Questions and Answers
What is the brand name of Beractant?
What is the purpose of Calfactant?
For premature infants less than 29 weeks of gestational age at high risk of RDS.
What is Poractant used for?
For premature infants with RDS to reduce mortality and pneumothoraces.
Luinactant is a synthetic peptide containing surfactant replacement therapy.
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What does surfactant do?
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Surfactant complications can include _______.
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What should we expect with surfactant administration?
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Study Notes
Surfactant Drugs Overview
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Beractant (Survanta)
- Class: Surfactant
- Used for premature infants <1250g or with surfactant deficiency
- Administered prophylactically within 15 minutes of birth, or as rescue within 8 hours
- Given through endotracheal tube after warming to body temperature
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Calfactant (Infasurf)
- Class: Surfactant
- Indicated for infants <29 weeks gestation at high risk for Respiratory Distress Syndrome (RDS)
- Administered prophylactically within 30 minutes post-birth or as rescue within 72 hours
- Administered via catheter
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Poractant (Curosurf)
- Class: Surfactant
- Provides rescue treatment for premature infants with RDS, reducing mortality and pneumothoraces
- Can also address respiratory failure from Group V streptococcal infection in neonates
- Administered at room temperature via endotracheal tube
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Luinactant (Surfaxin)
- Class: Surfactant
- A synthetic peptide used as surfactant replacement therapy
- Designed for prevention of RDS in at-risk infants
- Administered via syringe
Function of Surfactants
- Replaces and replenishes deficient endogenous surfactant in neonatal RDS
- Surfactants can be recycled in type 2 cells to maintain a pool, regulating surface tension in the lungs
Expected Outcomes with Surfactant Administration
- Increases oxygen levels in the bloodstream
- Improves lung compliance for better respiratory function
Complications Associated with Surfactants
- Risk of airway occlusion; bubbling should be avoided
- High arterial oxygen factors may lead to complications
- Risk of Retinopathy of Prematurity (ROP) due to excessive oxygen
- Possible overventilation causing lower carbon dioxide levels
- Pulmonary injury may occur
- Surfactants are ineffective in treating Adult Respiratory Distress Syndrome (ARDS)
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Description
This quiz features flashcards focused on various surfactant drugs, specifically designed for use in premature infants. Learn the brand names, classes, modes of action, and administration details of surfactants like Beractant and Calfactant. Perfect for medical students or healthcare professionals prepping for exams.
