Systemic Lupus Erythematosus Monitoring and Survival Rates
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Systemic Lupus Erythematosus Monitoring and Survival Rates

Learn about the lab tests used to monitor the course of Systemic Lupus Erythematosus (SLE), as well as factors that affect survival rates in SLE patients. Understand the significance of activity indices like ESR, complement levels, and various antibodies.

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@VeritableGeranium

Questions and Answers

Systemic lupus erythematosus (SLE) is a rare autoimmune disease.

False

The most common clinical manifestations of SLE are fatigue, fever, and weight loss.

True

Neurological symptoms, such as seizures and psychosis, are present in 60% of SLE patients.

True

Cardiovascular diseases are not a common complication of SLE.

<p>False</p> Signup and view all the answers

Polyarthritis is a rare manifestation of SLE, occurring in only 10% of patients.

<p>False</p> Signup and view all the answers

Diagnosing SLE is a straightforward process with clear-cut diagnostic criteria.

<p>False</p> Signup and view all the answers

The 5-year survival rate for patients with SLE is approximately 95%.

<p>True</p> Signup and view all the answers

Decreased complement levels are a sign of disease activity in SLE.

<p>True</p> Signup and view all the answers

Antiphospholipid antibodies are associated with a poor prognosis in SLE.

<p>True</p> Signup and view all the answers

Renal failure is the leading cause of death in patients with SLE.

<p>True</p> Signup and view all the answers

The goal of SLE treatment is to induce remission of acute flares and then maintain it, as well as prevent organ damage.

<p>True</p> Signup and view all the answers

Aggressive therapy with high-dose corticosteroids and a second immunosuppressive agent is recommended for SLE manifestations that are not reversible.

<p>False</p> Signup and view all the answers

Belimumab is a drug that inhibits B-cell activation and is used in the treatment of Systemic Lupus Erythematosus (SLE).

<p>True</p> Signup and view all the answers

Chronic discoid lupus erythematosus (DLE) is a variant of SLE that is limited to the skin and is characterized by circular, scaly, hyperpigmented rashes.

<p>True</p> Signup and view all the answers

Immunosuppressive agents like cyclophosphamide and mycophenolate mofetil are used in the treatment of serious kidney and central nervous system (CNS) involvement in SLE.

<p>True</p> Signup and view all the answers

Neonatal lupus is a condition where the mother's anti-SSA/Ro and anti-SSB/La antibodies affect the fetus, causing skin rash, liver problems, and low blood cell counts, but these symptoms persist throughout the child's life.

<p>False</p> Signup and view all the answers

Drug-induced lupus is a variant of SLE characterized by fever, malaise, arthritis/arthralgia, myalgia, serositis, and/or rash, but without kidney or CNS involvement.

<p>True</p> Signup and view all the answers

Hydroxychloroquine, an anti-malaria drug, is used in the treatment of SLE for managing joint pain and skin rashes.

<p>True</p> Signup and view all the answers

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