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Questions and Answers
Which of the following is true about the growth of solid tumors?
Which of the following is true about the growth of solid tumors?
- Solid tumors can only grow up to 5 mm in diameter without angiogenesis.
- Solid tumors can grow to any size without angiogenesis.
- Solid tumors can only grow up to 10 mm in diameter without angiogenesis.
- Solid tumors can only grow up to 1-2 mm in diameter without angiogenesis. (correct)
Which of the following is a role of neovascularization in tumor growth?
Which of the following is a role of neovascularization in tumor growth?
- Neovascularization supplies waste products to tumors.
- Neovascularization inhibits tumor growth.
- Neovascularization provides needed nutrients and oxygen to tumors. (correct)
- Neovascularization prevents the formation of endothelial cells.
Which of the following growth factors are secreted by newly formed endothelial cells during neovascularization?
Which of the following growth factors are secreted by newly formed endothelial cells during neovascularization?
- Vascular Endothelial Growth Factor (VEGF) and Transforming Growth Factor (TGF) (correct)
- Insulin-Like Growth Factors (IGF) and Platelet-Derived Growth Factors (PDGF)
- Epidermal Growth Factor (EGF) and Fibroblast Growth Factor (FGF)
- Tumor Necrosis Factor (TNF) and Interleukin-6 (IL-6)
Why do solid tumors require angiogenesis for growth?
Why do solid tumors require angiogenesis for growth?
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What is the maximal distance across which oxygen, nutrients, and waste can diffuse from existing blood vessels?
What is the maximal distance across which oxygen, nutrients, and waste can diffuse from existing blood vessels?
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