Systemic Lupus Erythematosus Definition Quiz

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What is the age range most commonly affected by SLE?

6-16 years

40-70 years

20-40 years (correct)

60-80 years

Which population group shows a higher prevalence of SLE?

Native Indians (correct)

Asians

Africans

Europeans

In which setting is the prevalence of SLE higher?

Mountainous regions

Urban areas (correct)

Suburban areas

Rural areas

Which gender tends to have higher morbidity and mortality in SLE?

Males Signup and view all the answers

What is the current theory regarding the etiology of SLE?

Unclear and multifactorial Signup and view all the answers

Which environmental factor is considered a risk factor for SLE, especially in terms of disease severity?

Cigarette smoking Signup and view all the answers

What is the key characteristic of systemic lupus erythematosus?

Production of pathogenic autoantibodies Signup and view all the answers

Which statement is true regarding the presentation of systemic lupus erythematosus?

Varies from mild to severe organ involvement Signup and view all the answers

What factor contributes to the rising incidence of systemic lupus erythematosus over the last few decades?

Improved diagnostic capabilities Signup and view all the answers

Which group is more severely affected by systemic lupus erythematosus in terms of internal organ involvement?

Black individuals Signup and view all the answers

In systemic lupus erythematosus, which gender shows a higher susceptibility to the disease?

Females are more affected Signup and view all the answers

What is the major cause of mortality in systemic lupus erythematosus comparable to coronary artery disease?

Kidney involvement Signup and view all the answers

What is the most likely cause of thrombocytopenia in the text?

Combs positive Signup and view all the answers

Which condition is characterized by hemolytic normochromic normocytic anemia in the given text?

Anti-phospholipid syndrome Signup and view all the answers

What does a markedly elevated ESR value (>100) likely indicate in the text?

Kidney involvement Signup and view all the answers

Which test result is suggestive of lupus nephritis in the text?

Hematuria (>5 RBC/HPF) Signup and view all the answers

What are the significant findings associated with anti-phospholipid syndrome according to the text?

Recurrent abortions Signup and view all the answers

Which antibody is specifically mentioned to cross the placenta and potentially cause heart block in neonates in the text?

Congenital betamethasone antibodies Signup and view all the answers

What is a common symptom of photosensitivity in Discoid MALAR RASH?

Atrophic scarring Signup and view all the answers

Which of the following is NOT a typical symptom of Discoid RASH?

Raised malar eminences Signup and view all the answers

What is a common indicator of Renal involvement in the context of the text?

Proteinuria >0.5 g/d Signup and view all the answers

Which symptom would be a sign of Neurologic Disorders according to the text?

Psychosis without known causes Signup and view all the answers

What type of arthritis is associated with Lupus as per the given information?

Non-erosive arthritis Signup and view all the answers

What common hematological disorder is mentioned in the text as associated with Lupus?

Anemia and leukopenia Signup and view all the answers

What is thought to be the likely culprit for the preponderance of SLE amongst females?

Estrogen Signup and view all the answers

Which genetic factors have been implicated in the causation of SLE?

HLA DR2 and DR3 genes Signup and view all the answers

Which clinical manifestation is characteristic of SLE skin lesions?

Generalized erythema Signup and view all the answers

What is the primary mechanism contributing to Raynaud phenomenon in SLE?

Vasoconstriction Signup and view all the answers

Which complication can Ibuprofen potentially lead to in SLE patients?

Cranial neuropathy Signup and view all the answers

In SLE, what does CNS stand for in the context of clinical presentations?

Central Nervous System Signup and view all the answers

Which gastrointestinal symptom is commonly associated with SLE?

Dysphagia Signup and view all the answers