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Systemic lupus erythematosus (SLE) is a rare autoimmune disease.
False
The most common clinical manifestations of SLE are fatigue, fever, and weight loss.
True
Neurological symptoms, such as seizures and psychosis, are present in 60% of SLE patients.
True
Cardiovascular diseases are not a common complication of SLE.
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Polyarthritis is a rare manifestation of SLE, occurring in only 10% of patients.
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Diagnosing SLE is a straightforward process with clear-cut diagnostic criteria.
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The 5-year survival rate for patients with SLE is approximately 95%.
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Decreased complement levels are a sign of disease activity in SLE.
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Antiphospholipid antibodies are associated with a poor prognosis in SLE.
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Renal failure is the leading cause of death in patients with SLE.
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The goal of SLE treatment is to induce remission of acute flares and then maintain it, as well as prevent organ damage.
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Aggressive therapy with high-dose corticosteroids and a second immunosuppressive agent is recommended for SLE manifestations that are not reversible.
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Belimumab is a drug that inhibits B-cell activation and is used in the treatment of Systemic Lupus Erythematosus (SLE).
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Chronic discoid lupus erythematosus (DLE) is a variant of SLE that is limited to the skin and is characterized by circular, scaly, hyperpigmented rashes.
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Immunosuppressive agents like cyclophosphamide and mycophenolate mofetil are used in the treatment of serious kidney and central nervous system (CNS) involvement in SLE.
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Neonatal lupus is a condition where the mother's anti-SSA/Ro and anti-SSB/La antibodies affect the fetus, causing skin rash, liver problems, and low blood cell counts, but these symptoms persist throughout the child's life.
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Drug-induced lupus is a variant of SLE characterized by fever, malaise, arthritis/arthralgia, myalgia, serositis, and/or rash, but without kidney or CNS involvement.
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Hydroxychloroquine, an anti-malaria drug, is used in the treatment of SLE for managing joint pain and skin rashes.
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