Sugar Derivatives

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Questions and Answers

What happens to a carbon atom in some sugar derivatives?

  • It forms an ether linkage with another sugar
  • It forms an ester linkage with a fatty acid
  • It is oxidized to a carboxyl group (correct)
  • It is reduced to an aldehyde group

What is the result of the formation of an ester linkage between the C-1 carboxylate group and the C-5 hydroxyl group of a sugar?

  • A disaccharide is formed
  • A lactone is formed (correct)
  • A glycoprotein is formed
  • A nucleotide sugar is formed

What is the function of N-acetylglucosamine and N-acetylmuramic acid in biology?

  • They are components of mammalian glycoproteins
  • They are components of the bacterial cell wall (correct)
  • They are involved in the metabolism of fatty acids
  • They are involved in the synthesis of ATP

What type of bond is formed when a hydroxyl group in a sugar is replaced with an -NH2 group?

<p>Amino sugar formation (B)</p> Signup and view all the answers

What type of charge does an acidic sugar have at neutral pH?

<p>Negative charge (D)</p> Signup and view all the answers

What is the result of replacing a hydroxyl group with an -NH2 group in a hexose?

<p>Formation of an amino sugar (C)</p> Signup and view all the answers

What is the common modification of hexoses in metabolic pathways?

<p>Phosphorylation on hydroxyl groups (B)</p> Signup and view all the answers

Which of the following is a characteristic of acidic sugars?

<p>Presence of a carboxylate group (C)</p> Signup and view all the answers

What is the function of N-acetylneuraminic acid and fucose in biology?

<p>Components of oligosaccharide chains of mammalian glycoproteins (C)</p> Signup and view all the answers

What is the result of substituting -H for -OH in a sugar?

<p>Formation of a deoxy sugar (C)</p> Signup and view all the answers

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Study Notes

Sugar Derivatives

  • Hydroxyl groups in parent compounds can be replaced with other substituents or oxidized to form carboxyl groups
  • Hexoses in metabolic pathways are commonly phosphorylated on hydroxyl groups

Amino Sugars

  • One -OH group in the parent hexose is replaced with a -NH2 group
  • Examples: N-acetylglucosamine and N-acetylmuramic acid, which are components of the bacterial cell wall

Deoxy Sugars

  • Produced by substituting -H for -OH in the parent hexose

Acidic Sugars

  • Contain a carboxylate group, which confers a negative charge at neutral pH
  • Examples: N-acetylneuraminic acid (sialic acid) and fucose, components of the oligosaccharide chains of mammalian glycoproteins

Lactones

  • Formed through an ester linkage between the C-1 carboxylate group and the C-5 hydroxyl group of the sugar

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