Questions and Answers
What is the primary purpose of the psychological evaluation for intended parents?
Which of the following tests is included in medical screening for intended parents?
What is the importance of infectious disease testing in the context of surrogacy?
What might poor sperm quality indicate during medical screening?
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Why is it important to assess the ovarian reserve of female partners in the medical screening process?
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What is the consequence of not conducting a psychological evaluation for intended parents?
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Which of the following diseases is NOT part of the infectious disease testing for intended parents?
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How does medical screening directly impact the surrogacy process?
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What is one of the main issues associated with a high percentage of sperm showing DNA fragmentation?
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What does a normal Karyotype indicate in males?
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What is the probability of having a child with a genetic disease if both parents are carriers of the same mutation?
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Which genetic conditions can be analyzed using Next-Generation Sequencing (NGS) in Carrier Genetic Testing?
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What action is required from intended parents (IPs) before conducting Carrier Genetic Testing?
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What happens after the sample for Carrier Genetic Testing is received at the laboratory?
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If an intended parent refuses Carrier Genetic Testing after counseling, what must they do?
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What additional screening is needed if a genetic carrier mutation is found in the intended father?
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What is one benefit of using the Igenomix genetic lab for Carrier Genetic Testing?
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If the chosen egg donor is found to be a carrier of the same genetic mutation, who bears the cost of testing a second donor?
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What is the main purpose of Carrier Genetic Testing (CGT) in the context of surrogacy?
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Which of the following tests is highly recommended but not mandatory for intended parents?
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What does a semen analysis NOT evaluate?
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Why is it important to conduct legal and background checks for intended parents in surrogacy?
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Which panel of CGT tests is the most comprehensive and assesses the highest number of genes?
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What minimum sperm concentration is considered normal in a semen analysis?
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What is the significance of sperm DNA fragmentation in infertility assessments?
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Which of the following infections is NOT included in the screening for intended parents?
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What does karyotype analysis assess in intended parents?
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Which hormone is NOT typically monitored in female fertility tests?
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What is the recommended abstinence period before a sperm collection for analysis?
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Why are infection screenings conducted for intended parents?
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What is the normal range for sperm motility according to semen analysis parameters?
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What is one significant role of conducting initially required tests in surrogacy?
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Study Notes
Psychological Evaluation
- Evaluates mental and emotional readiness of intended parents for the surrogacy process.
- Identifies psychological challenges potentially impacting the surrogacy journey.
- Ensures parents are equipped to handle emotional complexities.
Medical Screening
- Involves sperm tests for males and ovarian reserve check-ups for females.
- Assesses reproductive health to guide the surrogacy process effectively.
- Identifies health issues that may affect the surrogate or child's well-being.
Infectious Disease Testing
- Screens for Hepatitis B, Hepatitis C, HIV, Syphilis, Chlamydia, Gonorrhea, and other infections.
- Aims to prevent communicable disease transmission during surrogacy.
- Protects the health of the surrogate and child while ensuring legal compliance.
Genetic Testing
- Includes Carrier Genetic Testing (CGT) and karyotype analysis.
- Evaluates genetic compatibility and risks for intended parents.
- Aims to prevent genetic disorders and supports informed decision-making.
Legal and Background Checks
- Confirms legal status and eligibility of intended parents for surrogacy.
- Protects rights and interests of all participants in the surrogacy arrangement.
- Ensures compliance with legal regulations governing surrogacy.
Sperm Lab Analysis
- Evaluates sperm concentration, motility, morphology, and DNA fragmentation.
- Helps identify potential fertility problems based on structured sperm analysis.
- Normal sperm parameters include pH 7.2-8.0, volume 1.5-7.6 ml, and motility 40-81%.
DNA Fragmentation
- Refers to changes or breaks in sperm DNA, impacting fertility and embryo development.
- High DNA fragmentation correlates with poor implantation and increased miscarriage rates.
Karyotype Analysis
- Provides a visual representation of an individual’s chromosomes.
- Identifies chromosomal abnormalities and genetic disorders.
- Normal karyotypes for males and females are noted as 46XY and 46XX, respectively.
Carrier Genetic Testing (CGT)
- Determines risk of genetic diseases in offspring by identifying recessive gene carriers.
- Utilizes Next-Generation Sequencing (NGS) for a comprehensive panel analysis.
- Essential for ensuring compatibility between intended parents and egg donors.
Recommended CGT Panels
- Essential (24 genes), Plus (579 genes), and Exome (2200 genes) with varying prices.
- Plus or Exome programs highly recommended for thorough lifetime genetic reports.
Testing Process and Responsibilities
- Organize sample collection with an Igenomix representative and send a saliva kit.
- Return sample to the lab, with results typically available in 35-45 days.
- Results influence additional testing for selected egg donors if required.
Documentation and Communication
- Coordinators manage collection and storage of all required tests and documents.
- Clear communication channels must be established, including WhatsApp for assistance and documentation sharing.
- Patients have the right to decline tests, but must document their decision formally.
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Description
Explore the essential initial tests required for intended parents in the surrogacy process. This quiz emphasizes the importance of psychological evaluations and how they help assess the readiness of parents to handle the emotional challenges of surrogacy.
