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Questions and Answers
What is the primary effect of sympathetic mass discharge?
Which of the following conditions could trigger sympathetic stimulation?
How do parasympathetic cardiovascular reflexes primarily function?
What is a consequence of parasympathetic mass stimulation?
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Which scenario would most likely cause prolonged GIT atony?
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What effect does the sympathetic nervous system have on muscle activity during stress?
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What initiates the bladder emptying reflex?
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Which of the following is NOT associated with sympathetic stimulation?
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What is the role of sympathetic tone at rest?
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What happens to the heart rate when parasympathetic activity is increased?
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What effect does cutting sympathetic nerves (sympathectomy) have on blood vessels?
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Which of the following statements about parasympathetic tone is correct?
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During which state does sympathetic tone maintain arterial blood pressure?
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What is a consequence of vagotomy in the heart?
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What influences gastrointestinal motility when sympathetic activity is heightened?
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How does cutting the parasympathetic nerve affect gastrointestinal activity?
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What effect does sympathetic mass stimulation have on the pupils during stress?
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How does sympathetic stimulation affect heart function?
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What physiological change occurs in the bronchioles during sympathetic activation?
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Which effect relates to the blood vessels during sympathetic mass stimulation?
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What is the effect of sympathetic stimulation on skeletal muscle contraction?
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What role does the spleen play during sympathetic mass stimulation?
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What effect does adrenaline have on blood glucose levels during stress?
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During sympathetic activation, what happens to sweat secretion?
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What is a defining characteristic of sympathetic stimulation in isolated portions of the system?
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Which reflex serves as an example of parasympathetic influence on gastrointestinal functions?
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In which scenario would a state of sympathetic mass discharge most likely occur?
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What is the primary consequence of parasympathetic mass stimulation?
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What is a result of sympathetic mass stimulation during stress responses?
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Which statement accurately describes the association between parasympathetic functions?
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How does the body react to the sympathetic response during emergency situations?
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What physiological change takes place in the sweat glands due to sympathetic stimulation during stress?
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What is the primary physiological role of sympathetic tone at rest?
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What happens to the heart rate when parasympathetic activity decreases?
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What is the initial effect of symapathectomy on blood vessels?
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What physiological change occurs in the gastrointestinal tract with increased parasympathetic activity?
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What effect does cutting parasympathetic nerves (vagotomy) have on heart rate?
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What long-term effect does cutting the sympathetic nerve have on arterial blood pressure?
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What physiological response is most associated with the constriction of blood vessels in the skin during sympathetic mass stimulation?
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Which process is increased in the liver during sympathetic mass stimulation to provide more energy?
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How does sympathetic activity affect the diameter of blood vessels?
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What is the primary effect of adrenaline secretion on metabolism during stress?
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What is a key factor involved in the regulation of sympathetic tone?
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During sympathetic activation, what happens to the strength of skeletal muscle contraction?
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What effect does sympathetic mass stimulation have on bronchioles to enhance respiratory function?
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How does the contraction of the splenic capsule during sympathetic activation affect blood volume?
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In the context of sympathetic stimulation, what is the role of exophthalmos?
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What is the overall effect of sympathetic mass stimulation on the cardiovascular system during stress?
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Study Notes
Sympathetic and Parasympathetic Tone at Rest
-
Sympathetic Tone
- Continuous discharge of impulses to organs, leading to mild activity
- Causes:
- Continuous basal discharge of sympathetic impulses
- Continuous basal secretion of adrenaline and noradrenaline from the adrenal medulla
- Sympathetic supply to blood vessels causes partial vasoconstriction, maintaining normal arterial blood pressure
-
Parasympathetic Tone
- Continuous discharge of impulses to organs, leading to mild activity
- Causes:
- Continuous basal discharge of parasympathetic impulses
- Continuous afferent impulses from baroreceptors in the carotid sinus and aortic arch along sinus and aortic nerves to the cardioinhibitory center in the medulla oblongata
- Effects:
- Decreases heart rate from 120 to 70 beats per minute
- Maintains normal gastrointestinal motility
Cutting Nerves
-
Sympathectomy (Cutting Sympathetic Nerves)
- Leads to immediate maximal vasodilatation
- After some time, intrinsic tone of smooth muscle in blood vessels increases, restoring vasoconstriction and returning normal arterial blood pressure
-
Vagotomy (Cutting Parasympathetic Nerves)
- Effects:
- Increases heart rate from 70 to 120 beats per minute
- Leads to prolonged gastrointestinal atony
- Effects:
Sympathetic and Parasympathetic Stimulation in Specific Organs
-
Sympathetic Stimulation
- Affects isolated portions of the body, like skin blood vessels during hot weather or hand sweating during writing
-
Parasympathetic Stimulation
- Cardiovascular Reflexes: Act only on the heart
- Gastrointestinal Reflexes: Act only on the gastrointestinal tract
Sympathetic Mass Discharge (Stress Response)
-
Causes:
- Emergency or stress conditions like hemorrhage, hypoglycemia, severe cold, pain, severe exercise, fear, fight, flight, and emotions
-
Effects:
- Enables the body to face stressful situations
- Increases the body's capacity for vigorous muscular activity
-
Specific Effects:
- Eyes: Pupillary dilatation, exophthalmos, widening of the palpebral fissure
- Heart: Increased heart rate, force of contraction, and blood pressure, supplying blood to vital organs and muscles
- Thorax: Bronchodilation for increased lung ventilation and oxygen supply
- Somatic: Vasoconstriction in the skin to limit bleeding, vasodilation of skeletal and cardiac muscle blood vessels, increased muscle contraction strength, delayed fatigue
- Spleen: Contraction of the splenic capsule, ejecting red blood cells into circulation, increasing blood volume and oxygen carrying capacity
- Adrenal Medulla: Secretion of adrenaline and noradrenaline potentiates sympathetic stimulation
- Liver: Increases glycogenolysis and glycolysis
- Other: Increased sweat secretion for heat loss
Parasympathetic Mass Stimulation
- Fatal
- Causes: Association between closely related parasympathetic functions, where one reflex can initiate another
-
Effects:
- Rectal Emptying Reflex: Initiates bladder emptying reflex, leading to simultaneous emptying of the bladder and rectum
- Salivary Secretion: Activates gastric secretion
- Gastric Secretion: Activates pancreatic secretions
Sympathetic Mass Stimulation Effects During Stress
- Increased Mental Activity and Cellular Metabolism
- Orbelli Phenomenon: Delay in the onset of muscle fatigue during stress
- Sympatho-Adrenal System: Adrenaline and noradrenaline secretion potentiates sympathetic stimulation
- Energy Supply: Increased blood glucose and free fatty acid levels
- Glycogenolysis & Glycolysis: Increased glycogenolysis in the liver and glycolysis in the muscle
- Heat Loss: Increased sweat secretion for heat loss
Sympathetic & Parasympathetic Tone
- At rest, both the sympathetic and parasympathetic nervous systems have a continuous basal discharge, known as tone.
