88 Questions
Where are Nosocomial Infections acquired?
Hospitals, nursing homes, or other health care facilities
What factor poses a significant risk of nosocomial infections?
Interaction between three factors
What type of bacteria is commonly associated with surgical infections?
Gram-positive aerobic cocci like Staphylococci
Where do community-acquired infections occur?
Outside of healthcare facilities
How can infection be transmitted through skin abrasions?
Direct contact with contaminated bodily fluids
What is a potential source of prion transmission mentioned in the text?
Contaminated neurosurgical equipment
How can potentially infected patients be identified?
By serology
What is recommended for the disposal of disposable items related to patient care?
Careful disposal
How can hepatitis B transmission risk be assessed?
Assessing risk factors like IV drug use
What is recommended for non-disposable equipment used in patient care?
Specific treatment and sterilization
Which bodily fluid is mentioned as a potential source of infection?
Saliva
How can infection be transmitted through contact with contaminated equipment?
Transfer of prions by neurosurgical equipment
Which antibiotic is mostly resistant to E.pidermidis?
Penicillin
What is the principal anaerobic Gram-negative bacillus that colonizes the large bowel, vagina, and oropharynx?
Bacteroides fragilis
Which antibiotic is effective against gram-negative aerobic/facultative/anaerobic bacilli?
Aminoglycosides
What type of infections are major SSI associated with?
Surgical site infections
What type of infections are included in hospital acquired infections (HAI)?
Urinary tract infections
Which bacteria cause gas gangrene?
Clostridium perfringens
Which bacteria acts in synergy with aerobic Gram-negative bacilli to cause surgical site infections and abdominal abscesses?
Bacteroides fragilis
What antibiotic is given to allergic patients who are sensitive to penicillin?
Erythromycin
Which bacteria are major causes of urinary tract and surgical site infections?
E.coli
What type of infections are minor SSI associated with?
Surgical site infections
What are the types of Surgical Site Infection (SSI) mentioned in the text?
Superficial wound infection, Deep wound infection, Organ space infection
Which of the following is not a natural host defense against Surgical Site Infection (SSI)?
High blood sugar levels
What are the sources of infection mentioned in the text?
Primary (endogenous) and Secondary (exogenous) sources
What are the principles of treatment for Surgical Site Infection (SSI) mentioned in the text?
Prescribing antibiotics, Removing sutures, Draining abscesses
What are some risk factors for wound infection mentioned in the text?
Age, Malnutrition, Immunosuppression
Which signs and symptoms are associated with wound infection according to the text?
Heat (warm skin), Red skin surrounding the wound, Pain associated with fever and chills
What are some modes of occupational infections among health workers mentioned in the text?
Direct percutaneous inoculation of infected blood (needle-stick injuries, scalpel wounds)
Which type of defense includes neutrophils and macrophages?
Cellular defense
What is one principle of achieving healing for Surgical Site Infection (SSI)?
Achieving healing by secondary or delayed primary intention
Which type of Surgical Site Infection (SSI) affects musculofascial layers?
Deep wound infection
What are some signs and symptoms associated with wound infection according to the text?
Swelling, Discharge or pus from the wound, Odor coming from the wound
Where are Nosocomial Infections acquired?
Hospitals, nursing homes, or other health care facilities
What is a common bacteria causing surgical infection?
Staphylococci (S.aureus)
What factors pose a significant risk of nosocomial infections?
Interaction between three factors
What are Nosocomial Infections also known as?
Hospital acquired infections
How can infection be transmitted by fomites?
Through contaminated equipment
What is a recommended procedure to minimize transmission of infection?
Identify infected patients by serology
How can potentially infected patients be identified?
By risk factors such as IV drug use
What is an example of an infectious bodily fluid mentioned in the text?
Blood
What is recommended for the disposal of disposable items related to patient care?
Careful disposal of disposable items
What is the principal anaerobic Gram-negative bacillus that colonizes the large bowel, vagina, and oropharynx?
Bacteroides fragilis
Which antibiotic is effective against gram-negative aerobic/facultative/anaerobic bacilli?
Ciprofloxacin
What are some signs and symptoms associated with wound infection according to the text?
