLE patients?

<p>Premature cardiovascular disease</p> Signup and view all the answers

What is the role of genetic factors in systemic lupus erythematosus (SLE)?

<p>Genetic factors play an important role in SLE.</p> Signup and view all the answers

What is the characteristic feature of SLE from an immunological standpoint?

<p>Autoantibody production</p> Signup and view all the answers

What may cause SLE due to defects in apoptosis or in the clearance of apoptotic cells?

<p>Inappropriate exposure of intracellular antigens on the cell surface</p> Signup and view all the answers

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