T1 L14: Physiology of Neurons: Electrochemical properties and communication. (HJW)

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Questions and Answers

Which of the following is responsible for the resting membrane potential in neurons?

  • Inward Cl- current
  • Outward Ca2+ current
  • Inward Na+ current
  • Outward K+ current (correct)

Which of the following is responsible for depolarization during an action potential?

  • Inward Na+ current (correct)
  • Outward K+ current
  • Outward Ca2+ current
  • Inward Cl- current

Which of the following is responsible for the threshold voltage in an action potential?

  • Outward K+ current
  • Inward Cl- current
  • Inward Na+ current (correct)
  • Outward Ca2+ current

Which of the following is responsible for repolarization during an action potential?

<p>Outward K+ current (D)</p> Signup and view all the answers

According to the text, what is the conduction velocity for an alpha motor neuron?

<p>100 meters/second (D)</p> Signup and view all the answers

According to the text, what is the conduction velocity for C fibers responsible for pain?

<p>1 meter/second (A)</p> Signup and view all the answers

According to the text, what are the structural differences between alpha motor neurons and C fibers that contribute to the difference in their conduction velocity?

<p>Alpha motor neurons are myelinated, while C fibers are not. (D)</p> Signup and view all the answers

According to the text, why do neurons with a larger cross-sectional diameter conduct faster?

<p>Larger diameter leads to increased conduction velocity because of decreased intracellular resistance. (B)</p> Signup and view all the answers

Which of the following is true about the resting membrane potential (RMP) if extracellular Na+ concentration increases?

<p>The RMP becomes slightly less negative (D)</p> Signup and view all the answers

What happens to the RMP if extracellular K+ concentration suddenly increases?

<p>The RMP becomes less negative (C)</p> Signup and view all the answers

Which of the following is NOT a characteristic of action potentials?

<p>Variable in voltage (A)</p> Signup and view all the answers

Why do axons need action potentials instead of graded potentials to propagate signals long distances?

<p>Graded potentials diminish over distance (B)</p> Signup and view all the answers

Which of the following is true about selective serotonin reuptake inhibitors (SSRIs)?

<p>SSRIs block the reuptake of serotonin from the synaptic cleft. (D)</p> Signup and view all the answers

What would happen if the membrane suddenly became 100 times more permeable to Cl¯ ions than to any other ion?

<p>The membrane potential would become clamped to ECl (e.g. -65 mV). (A)</p> Signup and view all the answers

What is the effect of sodium channel inactivation on sodium channel activity during the after-hyperpolarization phase of the action potential?

<p>Initially reduces Na+ conduction, but over time recovery from inactivation occurs. (C)</p> Signup and view all the answers

How do neurons encode the intensity of a signal?

<p>Increased frequency of action potentials. (D)</p> Signup and view all the answers

Which ion's current is half blocked in the presence of this drug?

<p>K+ (D)</p> Signup and view all the answers

What happens to the resting membrane potential (RMP) when the K+ current is half blocked?

<p>It becomes more negative (C)</p> Signup and view all the answers

What effect does doubling the Na/K pump activity have on the RMP?

<p>It makes it more negative (C)</p> Signup and view all the answers

By how much does the membrane potential hyperpolarize due to the electrogenic effects of the Na/K pump?

<p>3 mV (D)</p> Signup and view all the answers

What effect does the drug have on the delayed rectifiers?

<p>It half blocks them (B)</p> Signup and view all the answers

What happens to the duration of the action potential when the delayed rectifiers are half blocked?

<p>It becomes longer (B)</p> Signup and view all the answers

Which of the following statements is true about the delayed rectifier K+ channels?

<p>If these channels open immediately upon depolarization, the depolarization would be slower and smaller. (A)</p> Signup and view all the answers

Which of the following can initiate a subthreshold stimulus in a neuron that might lead to an action potential?

<p>An electrical signal from a nearby part of the same neuron (C)</p> Signup and view all the answers

Why does the membrane potential (Vm) become more negative than the resting membrane potential (RMP) during the after-hyperpolarization (AHP)?

<p>An increased K+ current due to the delayed rectifier (C)</p> Signup and view all the answers

What would be the equilibrium potential for the nicotinic acetylcholine receptor (nAChR) if it is equally permeable to Na+ and K+?

<p>-17.5 mV (A)</p> Signup and view all the answers

Which of the following is responsible for the afterhyperpolarisation (AHP) phase of the action potential?

<p>Delayed rectifiers (C)</p> Signup and view all the answers

What is the main transmembrane force acting on an ion during an action potential?

<p>Electrochemical force (C)</p> Signup and view all the answers

What is the equilibrium potential for Na+ in a typical cell?

<p>~ +55 mV (A)</p> Signup and view all the answers

Why is the resting membrane potential -70 mV despite the presence of positive K+ ions inside the cell?

<p>K+ ions are balanced by negative ions inside the cell (B)</p> Signup and view all the answers

Which ion is responsible for the resting membrane potential of -70 mV in a typical cell?

<p>K+ (B)</p> Signup and view all the answers

What is the main transmembrane force acting on an ion at its equilibrium potential?

<p>Chemical force (B)</p> Signup and view all the answers

Which drug class blocks sodium channels as part of their mechanism of action?

<p>Local anesthetics (A)</p> Signup and view all the answers

What is the refractory period following an action potential?

<p>A period of decreased excitability (B)</p> Signup and view all the answers

What is the purpose of the nervous system?

<p>Communication (D)</p> Signup and view all the answers

What is the central nervous system responsible for?

