Symptoms of Myasthenia Gravis

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Why is it important for the nurse to check swallowing before giving medications?

To prevent aspiration

What is a common sign that a patient with myasthenia gravis may experience in their vision?

Blurred vision

Why should smaller meals that are easy to chew be recommended for patients with myasthenia gravis?

To minimize effort in chewing

Why is it suggested to schedule meals during the peak time of medication for patients with myasthenia gravis?

To optimize chewing and swallowing muscle function

What is a potential consequence of not educating a patient with myasthenia gravis to take small bites and rest while eating?

Increased risk of choking

Why should large meals be preferred at the beginning of the day for patients with myasthenia gravis?

To align with progressive weakening throughout the day

Which symptom of Myasthenia Gravis involves the patient experiencing eyelid drooping in one or both eyes?

Double vision

What is a common sign of Myasthenia Gravis where the patient's face appears mask-like and lacks expression?

Experiencing fatigue and weakness

What diagnostic test for Myasthenia Gravis involves administering a medication called Edrophonium?

Tensilon test

Which complication of Myasthenia Gravis may require intubation and mechanical ventilation for the patient to breathe?

Myasthenic Crisis

What risk factor can lead to a severe acute exacerbation in Myasthenia Gravis patients known as Myasthenic Crisis?

Mental stress

Which symptom of Myasthenia Gravis involves the patient having a hoarse and very soft voice?

Slurred speech

Which of the following signs or symptoms is NOT commonly seen in myasthenia gravis?

Restlessness

What is a characteristic visual symptom experienced by individuals with myasthenia gravis?

Drooping eyelids

Which of the following treatments is a common intervention for myasthenia gravis?

Plasmapheresis

What type of medication is typically used to manage myasthenia gravis?

Anticholinesterase medications

When is the best time to assist a patient with myasthenia gravis in bathing and exercising?

After resting in the morning

Which of the following activities would be most challenging for a patient with myasthenia gravis?

Playing an outdoor sport in the afternoon

What is the primary function of the anticholinesterase medication Pyridostigmine in treating Myasthenia Gravis?

It improves muscle strength by preventing the breakdown of acetylcholine

When should a patient with Myasthenia Gravis take their anticholinesterase medication for optimal results?

30 to 60 minutes before a meal

Which of the following is NOT a common side effect of a cholinergic crisis?

Increased heart rate

What is the primary difference between a myasthenic crisis and a cholinergic crisis in a patient with Myasthenia Gravis?

They have different causes but similar symptoms

How should a cholinergic crisis be treated in a patient with Myasthenia Gravis?

No anticholinesterase medication and administer atropine

What are some factors that can worsen the symptoms of Myasthenia Gravis?

Menstrual cycle, sickness, stress, and extreme temperatures

Where is the thymus gland located in the human body?

Anteriorly in the upper part of the chest behind the sternum in between the lungs

What is the most appropriate time to administer Pyridostigmine to a patient with myasthenia gravis who is eating lunch at 1200?

1 hour before the patient eats (at 1100)

What is the primary function of Pyridostigmine in treating myasthenia gravis?

Preventing the breakdown of acetylcholine

Which type of receptors are damaged in a patient with myasthenia gravis?

Nicotinic acetylcholine receptors

What is the main reason for administering Pyridostigmine 1 hour before a patient with myasthenia gravis eats?

To ensure maximum muscle strength during chewing and swallowing

How does Pyridostigmine improve muscle strength in patients with myasthenia gravis?

By preventing the breakdown of acetylcholine

Study Notes

Monitoring Neuromuscular Status

  • Assess vision, voice, swallowing, facial appearance, strength in arms and legs, and cranial nerves to monitor neuromuscular status in patients with Myasthenia Gravis (MG)
  • Patients are at risk of injury and require assistance at all times
  • Speech pathologists will evaluate and recommend treatment based on findings

Safety Precautions

  • Patients may have double vision and require an eye patch to help
  • Arm and leg weakness is common
  • Patients are at risk of aspiration and require hob of greater than 30' while eating
  • Feeding tubes may be necessary, and nurses will manage them

Nutrition and Swallowing

  • Patients may have difficulty chewing and swallowing due to weakened muscles
  • Recommend small, easy-to-chew meals that require minimal effort
  • Schedule meals during peak medication time (30 minutes to 1 hour before eating)
  • Thicken liquids to aid swallowing
  • Take small bites and rest while eating
  • Large meals should be consumed early in the day when energy levels are highest

Signs and Symptoms of Myasthenia Gravis

  • Weakness in neck, face, arms, legs, and hands
  • Eyelid drooping (Ptosis) or double vision (Strabismus)
  • Mask-like appearance with no expression, looking sleepy
  • Difficulty swallowing due to weak muscles
  • No energy, with fatigue worsening throughout the day
  • Slurred speech, shortness of breath, and respiratory failure are possible complications

Complications of Myasthenia Gravis

  • Myasthenic Crisis: a severe acute exacerbation of MG, requiring intubation and mechanical ventilation
  • Risk factors include improper medication dosage, stress, and respiratory infection
  • Patients may experience severe weakness, respiratory failure, and require intubation

Diagnosis and Treatment

  • Edrophonium (Tensilon) test diagnoses MG by preventing acetylcholine breakdown, allowing more neurotransmitter at the neuromuscular junction
  • Anticholinesterase medications (e.g., Pyridostigmine) improve symptoms by preventing acetylcholine breakdown, increasing muscle strength
  • Thymectomy, corticosteroids, and plasmapheresis are treatment options, but not cholinesterase medications
  • Pyridostigmine should be taken 30-60 minutes before a meal to aid swallowing and chewing
  • Monitor for Myasthenic crisis (from not enough medication) or cholinergic crisis (from too much medication), both causing respiratory failure and severe muscle weakness

Learn about the symptoms of myasthenia gravis, a neuromuscular disease that causes weakness in various parts of the body such as the neck, face, arms, legs, and hands. Symptoms may include eyelid drooping (ptosis), mask-like appearance, difficulty swallowing, fatigue, double vision, slurred speech, and shortness of breath.

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