-
Sympathetic tone:
- Leads to mild activity in organs due to continuous sympathetic nerve discharge.
-
Causes:
- Continuous basal secretion of adrenaline & noradrenaline from the adrenal medulla.
- Vasoconstriction in blood vessels, maintaining normal arterial blood pressure.
-
Parasympathetic tone:
- Leads to mild activity in organs due to continuous parasympathetic nerve discharge.
-
Causes:
- Continuous afferent impulses from baroreceptors in the carotid sinus and aortic arch, transmitted via the sinus & aortic nerves to the cardioinhibitory center in the medulla oblongata.
-
Effects:
- Heart: Decreases heart rate from 120 beats/min to 70 beats/min.
- Gastrointestinal tract (GIT): Maintains normal motility.
Cutting of Nerves
-
Sympathectomy (Cutting sympathetic nerves):
- Leads to immediate maximal vasodilatation.
- After some time, intrinsic tone of smooth muscles in blood vessels increases, restoring vasoconstriction and returning arterial blood pressure to normal.
-
Vagotomy (Cutting parasympathetic nerves):
- Heart: Increases heart rate from 70 to 120 beats/min.
- GIT: Leads to prolonged GIT atony (loss of muscle tone).
Localized Effects
-
Sympathetic stimulation can occur in isolated portions of the body.
-
Examples:
- Hot weather: Affects only skin blood vessels and sweat glands, without affecting other organs.
- Handwriting: Sweat secretion occurs only in the hand for a better grip.
-
Examples:
-
Parasympathetic stimulation often acts on specific organ systems.
-
Examples:
- Cardiovascular reflexes: Act only on the heart.
- GIT reflexes: Act only on the gastrointestinal tract.
-
Examples:
Mass Actions (Generalized Effects)
-
Sympathetic mass discharge (stress response):
- Occurs in emergency or stress conditions such as hemorrhage, hypoglycemia, severe cold, pain, severe exercise, fear, fight, flight, and emotions.
-
Effects:
- Pupillary dilatation (widening of pupils)
- Exophthalmos (bulging eyes)
- Increased heart rate
- Increased force of myocardial contraction
- Increased blood pressure
- Bronchodilation (widening of airways)
- Vasoconstriction in the skin
- Vasodilation in skeletal muscles and cardiac muscle
- Increased skeletal muscle strength
- Splenic contraction, releasing red blood cells into circulation
- Secretion of adrenaline and noradrenaline, potentiating sympathetic system stimulation (sympatho-adrenal system)
- Increased blood glucose and free fatty acid levels
- Increased glycogenolysis in the liver
- Increased glycolysis in muscles
- Increased mental activity
- Increased cellular metabolism
- Increased sweat secretion
-
Parasympathetic mass stimulation:
- Fatal
- Associated with closely related functions: One parasympathetic reflex can initiate another.
-
Examples:
- Rectal emptying reflex initiates bladder emptying reflex, leading to simultaneous emptying of both.
- Salivary stimulation activates gastric secretion, which then activates pancreatic secretions.
Sympathetic Mass Stimulation During Stress
- Eye: Pupillary dilatation, exophthalmos, and widening of the palpebral fissure (eyelid opening) for an increased field of vision.
- Heart: Increased heart rate, increased force of myocardial contraction, and elevated blood pressure, directing increased blood flow to vital organs and active muscles.
- Thorax: Bronchodilation for better lung ventilation and oxygen supply.
- Somatic System: Vasoconstriction in the skin to limit bleeding, vasodilation in skeletal and cardiac muscles, shifting blood flow to active areas. Increased skeletal muscle strength and delayed fatigue (Orbelli Phenomenon).
- Spleen: Contraction of the splenic capsule, releasing red blood cells into circulation to increase blood volume and oxygen-carrying capacity.
- Adrenal Medulla: Secretion of adrenaline and noradrenaline, potentiating the stimulation of the sympathetic system (sympatho-adrenal system).
- Liver: Increased glycogenolysis and glycolysis, providing energy for active muscles.
- Other: Increased sweat secretion for heat loss through evaporation, increased mental activity and cellular metabolism throughout the body.
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