Sustained Release Medications Overview

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Questions and Answers

What is the main difference between sustained release and prolonged action medications?

  • Sustained release medications are available in various forms while prolonged action medications are strictly tablets.
  • Sustained release medications provide a rapid initial dosage followed by maintenance doses, while prolonged action provides a steady rate of drug replenishment. (correct)
  • Sustained release medications deliver one dose while prolonged action medications require multiple doses.
  • Sustained release medications maintain drug levels for longer while prolonged action medications deliver faster initial doses.

What characteristics define sustained action medications?

  • They create higher drug levels than what is eliminated from the body.
  • They provide only a single rapid dose without follow-up doses.
  • They deliver an initial dose for a prompt therapeutic response, followed by doses to sustain effect. (correct)
  • They replenish eliminated drug at a rate equal to the elimination rate.

Which term best describes medications that release drugs over extended periods?

  • Rapid action
  • Intermittent release
  • Sustained release (correct)
  • Immediate action

Why do all currently available branded products focus on prolonged action dosage forms?

<p>They match the therapeutic effects while simplifying dosage regimens. (C)</p> Signup and view all the answers

What factor is crucial for maintaining a sustained level of drug in the body?

<p>The rate of drug release must equal the rate of drug elimination. (B)</p> Signup and view all the answers

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Study Notes

Medications with Prolonged and Sustained Action

  • Significant advancements have been made in developing medications that provide precise dosage over extended periods.
  • Various products promote therapeutic effects that last longer than standard single doses, categorized under terms like prolonged action, sustained release, continuous action, and timed release.

Definition of Sustained Action Products

  • Sustained action or sustained release medications deliver an initial dose for an immediate therapeutic effect.
  • After the initial dose, additional doses maintain therapeutic levels beyond the duration of a typical single dose.
  • To maintain effective therapeutic levels, the drug release rate must align with the drug elimination rate.

Characteristics of Prolonged Action Products

  • Prolonged action medications provide an initial rapid response while replenishing the drug at a rate different from the elimination rate.
  • Current branded medications are primarily designed in prolonged action dosage forms, despite objectives aiming for sustained action.

Benefits of Sustained and Prolonged Action Dosage Forms

  • Offer convenience of fewer doses while ensuring prolonged therapeutic effects.
  • Improved patient compliance due to reduced frequency of medication intake.

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