6 Questions
What is the result of high surface tension in the alveolar lining?
Prevention of alveolar collapse
What properties of DPPC contribute to its orientation in the air-liquid interface inside the alveolus?
Hydrophilic and hydrophobic properties
Which of the following is a function of surfactant?
To promote lung expansion
Which equipment is NOT necessary for surfactant therapy?
Sterile scissors
What is an alternative to the surfactant kit?
Size 5Fr feeding tube
What is the purpose of the tape measure in surfactant therapy?
To measure the patient's height
Study Notes
Surface Tension and Surfactant
- High surface tension in the alveolar lining can lead to alveolar collapse, making it difficult for the lungs to expand and exchange oxygen and carbon dioxide.
Properties of DPPC
- DPPC (Dipalmitoylphosphatidylcholine) has a hydrophobic tail and a hydrophilic head, which contributes to its orientation in the air-liquid interface inside the alveolus, reducing surface tension.
Functions of Surfactant
- Surfactant is a complex mixture of lipids and proteins that reduces the surface tension in the alveoli, allowing the lungs to expand and facilitating gas exchange.
- Surfactant also helps to prevent alveolar collapse and improves lung compliance.
Surfactant Therapy
- Surfactant therapy is not necessary for the use of a ventilator.
- An alternative to the surfactant kit is a vial of surfactant.
- The tape measure is used in surfactant therapy to measure the baby's weight, which is necessary to determine the correct dose of surfactant.
Test your knowledge on the mechanism of action and functions of surfactant in the lungs. Learn about the molecular forces and properties that contribute to the decrease in surface tension, and how surfactant promotes lung expansion.
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