Substance Use Disorders and Treatment
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Questions and Answers

What is the estimated heritability percentage for alcohol dependence?

50-60%

How did Cloninger's Stockholm Adoption Study contribute to understanding alcohol dependence?

It identified traditional early-onset and nontraditional late-onset drinking patterns, highlighting the genetic and environmental influences on alcohol use.

What distinguishes Type 1 and Type 2 alcoholics according to Cloninger's Typology?

Type 2 alcoholics have early and heavy drinking patterns, while Type 1 alcoholics have long periods without drinking followed by uncontrollable impulses to drink.

Which personality traits are associated with Type 2 alcoholics?

<p>Antisocial traits and higher risk attributed to family history of alcoholism.</p> Signup and view all the answers

What impact does family environment have on the drinking behavior of Type 2 alcoholics?

<p>The family environment has no measurable effect; boys began drinking regardless of whether their families drank.</p> Signup and view all the answers

What is the relationship between chronic marijuana abuse and psychosis?

<p>Chronic marijuana abuse increases the risk of psychosis due to the effects of THC and dopamine transmission.</p> Signup and view all the answers

How does tobacco use relate to the onset of schizophrenia?

<p>Tobacco use is associated with a doubled risk of developing schizophrenia, with increased smoking correlating with greater risk.</p> Signup and view all the answers

What is the significance of the BT+CMPT approach in autism treatment?

<p>BT+CMPT should be considered a frontline treatment and includes parent operant conditioning training.</p> Signup and view all the answers

Describe the typical age of onset for schizophrenia and its implications.

<p>The typical onset of schizophrenia occurs in late adolescence to early adulthood, with early onset linked to a worse clinical course.</p> Signup and view all the answers

How did the diagnostic criteria for autism change from DSM-3 to DSM-4?

<p>DSM-3 required 6 mandatory criteria, while DSM-4 introduced 16 optional criteria with 8 required for diagnosis.</p> Signup and view all the answers

What are the implications of the statement 'There is no autism epidemic'?

<p>It suggests that the increase in autism diagnoses is not due to a true rise in cases but rather a change in diagnostic criteria and awareness.</p> Signup and view all the answers

What is the estrogen hypothesis regarding schizophrenia in women?

<p>The estrogen hypothesis suggests that higher estrogen levels have a protective effect against psychotic symptoms in women.</p> Signup and view all the answers

How does socioeconomic status (SES) affect schizophrenia?

<p>Low SES can exacerbate the impacts of schizophrenia by affecting education and overall outcomes.</p> Signup and view all the answers

What are some examples of persistent deficits in social communication according to DSM-5?

<p>Examples include abnormal social approach, failure of back-and-forth conversations, and lack of interest in sharing emotions.</p> Signup and view all the answers

Why are Black Americans diagnosed with schizophrenia at higher rates compared to other ethnic groups?

<p>Black Americans are diagnosed with schizophrenia twice as often as white or Latino Americans due to biases among clinicians.</p> Signup and view all the answers

Why is the term 'facilitated communication' considered controversial in the context of autism?

<p>It is viewed as bogus since it incorrectly assumes that physical limitations in individuals with autism are the only barriers to communication.</p> Signup and view all the answers

What criteria must be met for a diagnosis of Restricted, Repetitive Patterns of Behavior in autism?

<p>A diagnosis requires the presence of at least 2 out of 4 specified deficits.</p> Signup and view all the answers

What impact does early substance use have on schizophrenia?

<p>Early substance use can lead to an earlier onset of schizophrenia and contribute to a more severe progression of the disorder.</p> Signup and view all the answers

What are some social consequences of schizophrenia?

<p>Schizophrenia can lead to impaired relationships, issues with self-care, and may result in reliance on family or homelessness.</p> Signup and view all the answers

What does the term 'early developmental symptoms' imply in the context of autism diagnosis?

<p>It implies that symptoms must be identified during early developmental periods, although the timing is not clearly defined.</p> Signup and view all the answers

How has the language in the DSM criteria impacted autism diagnosis?

<p>The broadened language has lowered the threshold for diagnosis, making it easier to identify autism.</p> Signup and view all the answers

What compensatory effect does the brain produce in response to excess chemical release during substance use?

<p>The brain produces a compensatory response to counteract the effects of excessive chemical release, helping to prevent potentially lethal consequences.</p> Signup and view all the answers

In classical conditioning with morphine, what is the Unconditioned Stimulus (UCS) and what is its corresponding Unconditioned Response (UCR)?

<p>The UCS is morphine, and the UCR is pain reduction.</p> Signup and view all the answers

What role does conditioned stimulus (CS) play in the context of morphine use and pain sensitivity?

<p>The CS, such as injection paraphernalia, can lead to a conditioned response (CR) that increases pain sensitivity.</p> Signup and view all the answers

Explain why overdoses are more likely to occur in novel environments.

<p>Overdoses are more likely in novel environments because the body does not trigger the expected compensatory response, leading to greater risk when the same dose is used.</p> Signup and view all the answers

Describe the pathway that characterizes substance use leading to substance use disorder (SUD).