<p>Information processing (B)</p> Signup and view all the answers

What is the peripheral nervous system responsible for?

<p>Motor activation (B)</p> Signup and view all the answers

Which part of the neuron is responsible for increasing conduction velocity?

<p>Myelin (A)</p> Signup and view all the answers

What is the main function of the pyramidal cell in the neocortex?

<p>Thinking (A)</p> Signup and view all the answers

Which type of neuron is responsible for coordination in the cerebellum?

<p>Perkin G cell (D)</p> Signup and view all the answers

What is the structure that contains the cell bodies of dorsal root ganglion cells?

<p>Dorsal root ganglion (D)</p> Signup and view all the answers

Which cells are able to divide throughout the lifespan and maintain neurons?

<p>Glia (B)</p> Signup and view all the answers

Which area of the brain is most rostral in the cerebral cortex?

<p>Rostral (D)</p> Signup and view all the answers

Which Broadman area corresponds to the sensory cortex?

<p>Area 3 (D)</p> Signup and view all the answers

What is the main difference between neurons and glia?

<p>Neurons form myelin sheaths (D)</p> Signup and view all the answers

Which part of the neuron is primarily responsible for sensing and transmitting information?

<p>Cell body (D)</p> Signup and view all the answers

What is the purpose of the myelin sheath in neurons?

<p>To insulate the axon electrically (D)</p> Signup and view all the answers

What are the nodes of Ranvier in relation to the myelin sheath?

<p>Gaps in the myelin sheath (A)</p> Signup and view all the answers

What is the function of the axon terminals in a neuron?

<p>To transmit electrical signals to other neurons (B)</p> Signup and view all the answers

Which type of neuron is among the least numerous in the nervous system?

<p>Bipolar neurons (C)</p> Signup and view all the answers

What is the main characteristic of pseudo unipolar cells?

<p>They have two poles but look like they have one (C)</p> Signup and view all the answers

What is the key feature of chemical synapses?

<p>They have a large gap between the presynaptic and postsynaptic neuron (D)</p> Signup and view all the answers

What happens in divergent signaling?

<p>A single neuron sends signals to multiple neurons (D)</p> Signup and view all the answers

Which cells are more abundant in the nervous system compared to neurons?

<p>Astrocytes (A)</p> Signup and view all the answers

What is the function of glial cells?

<p>Support and protect neurons (C)</p> Signup and view all the answers

What is another name for glial cells?

<p>Neural glia (B)</p> Signup and view all the answers

What can be observed in the background of the image shown in the text?

<p>Purple cells (B)</p> Signup and view all the answers

What do glial cells do in relation to blood vessels?

<p>Regulate blood flow (C)</p> Signup and view all the answers

Which cells are shown as big cells in the image?

<p>Neurons (B)</p> Signup and view all the answers

What is the main function of glial cells in the nervous system?

<p>Support and protection (A)</p> Signup and view all the answers

Which part of the nervous system is derived from the ectoderm?

<p>Central nervous system (C)</p> Signup and view all the answers

What is the function of a ganglion in the nervous system?

<p>Group of cell bodies outside the central nervous system (C)</p> Signup and view all the answers

Which type of neurons occur only in the central nervous system?

<p>Interneurons (B)</p> Signup and view all the answers

What is the main difference between glia and neurons?

<p>Glia have no action potentials, while neurons do (C)</p> Signup and view all the answers

Which cells are able to divide throughout the lifespan and maintain neurons?

<p>Glia (B)</p> Signup and view all the answers

Which part of the neuron is responsible for receiving inputs?

<p>Dendrites (B)</p> Signup and view all the answers

What is the function of the myelin sheath in neurons?

<p>To insulate the axon and increase conduction velocity (A)</p> Signup and view all the answers

What is the main difference between dorsal and ventral in the brain?

<p>Dorsal is the upper part of the brain, while ventral is the lower part (A)</p> Signup and view all the answers

What is the main function of Broadman areas in the cerebral cortex?

<p>To name and characterize different regions of the cerebral cortex (A)</p> Signup and view all the answers

Which type of neuron is among the least numerous in the nervous system?

<p>Bipolar neurons (B)</p> Signup and view all the answers

What is the key feature of chemical synapses?

<p>One-way transmission (A)</p> Signup and view all the answers

What is the main function of convergent connections in the nervous system?

<p>To integrate multiple inputs into a single neuron (A)</p> Signup and view all the answers

What is the size of the synaptic cleft in a chemical synapse?

<p>30 nanometers (D)</p> Signup and view all the answers

Which part of the neuron is responsible for increasing conduction velocity?

<p>Myelin sheath (B)</p> Signup and view all the answers

What is the main difference between neurons and glia?

<p>Neurons are responsible for transmitting signals, while glia provide support and insulation (C)</p> Signup and view all the answers

What is the purpose of the myelin sheath in neurons?

<p>To increase conduction velocity (D)</p> Signup and view all the answers

What is the main transmembrane force acting on an ion during an action potential?

<p>Electrical gradient (C)</p> Signup and view all the answers

What is the main function of glial cells in the nervous system?

<p>To support and protect neurons (D)</p> Signup and view all the answers

What is the difference between glial cells and neurons?

<p>Glial cells are more abundant than neurons (D)</p> Signup and view all the answers

What are glial cells sometimes called?

<p>Neural glia (D)</p> Signup and view all the answers

Which type of cells are supporting cells in the nervous system?

<p>Glial cells (D)</p> Signup and view all the answers

What is the main difference between glial cells and neurons in terms of numbers?

<p>There are more total glial cells than neurons (B)</p> Signup and view all the answers

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