Chapter 38/39 Pharm

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What should patients taking Beta-Lactam antibiotics avoid consuming?

Dairy, grapefruit juice, and alcohol

What is a common adverse effect associated with Tetracyclines in children, infants, and fetuses?

Tooth discoloration

Which antibiotic is commonly given before surgery to clean out the gastrointestinal tract?

Neomycin

What is the most common Aminoglycoside antibiotic?

Gentamicin

Which antibiotic is used to treat MRSA and Clostridioides Difficile (C-Diff)?

Vancomycin

What labs are checked to monitor kidney function in patients taking antibiotics?

Creatinine level

Which adverse effect is associated with Sulfonamides in the blood?

Hemolytic anemia

What is a common adverse effect of Sulfonamides in the integumentary system?

Steven-Johnson Syndrome

Which group includes Beta-Lactam antibiotics?

Penicillin, cephalosporins, carbapenems, monobactams

Why should patients with a history of throat swelling or hives from penicillin avoid cephalosporins?

Penicillin and cephalosporin have similar chemical structures.

Why do patients taking Beta-Lactam antibiotics need to use an alternative form of birth control?

Because Beta-Lactam antibiotics interfere with oral contraceptives

What is the rationale behind advising patients taking Beta-Lactam antibiotics to avoid Warfarin, NSAIDs, and Antacids?

To prevent drug-drug interactions that may affect treatment outcomes

What is a potential adverse effect of Aminoglycoside antibiotics?

Nephrotoxicity/Ototoxicity

Which Macrolide antibiotic is used to treat Clostridioides Difficile (C-Diff)?

Fidaxomicin/Dificid

What is a black box warning associated with Quinolone antibiotics?

Tendonitis

When should Tetracyclines not be given?

To pregnant or breastfeeding women, or children under age 8

What is a noted adverse effect of Erythromycin/E-Mycin based on the text?

Ototoxicity

What is a possible complication leading to risk of Beta-Lactam antibiotic allergic reactions, as indicated in the text?

Generic and Brand name confusion

Which antibiotic class mentioned in the text is associated with adverse effects of Clostridioides Difficile (C-Diff) infection?

Tetracyclines

What is the purpose of running peak and trough labs for patients taking antibiotics?

To prevent toxicity by monitoring drug levels

Which antibiotic is primarily used to treat gynecological infections and Clostridioides Difficile (C-Diff)?

Metronidazole/Flagyl

Why should Quinolones never be given with oral anticoagulants?

To avoid potential drug interactions leading to bleeding risks

How many generations do Cephalosporins have?

5

Which antibiotic is commonly used to treat non-complicated urinary tract infections?

Nitrofurantoin

What is a potential adverse effect of Vancomycin?

Red-Man Syndrome

When asking patients about known drug allergies, what specific information is important to inquire about?

The type of reaction they had

Which antibiotic class is typically associated with big gun infections such as sepsis?

Carbapenems

What is a common adverse effect associated with Sulfonamides in the body?

Convulsions

Which blood test is typically used to check liver function?

AST/ALT

When should patients be advised to drink plenty of water while taking antibiotics?

To prevent kidney damage

What medication is used to treat complicated UTIs?

Ciprofloxacin

What is usually the first symptom of an allergic reaction to antibiotics mentioned in the text?

Redness or rash to the face and trunk

In what situations are Macrolide antibiotics indicated according to the information provided?

Strep, respiratory infections, syphilis, and STDs

Which antibiotic is specifically mentioned for the treatment of osteomyelitis in the text?

Clindamycin

infection following a previous infection especially when caused by microorganisms that are resistant to or have become resistant to the antibiotics used earlier.

superinfection

An example of superinfection is

Clostridioides Difficile (C-Diff).

The labs BUN/GFR check your ______ .

kidneys

Match

urticaria = Hives angioedema = facial swelling pruritus = itchy skin Hepato = Liver

____ are often combined with another antibiotic.

Sulfonamides

Carbapenems end in ______

Penem

Macrolides end in ______ and spell FACE.

CIN

Macrolides end in CIN and spell ______

face

Tetracyclines end in ______

cycline

Quinolones end in _____

floxacin

Aminoglycosides end in CIN and spell ______

TANG

Aminoglycosides end in ______ and spell TANG.

CIN

Antibiotic therapy tailored to treat organism identified with cultures.

Definitive therapy

Treatment of an infection before specific culture information has been reported or obtained.

Empiric Therapy

Treatment with antibiotics to prevent an infection (as in intraabdominal surgery or after trauma)

Prophylactic Therapy

Test your knowledge on superinfection following antibiotic treatment, with a focus on the example of Clostridioides Difficile (C-Diff) and the adverse effects of Sulfonamides in the blood and integumentary system.

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