<p>The pathway includes exposure, use, escalation, and ultimately consequences leading to substance use disorder.</p> Signup and view all the answers

Identify two types of influences that contribute to substance use disorder.

<p>Social and cultural influences, as well as psychological and biological factors, contribute to substance use disorder.</p> Signup and view all the answers

What critical behavior must be explained regarding substance use disorder and individual drug use?

<p>The critical behavior to explain is the escalation of drug use, as most individuals do not start using in large quantities.</p> Signup and view all the answers

How does cultural context affect attitudes towards alcohol consumption in different countries?

<p>Cultural context heavily influences attitudes and practices surrounding alcohol, such as celebratory drinking in the USA compared to more restrained practices in France.</p> Signup and view all the answers

What are positive symptoms of schizophrenia?

<p>Positive symptoms include cognitive, perceptual, and behavioral abnormalities such as delusions, hallucinations, and bizarre behaviors.</p> Signup and view all the answers

How do positive symptoms differ from negative symptoms in schizophrenia?

<p>Positive symptoms are excesses or distortions of normal functions, while negative symptoms represent a deficit in such functions.</p> Signup and view all the answers

What is a common characteristic of delusions in schizophrenia?

<p>Delusions are unshakable false beliefs that remain despite evidence to the contrary.</p> Signup and view all the answers

What percentage of schizophrenia patients typically experience auditory hallucinations?

<p>Approximately 50% of patients experience auditory hallucinations.</p> Signup and view all the answers

Name one type of negative symptom in schizophrenia.

<p>Avolition is one type of negative symptom characterized by a lack of motivation.</p> Signup and view all the answers

Describe what is meant by 'bizarre behavior' in the context of positive symptoms.

<p>Bizarre behavior refers to actions that are inconsistent with reality, such as taking off clothes in public or wandering aimlessly.</p> Signup and view all the answers

How has the DSM-III contributed to diagnosing schizophrenia symptoms?

<p>The DSM-III emphasized positive symptoms and largely ignored negative symptoms in its diagnostic criteria.</p> Signup and view all the answers

What is the most common type of hallucination experienced by schizophrenia patients?

<p>Auditory hallucinations are the most common type experienced by patients.</p> Signup and view all the answers

What effect do medications typically have on positive symptoms of schizophrenia?

<p>Medications are often effective in treating positive symptoms, leading to remission.</p> Signup and view all the answers

What characterizes catatonic behavior in schizophrenia?

<p>Catatonic behavior is marked by rigidity, immobility, unresponsiveness, and sometimes mutism.</p> Signup and view all the answers

What is the primary purpose of antagonist treatment in addiction recovery?

<p>To block the euphoric effects of substances like heroin, thereby reducing cravings.</p> Signup and view all the answers

Why is it crucial for individuals using Naltrexone to be highly motivated?

<p>Motivation is essential for the treatment to be effective, as it requires commitment to recovery.</p> Signup and view all the answers

How does Acamprosate function in managing withdrawal symptoms?

<p>It reduces withdrawal symptoms and dulls the high from alcohol intoxication.</p> Signup and view all the answers

What is a core principle of Alcoholics Anonymous (AA)?

<p>Admitting powerlessness over alcohol is considered a fundamental principle.</p> Signup and view all the answers

What role does social support play in the Alcoholics Anonymous approach?

<p>It fosters a sense of normalization and helps participants feel they are not alone in their struggles.</p> Signup and view all the answers

What is the goal of the harm reduction movement in addressing drug use?

<p>To modify drug use behaviors to reduce risks to public health and safety.</p> Signup and view all the answers

Describe one advantage of the controlled use approach.

<p>It allows for lifestyle changes without requiring complete abstinence, which can enhance compliance.</p> Signup and view all the answers

What does the harm reduction movement contrast with in terms of addiction policy?

<p>It contrasts with the punitive approaches that prioritize incarceration over treatment.</p> Signup and view all the answers

In what way does AA's lack of enforced confidentiality affect its members?

<p>It may lead to concerns about anonymity, which can deter some individuals from participating.</p> Signup and view all the answers

What criticism exists regarding the sex bias in Alcoholics Anonymous?

<p>Critics question the use of male-centered language and the exclusion of women's perspectives.</p> Signup and view all the answers

Study Notes

General Treatment Issues

  • Recognizing America's Drug Problem
    • Common issue: Denial
    • Failure to recognize a problem until it destroys their lives
    • Especially common for substance use disorders (SUDs)
    • Leads to reluctance in seeking help (unless mandated).
  • Withdrawal Challenges
    • Symptoms, detoxification, cravings—high-risk periods of 18 months
    • Intense cravings and withdrawal symptoms
    • Overpowering cravings and access to the substance makes relapse highly likely
    • High rate of relapse during the withdrawal period.
  • Seeking Treatment
    • Importance of personal motivation
    • Old thinking: needing to hit rock bottom
    • New thinking: help can be provided earlier to help prevent this issue.

