Podcast
Questions and Answers
What is the main advantage of Hb-based O2 carriers (HBOCs) over human blood?
What is the main advantage of Hb-based O2 carriers (HBOCs) over human blood?
- Carry oxygen only when Pao2 is more than 300 mm Hg
- Do not require type and crossmatch (correct)
- Transmit infectious viruses
- Require type and crossmatch
Which perfluoro compound carries three to four times more oxygen than Fluosol-DA?
Which perfluoro compound carries three to four times more oxygen than Fluosol-DA?
- Perfluorochemical emulsion
- Perfluorooctanoic acid
- Perfluorooctyl bromide (correct)
- Fluosol-DA
What characteristic is required by most HBOCs to prevent nephrotoxicity?
What characteristic is required by most HBOCs to prevent nephrotoxicity?
- Right shift in the O2 dissociation curve
- Low O2 affinity
- Stroma-free Hb (correct)
- High O2 affinity
Which synthetic blood product was initially approved for perfusion of ischemic tissues?
Which synthetic blood product was initially approved for perfusion of ischemic tissues?
What is the main issue with stroma-free Hb as mentioned in the text?
What is the main issue with stroma-free Hb as mentioned in the text?
What was a significant finding of Natanson and colleagues' meta-analysis on HBOCs?
What was a significant finding of Natanson and colleagues' meta-analysis on HBOCs?
What distinguishes Hemopure (HBOC-201) from human RBCs based on the text?
What distinguishes Hemopure (HBOC-201) from human RBCs based on the text?
What is the role of HBOCs according to the text?
What is the role of HBOCs according to the text?
What is one of the distinct procedures that autologous blood transfusion constitutes, according to the text?
What is one of the distinct procedures that autologous blood transfusion constitutes, according to the text?
What is one of the aims of autologous transfusion mentioned in the text?
What is one of the aims of autologous transfusion mentioned in the text?
What criterion must most donors meet prior to preoperative autologous donation according to the AABB?
What criterion must most donors meet prior to preoperative autologous donation according to the AABB?
What is the recommended time interval between repeated donations for preoperative autologous donation?
What is the recommended time interval between repeated donations for preoperative autologous donation?
Why is there a 72-hour interval required between the last donation and the time of surgery for preoperative autologous donation?
Why is there a 72-hour interval required between the last donation and the time of surgery for preoperative autologous donation?
According to the Hemoglobin and Iron Recovery Study (HEIRS), how long does it take for recovery of 80% red cell mass after preoperative autologous donation?
According to the Hemoglobin and Iron Recovery Study (HEIRS), how long does it take for recovery of 80% red cell mass after preoperative autologous donation?
What is the effect of preoperative autologous donation (PAD) on the risk of receiving a transfusion from any source?
What is the effect of preoperative autologous donation (PAD) on the risk of receiving a transfusion from any source?
Why are certain patient populations considered poor candidates for PAD?
Why are certain patient populations considered poor candidates for PAD?
How does the hospitalization rate post PAD compare between American Red Cross donors and allogenic donors?
How does the hospitalization rate post PAD compare between American Red Cross donors and allogenic donors?
In what way does PAD affect the hemoglobin levels compared to those who do not donate preoperatively?
In what way does PAD affect the hemoglobin levels compared to those who do not donate preoperatively?
which one is considered Contradictions to Participation in Autologous Blood Donation Programs
which one is considered Contradictions to Participation in Autologous Blood Donation Programs
How much RBC mass is saved by minimal ANH compared to a patient's blood volume?
How much RBC mass is saved by minimal ANH compared to a patient's blood volume?
What do retrospective data suggest about the impact of even mild ANH?
What do retrospective data suggest about the impact of even mild ANH?
In which type of surgeries has ANH been shown to decrease transfusion requirements according to randomized trials?
In which type of surgeries has ANH been shown to decrease transfusion requirements according to randomized trials?
How many allogenic blood units were patients who underwent ANH receiving compared to control groups on average?
How many allogenic blood units were patients who underwent ANH receiving compared to control groups on average?
What potential complication was observed in adult animal models receiving ANH transfusions?
What potential complication was observed in adult animal models receiving ANH transfusions?
What protective effect does ANH have specifically during cardiac surgery?
What protective effect does ANH have specifically during cardiac surgery?
What should be considered when making decisions about using ANH?
What should be considered when making decisions about using ANH?
What is the major benefit of Acute Normovolemic Hemodilution (ANH) mentioned in the text?
What is the major benefit of Acute Normovolemic Hemodilution (ANH) mentioned in the text?
