Swine Influenza Overview

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12 Questions

What are the classical clinical swine influenza associated with?

Influenza A virus subtypes H1N1, H1N2, and H3N2

Which species are important hosts for influenza A viruses?

Humans, primates, pigs, horses, sea mammals, and birds

What is the difference in stability between avian and mammalian influenza viruses?

Avian viruses are more stable than mammalian viruses

How do unstable gene constellations in avian species become stable?

In secondary hosts

What plays a part in influenza virus species specificity?

Specific gene combinations

What are the methods by which influenza viruses cross the species barrier?

Polygenic and not well understood

What naming convention is used for new variants in pig husbandry?

A/species/localization/isolate number/year of isolation

What do the HA and NA proteins on the viral envelope stand for?

Hemagglutinin and Neuraminidase

What is the role of the H protein in the virus infection process?

The H protein binds to sialic acid and mediates virus infection of the host.

Why is the pig considered a 'mixing vessel' in terms of virus transmission?

The pig can be infected by both avian and mammalian viruses due to possessing both types of receptors.

What are the two types of changes that the surface HA and NA antigens undergo?

Antigenic drift and antigenic shift

How many proteins are encoded by the 8 RNA segments of the virus?

10 or 11 proteins

Test your knowledge on swine influenza, an important cause of broncho-interstitial pneumonia in pig-keeping areas worldwide. Learn about the changing viruses, genetic drift, and the classical clinical types associated with the disease.

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