Psychopharmacological Treatment

  • Marked as anti-craving drugs, but not a magical pill
  • Combined with therapy
  • Aversive Treatment (e.g., Disulfiram [Antabuse])
    • Prevents breakdown of acetaldehyde: causes unpleasant effects when drinking
    • Dizziness, sweating, rapid heartbeat.
  • Agonist Substitution (e.g., Methadone)
    • Mimics opioid effects to reduce cravings; slower, less intense high.
    • Has sedative effects to curb cravings for heroin, but it's addictive.
  • Antagonist Treatment (e.g., Naltrexone)
    • Blocks the effects of the drug (like heroin or alcohol)
    • Prevents euphoria from these drugs
    • Theoretically reduces cravings.

Community-Based Approach

  • Alcoholics Anonymous (AA)
    • Core principle: disease model, powerlessness, spirituality.
    • First step: admitting powerlessness over the substance/alcohol
    • Sex bias: disproportionate number of male members
    • Social support: crucial component based on anonymity.
    • Normalization: emphasizes togetherness to combat this mental health issue
  • Harm Reduction Movement
    • Goal: reduce public health risk and potential harm from substance use
    • Examples: needle exchange, methadone maintenance, and safe use campaigns.

Controlled Drinking (CD)

  • Techniques (e.g., Problem-solving training, moderation skills)
  • Monitoring internal cues, simulated drinking practice
  • Training in these skills: can help address severe abuse in a limited manner
  • Positive findings using controlled drinking (in labs) but inconsistent long-term results.
  • Results in some cases show that controlled drinking is a potentially useful treatment but not in all cases.

Relapse Prevention & Cognitive Behavioral Therapy (CBT)

  • Underlying dysfunctional psychological mechanism
  • Faulty/maladaptive learning + thinking
  • Positive expectancies + Abstinence Violation Effect:
    • Distorted thinking patterns e.g. "I can't drink like I used to"
    • Identifying distortions
    • Strategies to change maladaptive patterns
  • High-Risk Situations & Coping Strategies
  • Develop problem-solving techniques and coping skills.

Alternative Community-Based Approaches

  • Examples: Rational Recovery (RR), Self-Management & Recovery Training (SMART), Moderation Management (MM), Moderatedrinking.com (MD)
  • Resource: SAMHSA's National Helpline

The Challenge of Clinical Work with Children

  • Key issues
    • Complexity of cases
    • Age-out of problems
    • Larger number of disorders (other than personality disorders) experienced
  • Assessment issues
    • Limitations of self-reports, developmental level (vocabulary / complexity).
    • Importance of multi-mode assessments (multiple reporters, multiple tools).
    • Critical diagnostic process

DSM Limitations for Children

  • Lacks sensitivity to childhood differences
  • OCD, SAD, PTSD - differs in manifestation & expression between adults and children
  • No change in duration, feeling of detachment as a symptom for children in the DSM (different from adults)
    • Symptom presentations (e.g. PTSD) are different in children than in adults
  • No formal criteria, nor subtypes (e.g. PDD) for childhood mood disorders
    • Criteria for disorders have been modified to better capture and understand their presentations, including considering family history and other traits specific to childhood.

Pediatric Bipolar Disorder (PBD)

  • Diagnosis: Same as adults.
  • Prevalence: Rare, increased office visits, hospitalizations under 12.
  • 40% increase in office visits (1990s compared to now)
  • 50% of children experiencing it for over 2 years; a high rate of diagnosis.

Disruptive Mood Dysregulation Disorder (DMDD)

  • Criteria: "Severe" recurrent temper outbursts, grossly out of proportion to the situation.

Childhood Major Depression

  • Prevalence: Less than 5% in general to 35% at 19 years
  • Disorder course
    • Average major depressive episodes lasts ~8 months
    • 90% recover in 2 years
    • 70% within 5 years.
  • High comorbidity: 30-95%
    • Mood disorders (e.g., bipolar disorder).
    • Anxiety disorders.
    • Conduct disorder.
  • Etiology
    • Temperament has a crucial role in this disorder
    • Negative emotionality is related to depression/anxiety and low positive emotionality
    • Early parental loss is associated with later onset depression, especially in young children

General Child Treatment Issues

  • Contextual factors
    • Children's functioning within contexts.

Childhood Depression Treatment

  • Dealing with skill deficits.
  • Promising approaches, including CBT, IPT (interpersonal therapy), family therapy, SSRIs.
  • Challenges with pharmacotherapy
    • Biological differences; need for appropriate child-specific dosing.
    • Side effects, developmental impact.
  • Treatment needs to focus on parents, teachers, and daycare providers.

Antidepressant Controversy

  • Paxil vs placebo
    • Increase in suicidality rates with Paxil (3.4%) compared to placebo (1.2%)
  • FDA Black Box Warnings _ Change in prescription rate post-warning.
  • Current Recommendations _Prozac is the only SSRI approved for use in children/adolescents.

The Antidepressant Controversy

  • Continued interest in efficacy and safety of antidepressants in children.
  • Ongoing research efforts to better understand and treat childhood disorders.

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Description

Explore key issues surrounding substance use disorders, including denial and withdrawal challenges. The quiz also covers the importance of seeking treatment and examines psychopharmacological options. Gain insights into the complexities of treatment and recovery.

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