Localized pain and redness at the wound site
What are the types of Surgical Site Infection (SSI) mentioned in the text?
Superficial wound infection, Deep wound infection, Organ space infection
What are the natural host defenses against Surgical Site Infection (SSI)?
Mechanical barriers, Chemical defenses, Cellular defenses
What are some risk factors for wound infection mentioned in the text?
Age, Malnutrition, Type of surgery
What is a potential source of occupational infections among health workers mentioned in the text?
Direct percutaneous inoculation of infected blood
Which type of defense includes antibodies?
Humoral defenses
What is a principle of treatment for Surgical Site Infection (SSI) mentioned in the text?
Prescribing antibiotics
What are some sources of infection mentioned in the text?
Primary (endogenous) sources present in the host and secondary (exogenous) sources acquired from outside the body.
Which antibiotic is mostly resistant to E.pidermidis?
Penicillin
What is the principal anaerobic Gram-negative bacillus that colonizes the large bowel, vagina, and oropharynx?
Bacteroides fragilis
What type of infections are minor SSI associated with?
Surgical site infections
Which bacteria cause gas gangrene?
Clostridium perfringens
What type of defense includes neutrophils and macrophages?
Innate immunity
What type of bacteria are major causes of urinary tract and surgical site infections, especially E.coli?
Gram-negative aerobic/facultative/anaerobic bacilli
What is the term used for infections acquired in hospitals, nursing homes, or other health care facilities?
Nosocomial infections
What is a common bacterium causing surgical infection mentioned in the text?
Staphylococcus aureus
Which interaction poses a significant risk of nosocomial infections according to the text?
Interaction between three factors including patients' immune system, medical devices, and hygiene practices
In which country do nosocomial diseases cause thousands of deaths annually according to the text?
United States
How can infection be transmitted by fomites?
Via contaminated equipment such as neurosurgical tools
What is a recommended procedure to minimize transmission of infection?
Regular handwashing with soap and water
How are infected (infectious) patients identified?
By serology testing
What is recommended for non-disposable equipment used in patient care?
Thorough cleaning and sterilization
What are some risk factors for wound infection mentioned in the text?
Presence of foreign bodies in the wound
What are some sources of infection mentioned in the text?
Contaminated medical equipment
What is a potential source of prion transmission mentioned in the text?
Contaminated surgical instruments
How can potentially infected patients be identified?
By identifying risk factors such as IV drug use for hepatitis B carriage
Which antibiotic is indicated for allergic patients who are sensitive to penicillin, according to the text?
Erythromycin
Which bacteria is a major cause of urinary tract infections (UTI) and surgical site infections (SSI) after bowel operations?
Escherichia coli
What type of infection is associated with systemic signs of inflammation such as tachycardia, pyrexia, and leukocytosis?
Major Surgical Site Infection (SSI)
Which bacterium causes gas gangrene?
Clostridium perfringens
What are hospital-acquired infections (HAI) defined as?
Infections acquired in the hospital environment or from medical staff during admission
What type of bacteria colonize the large bowel, vagina, and oropharynx and act in synergy with aerobic Gram-negative bacilli to cause surgical site infections and abdominal abscesses after colorectal or gynaecological surgery?
Escherichia coli
What type of defense includes antibodies?
Humoral defenses
Which type of Surgical Site Infection (SSI) affects musculofascial layers?
Deep SSI
What are some risk factors for wound infection mentioned in the text?
Obesity, diabetes, and liver diseases
Which interaction poses a significant risk of nosocomial infections according to the text?
Direct contact with infected patients
What is a potential source of occupational infections among health workers mentioned in the text?
Direct percutaneous inoculation such as needle-stick injuries
What type of bacteria are major causes of urinary tract and surgical site infections, especially E.coli?
Aerobic bacteria
How are infected (infectious) patients identified?
By visible signs and symptoms
What is recommended for non-disposable equipment used in patient care?
Thorough cleaning and sterilization
What antibiotic is given to allergic patients who are sensitive to penicillin?
Clindamycin
What is one principle of achieving healing for Surgical Site Infection (SSI)?
Draining abscesses
What type of defense includes neutrophils and macrophages?
Cellular defenses
Where do community-acquired infections occur?
