Podcast
Questions and Answers
Which type of membrane receptor is the fastest in response?
Which type of membrane receptor is the fastest in response?
- Tyrosine-kinase Linked with catalytic domain
- Ionotropic - Ligand-gated ion channels (correct)
- Protein kinase used as target proteins for neuronal signalling
- Metabotropic » 7TM spanning G-protein coupled
What type of G-protein is active when bound to GTP?
What type of G-protein is active when bound to GTP?
- Gγ subunit
- Gα subunit (correct)
- Gβ subunit
- G-protein complex
What is the main function of G-proteins in GPCRs?
What is the main function of G-proteins in GPCRs?
- Regulate second messenger production
- Carry information from receptor enzymes to effector enzymes (correct)
- Activate tyrosine-kinase linked receptors
- Directly bind to guanine nucleotides (GTP)
Which type of membrane receptor is the most common?
Which type of membrane receptor is the most common?
What is the primary product of Adenylyl cyclase activity?
What is the primary product of Adenylyl cyclase activity?
Which molecule activates nitric oxide synthase (nNOS)?
Which molecule activates nitric oxide synthase (nNOS)?
What is the primary product of Phospholipase E activity?
What is the primary product of Phospholipase E activity?
What is the primary function of nuclear receptor signaling?
What is the primary function of nuclear receptor signaling?
What is the primary function of nitric oxide as a secondary messenger?
What is the primary function of nitric oxide as a secondary messenger?
What is the primary function of cyclic GMP (cGMP) as a secondary messenger?
What is the primary function of cyclic GMP (cGMP) as a secondary messenger?
What is the primary function of diacylglycerol (DAG) as a secondary messenger?
What is the primary function of diacylglycerol (DAG) as a secondary messenger?
What is the primary function of cyclic AMP (cAMP) as a secondary messenger?
What is the primary function of cyclic AMP (cAMP) as a secondary messenger?
Which type of membrane receptor is the second fastest in response?
Which type of membrane receptor is the second fastest in response?
What is the primary function of the Gα subunit in G-protein coupled receptor (GPCR) signaling?
What is the primary function of the Gα subunit in G-protein coupled receptor (GPCR) signaling?
What is the main function of protein kinase in neuronal signaling?
What is the main function of protein kinase in neuronal signaling?
What is the primary role of G-proteins in GPCR signaling?
What is the primary role of G-proteins in GPCR signaling?
Which enzyme converts ATP to cyclic AMP and can be both stimulated and inhibited depending on the Gα subunit that binds to it?
Which enzyme converts ATP to cyclic AMP and can be both stimulated and inhibited depending on the Gα subunit that binds to it?
Which secondary messenger binds to protein kinase G and is produced from the conversion of GTP by guanylyl cyclase?
Which secondary messenger binds to protein kinase G and is produced from the conversion of GTP by guanylyl cyclase?
What activates protein kinase C and is produced from the conversion of PIP2 by an effector enzyme?
What activates protein kinase C and is produced from the conversion of PIP2 by an effector enzyme?
Which enzyme is activated by CA2+ and catalyzes the reaction between arginine and oxygen to produce nitric oxide?
Which enzyme is activated by CA2+ and catalyzes the reaction between arginine and oxygen to produce nitric oxide?
Which signaling pathway modulates pathways in cell surface signaling, involves membrane permeable hormones, and results in the regulation of gene expression?
Which signaling pathway modulates pathways in cell surface signaling, involves membrane permeable hormones, and results in the regulation of gene expression?
What forms a dimer when the signaling molecule binds to it and activates tyrosine kinase, leading to the phosphorylation of the receptor?
What forms a dimer when the signaling molecule binds to it and activates tyrosine kinase, leading to the phosphorylation of the receptor?
What activates RAS-activating protein, leading to the activation of the GTP/GBP exchange on the RAS protein?
What activates RAS-activating protein, leading to the activation of the GTP/GBP exchange on the RAS protein?
Which molecule binds to receptors in the nucleus, forms heterodimers, and binds to specific DNA sites, resulting in the regulation of gene expression?
Which molecule binds to receptors in the nucleus, forms heterodimers, and binds to specific DNA sites, resulting in the regulation of gene expression?
Which type of membrane receptor is the slowest in response?
Which type of membrane receptor is the slowest in response?
What is the primary function of G-proteins in GPCR signaling?
What is the primary function of G-proteins in GPCR signaling?
What is the main target of protein kinase in neuronal signaling?
What is the main target of protein kinase in neuronal signaling?
What is the primary role of the Gα subunit in GPCR signaling?
What is the primary role of the Gα subunit in GPCR signaling?
Which enzyme converts a membrane phospholipid (PIP2) into diacylglycerol (DAG) and inositol-1,4,5-triphosphate (IP₃)?
Which enzyme converts a membrane phospholipid (PIP2) into diacylglycerol (DAG) and inositol-1,4,5-triphosphate (IP₃)?
What is the primary product of Adenylyl cyclase activity?
What is the primary product of Adenylyl cyclase activity?
What activates protein kinase C and is produced from the conversion of PIP2 by an effector enzyme?
What activates protein kinase C and is produced from the conversion of PIP2 by an effector enzyme?
What is the main function of protein kinase G in cell signaling?
What is the main function of protein kinase G in cell signaling?
Which molecule is synthesised from vitamin and binds to receptors in the nucleus to modulate gene expression?
Which molecule is synthesised from vitamin and binds to receptors in the nucleus to modulate gene expression?
What is the primary role of GTP in G-protein coupled receptor (GPCR) signaling?
What is the primary role of GTP in G-protein coupled receptor (GPCR) signaling?
What is the primary function of cyclic GMP (cGMP) as a secondary messenger?
What is the primary function of cyclic GMP (cGMP) as a secondary messenger?
Which molecule is a gaseous secondary messenger that diffuses to neighbouring cells to activate guanylyl cyclase?
Which molecule is a gaseous secondary messenger that diffuses to neighbouring cells to activate guanylyl cyclase?
