Surrogacy Evaluation Process

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Questions and Answers

What is the primary purpose of conducting a psychological evaluation for intended parents in the surrogacy process?

To gauge family dynamics and relationships

To assess financial stability for surrogacy

To evaluate mental and emotional readiness for surrogacy (correct)

To check physical health conditions

Which procedure is essential to assess the reproductive health of intended parents prior to surrogacy?

DNA sequencing

Nutritional assessment

Medical screening including sperm tests and ovarian reserve checks (correct)

Psychological counseling

Why is infectious disease testing necessary for intended parents?

To ensure compliance with tax regulations

To protect the health of the surrogate and the child (correct)

To assess lifestyle choices of intended parents

To determine the need for nutrition counseling

What do the medical screening tests for intended parents specifically check?

Reproductive system health and genetic factors Signup and view all the answers

What potential issues can arise from not conducting the required tests for intended parents?

Increased chances of infectious disease transmission Signup and view all the answers

Which of the following is NOT a purpose of the required tests for intended parents?

To determine lifestyle choices Signup and view all the answers

What is assessed during the medical screening of male intended parents?

Sperm quality and quantity Signup and view all the answers

Which of the following infectious diseases is specifically tested for in intended parents?

Cytomegalovirus IgG and IgM Signup and view all the answers

What is the primary purpose of Carrier Genetic Testing (CGT) when planning a family?

To assess the risk of having a child with a genetic disease Signup and view all the answers

What is the expected outcome if both parents are carriers of the same genetic mutation?

There is a 25% chance of having a sick child Signup and view all the answers

During which process does DNA fragmentation in sperm primarily occur?

Spermatogenesis and storage Signup and view all the answers

What does a normal Karyotype indicate for a male individual?

46XY Signup and view all the answers

Why is it recommended to use the Igenomix genetic lab for Carrier Genetic Testing?

Comprehensive comparative analysis with egg donors is easier Signup and view all the answers

What is the time frame for receiving the CGT report after the sample is collected?

35-45 days Signup and view all the answers

Which condition is NOT a disorder typically analyzed by Carrier Genetic Testing?

Down Syndrome Signup and view all the answers

What should Intended Parents (IPs) do if they wish to decline genetic testing?

Inform the coordinator by email Signup and view all the answers

What is a possible consequence of a high percentage of sperm showing DNA fragmentation?

Higher risk of embryo implantation failure Signup and view all the answers

What is the initial step required for Intended Parents to undergo Carrier Genetic Testing?

Organize a WhatsApp group with an Igenomix representative Signup and view all the answers

What is the primary purpose of Carrier Genetic Testing (CGT)?

To identify potential genetic disorders in children Signup and view all the answers

Which factor is NOT part of the initial required tests for intended parents in the surrogacy process?

Comprehensive metabolic panel Signup and view all the answers

What does a normal sperm DNA fragmentation rate indicate?

Healthy DNA structure within sperm Signup and view all the answers

Which test measures the ability of sperm to swim effectively?

Sperm motility Signup and view all the answers

What is required in the semen analysis before collection?

Three days of abstinence Signup and view all the answers

Why is karyotyping performed during the surrogacy process?

To assess chromosome abnormalities Signup and view all the answers

Which of the following infections is NOT screened in the initial tests for intended parents?

Influenza Signup and view all the answers

What does the term 'sperm morphology' refer to?

The shape and structure of sperm Signup and view all the answers

Which carrier genetic testing panel is highly recommended over the others?

CGT Plus Signup and view all the answers

What is the recommended normal pH range for semen?

7.2 to 8.0 Signup and view all the answers

What is the significance of performing background checks on intended parents?

To ensure legal compliance and suitability Signup and view all the answers

What role does the presence of white blood cells in a semen sample indicate?

Potential infection or inflammation Signup and view all the answers

During which day of the female partner's menstrual cycle is vaginal ultrasound typically performed for fertility assessment?

Day 2-3 Signup and view all the answers

What is the primary purpose of infection screening for intended parents?

To prevent the transmission of STIs to the child Signup and view all the answers

Study Notes

Psychological Evaluation

Evaluates mental and emotional readiness of intended parents for the surrogacy process.
Identifies psychological challenges potentially impacting the surrogacy journey.
Ensures parents are equipped to handle emotional complexities.

Medical Screening

Involves sperm tests for males and ovarian reserve check-ups for females.
Assesses reproductive health to guide the surrogacy process effectively.
Identifies health issues that may affect the surrogate or child's well-being.

Infectious Disease Testing

Screens for Hepatitis B, Hepatitis C, HIV, Syphilis, Chlamydia, Gonorrhea, and other infections.
Aims to prevent communicable disease transmission during surrogacy.
Protects the health of the surrogate and child while ensuring legal compliance.

Genetic Testing

Includes Carrier Genetic Testing (CGT) and karyotype analysis.
Evaluates genetic compatibility and risks for intended parents.
Aims to prevent genetic disorders and supports informed decision-making.

Legal and Background Checks

Confirms legal status and eligibility of intended parents for surrogacy.
Protects rights and interests of all participants in the surrogacy arrangement.
Ensures compliance with legal regulations governing surrogacy.

Sperm Lab Analysis

Evaluates sperm concentration, motility, morphology, and DNA fragmentation.
Helps identify potential fertility problems based on structured sperm analysis.
Normal sperm parameters include pH 7.2-8.0, volume 1.5-7.6 ml, and motility 40-81%.

DNA Fragmentation

Refers to changes or breaks in sperm DNA, impacting fertility and embryo development.
High DNA fragmentation correlates with poor implantation and increased miscarriage rates.

Karyotype Analysis

Provides a visual representation of an individual’s chromosomes.
Identifies chromosomal abnormalities and genetic disorders.
Normal karyotypes for males and females are noted as 46XY and 46XX, respectively.

Carrier Genetic Testing (CGT)

Determines risk of genetic diseases in offspring by identifying recessive gene carriers.
Utilizes Next-Generation Sequencing (NGS) for a comprehensive panel analysis.
Essential for ensuring compatibility between intended parents and egg donors.

Recommended CGT Panels

Essential (24 genes), Plus (579 genes), and Exome (2200 genes) with varying prices.
Plus or Exome programs highly recommended for thorough lifetime genetic reports.

Testing Process and Responsibilities

Organize sample collection with an Igenomix representative and send a saliva kit.
Return sample to the lab, with results typically available in 35-45 days.
Results influence additional testing for selected egg donors if required.

Documentation and Communication

Coordinators manage collection and storage of all required tests and documents.
Clear communication channels must be established, including WhatsApp for assistance and documentation sharing.
Patients have the right to decline tests, but must document their decision formally.

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Description

This quiz covers the essential steps involved in the surrogacy evaluation process, including psychological evaluation, medical screening, infectious disease testing, and genetic testing. It aims to provide an understanding of the comprehensive assessments intended parents undergo to ensure a healthy surrogacy journey.