Outside healthcare settings
Study Notes
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Surgical Site Infection (SSI) is the invasion of organisms into surgical wounds after the breakdown of host defenses.
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Types of SSI: 1. Superficial wound infection (skin), 2. Deep wound infection (musculofascial layers), 3. Organ space infection (abdominal and pelvic abscesses).
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Natural host defenses include mechanical barriers (skin, mucous membranes), chemical (low gastric pH), cellular (neutrophils, macrophages, lymphocytes), and humoral (antibodies) defenses.
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Sources of infection include primary (endogenous) sources present in the host and secondary (exogenous) sources acquired from outside the body.
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Principles of treatment include prescribing antibiotics, removing sutures, draining abscesses, and achieving healing by secondary or delayed primary intention.
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Risk factors for wound infection include general (age, malnutrition, immunosuppression, endocrine and metabolic disorders, hypoxia, and anaemia) and local (type of surgery, length of procedures, necrotic tissue, residual local malignancy, foreign bodies, and ischemia) factors, as well as microbiological factors.
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Signs and symptoms of wound infection include spreading heat (warm skin), red skin surrounding the wound, pain associated with fever and chills, swelling, discharge or pus, and odor coming from the wound, along with generalized weakness, anorexia, and loss of function or movement.
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Modes of occupational infections among health workers include direct percutaneous inoculation of infected blood, such as needle-stick injuries and scalpel wounds.
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E.pidermidis: form clumps, mostly resistant to penicillin but sensitive to cloxacillin and vancomycin.
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b-Streptococci (S.pyogen, S.faecalis): form chains, sensitive to penicillin, but allergic patients are given erythromycin or cephalosporines.
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Gram-positive anaerobic bacilli: include Clostridium perfringens, tetani, and difficile, cause gas gangrene, tetanus, and colitis respectively.
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Gram-negative aerobic/facultative/anaerobic bacilli: include E.coli, Klebsiella, Pseudomonas, and Proteus; major causes of urinary tract and surgical site infections, especially E.coli.
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Aminoglycosides and ciprofloxacin are effective against gram-negative aerobic/facultative/anaerobic bacilli.
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Bacteroides fragilis: principal anaerobic Gram-negative bacillus, colonizes the large bowel, vagina, and oropharynx; acts in synergy with aerobic Gram-negative bacilli to cause surgical site infections and abdominal abscesses.
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Hospital acquired infections (HAI): infections acquired in the hospital environment or from medical staff during admission; types include respiratory infections, urinary tract infections, bacteraemia, and surgical site infections.
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Major SSI: occurs when a wound discharges a large quantity of pus and the patient shows systemic signs of inflammation.
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Minor SSI: occurs when a wound discharges little pus and is not associated with systemic signs of inflammation.
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Surgical Site Infection (SSI) is the invasion of organisms to tissues after the host's defenses have been compromised.
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Types of SSI: superficial (skin), deep (musculofascial layers), and organ space (abdominal and pelvic abscesses).
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Natural host defenses include mechanical barriers (skin and mucous membranes), chemical (low gastric pH), cellular (neutrophils, macrophages, and lymphocytes), and humoral (antibodies).
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Sources of infection: primary (endogenous, from the host) and secondary (exogenous, from outside the body).
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Principles of treatment: use of antibiotics, removal of sutures when necessary, and draining abscesses.
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Risk factors for wound infection can be general (age, malnutrition, immunosuppression, obesity, underweight, diabetes, liver diseases, renal failure, and hypoxia) or local (type of surgery, length of procedures, presence of necrotic tissue, residual local malignancy, and ischemia).
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Microbiology factors, such as lack of antibiotic prophylaxis and virulence of organisms, also play a role in wound infections.
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Signs and symptoms of wound infection include spreading heat (warm skin), redness around the wound, pain, swelling, discharge, odor, and generalized weakness.
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Healthcare workers are at risk for occupational infections through direct percutaneous inoculation, such as needle-stick injuries and scalpel wounds.
Test your knowledge about the types of surgical site infection, including superficial wound infection, deep wound infection, and organ space infection. Learn about the invasion of organisms to tissues after breakdown of host defenses.
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