What is the purpose of reversing the order of blood collection during ANH when reinfusing the sequestered blood?
What is the purpose of reversing the order of blood collection during ANH when reinfusing the sequestered blood?
What is the recommended storage temperature for collected blood during Acute Normovolemic Hemodilution (ANH), as mentioned in the text?
What is the recommended storage temperature for collected blood during Acute Normovolemic Hemodilution (ANH), as mentioned in the text?
How do thromboelastography (TEG) measurements differ between samples agitated during storage and those left stationary, according to the text?
How do thromboelastography (TEG) measurements differ between samples agitated during storage and those left stationary, according to the text?
What does the term 'intraoperative cell salvage' refer to?
What does the term 'intraoperative cell salvage' refer to?
What is a general indication for the use of cell salvage according to the AABB guidelines?
What is a general indication for the use of cell salvage according to the AABB guidelines?
Which anticoagulants are commonly used in the blood collection process of cell salvage?
Which anticoagulants are commonly used in the blood collection process of cell salvage?
When is cell salvage considered acceptable for use with patients who do not consent to allogeneic transfusions?
When is cell salvage considered acceptable for use with patients who do not consent to allogeneic transfusions?
What is one of the main purposes of intraoperative cell salvage during surgery?
What is one of the main purposes of intraoperative cell salvage during surgery?
Which scenario would make a patient a good candidate for cell salvage?
Which scenario would make a patient a good candidate for cell salvage?
What process separates the lower density plasma and anticoagulant fluid from the higher density RBCs in processing?
What process separates the lower density plasma and anticoagulant fluid from the higher density RBCs in processing?
Which component is collected at the bottom of the bowl during the processing of blood?
Which component is collected at the bottom of the bowl during the processing of blood?
What happen to the oxygen transport property of recovered RBCs ?
What happen to the oxygen transport property of recovered RBCs ?
What is a potential risk associated with reinfusion of salvaged blood?
What is a potential risk associated with reinfusion of salvaged blood?
What happens to the concentration of free hemoglobin in patients after receiving salvaged blood compared to allogeneic transfusion?
What happens to the concentration of free hemoglobin in patients after receiving salvaged blood compared to allogeneic transfusion?
What is a limitation imposed on the quantity of recovered blood that may be reinfused without processing?
What is a limitation imposed on the quantity of recovered blood that may be reinfused without processing?
What temperature range allows for up to 24 hours of storage for collected blood?
What temperature range allows for up to 24 hours of storage for collected blood?
salvaged blood compared with stored allogenic blood cells, which statement is true?
salvaged blood compared with stored allogenic blood cells, which statement is true?
What potential complication is associated with infusing large volumes of washed or unwashed blood?
What potential complication is associated with infusing large volumes of washed or unwashed blood?
What is the purpose of employing microaggregate filters during reinfusion?
What is the purpose of employing microaggregate filters during reinfusion?
What volume of collected blood is typically required to produce 225 to 250 mL of salvaged saline-suspended PRBCs?
What volume of collected blood is typically required to produce 225 to 250 mL of salvaged saline-suspended PRBCs?
What is the hematocrit (Hct) range of the salvaged PRBCs prepared for transfusion?
What is the hematocrit (Hct) range of the salvaged PRBCs prepared for transfusion?
What capacity of banked blood can some systems provide to a massively bleeding patient through continual blood processing?
What capacity of banked blood can some systems provide to a massively bleeding patient through continual blood processing?
when is contraindication for intraoperative blood collection ?
when is contraindication for intraoperative blood collection ?
What measure can mitigate clinical infection risks related to recovered blood cultures?
What measure can mitigate clinical infection risks related to recovered blood cultures?
What percentage reduction in the need for allogeneic blood transfusion was observed in adult elective surgeries using intraoperative cell salvage?
What percentage reduction in the need for allogeneic blood transfusion was observed in adult elective surgeries using intraoperative cell salvage?
In which type of surgeries was the greatest benefit of intraoperative blood salvage seen based on the text?
In which type of surgeries was the greatest benefit of intraoperative blood salvage seen based on the text?
What was the average amount of allogenic banked blood saved per patient through intraoperative blood salvage?
What was the average amount of allogenic banked blood saved per patient through intraoperative blood salvage?
Why do most programs set an upper limit on the volume of unprocessed blood that can be reinfused?
Why do most programs set an upper limit on the volume of unprocessed blood that can be reinfused?
What happens if transfusion of postoperative shed blood is not initiated within 6 hours of collection?
What happens if transfusion of postoperative shed blood is not initiated within 6 hours of collection?
