Structure of Small Blood Vessels
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Questions and Answers

What characterizes discontinuous or sinusoidal capillaries?

  • Uninterrupted vascular endothelium and continuous basal lamina
  • Closed structure with tight junctions between endothelial cells
  • Numerous openings in the capillary wall with a continuous basal lamina
  • Larger diameter with large openings and intercellular gaps (correct)

How do postcapillary venules differ from regular venules?

  • Postcapillary venules contain a thicker tunica media.
  • Postcapillary venules do not participate in the exchange of materials.
  • Postcapillary venules are smaller and have a higher permeability. (correct)
  • Postcapillary venules have fewer intercellular gaps.

What role do vasodilator substances like serotonin and histamine play in small venules?

  • They help decrease blood flow through the venules.
  • They make venules less permeable to maintain tight junctions.
  • They promote the formation of new venules from capillaries.
  • They increase intercellular distances, making the venules 'leaky'. (correct)

What is the function of arteriovenous shunts in specialized tissues?

<p>To facilitate direct blood flow between arterioles and venules. (B)</p> Signup and view all the answers

What is true about the cellular structure of postcapillary venules?

<p>They possess pericytes instead of a tunica media. (D)</p> Signup and view all the answers

What is the primary function of arterioles in relation to capillary networks?

<p>They control blood flow by smooth muscle contraction. (A)</p> Signup and view all the answers

Which of the following describes the structure of capillaries?

<p>They have walls made of a single layer of endothelial cells. (A)</p> Signup and view all the answers

What role do pericytes play in relation to capillaries?

<p>They represent a population of stem cells. (B)</p> Signup and view all the answers

What are metarterioles and what is their significance?

<p>They act as precapillary sphincters to regulate blood flow. (B)</p> Signup and view all the answers

In the normal relationship between arterioles and capillaries, what happens when the smooth muscle in an arteriole contracts?

<p>Blood flow into the capillaries is reduced or shut off. (D)</p> Signup and view all the answers

What is contained within the tunica media of arterioles?

<p>One or two layers of smooth muscle. (D)</p> Signup and view all the answers

Which characteristics apply to both arterioles and capillaries?

<p>They play crucial roles in regulating blood flow. (A)</p> Signup and view all the answers

What is the function of the tunica adventitia in arterioles?

<p>To provide structural support and elasticity. (A)</p> Signup and view all the answers

Flashcards

Arteriole Structure

Arterioles have three layers: intima (endothelium), media (smooth muscle), and adventitia (connective tissue).

Arteriole Function

Arterioles control blood flow to capillaries by adjusting smooth muscle contraction, thus regulating blood flow.

Metarteriole

Smaller branches of arterioles. Smooth muscle cells act as precapillary sphincters.

Capillary Structure

Extremely small blood vessels (thin walled) composed of a single layer of endothelial cells and their basal lamina.

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Capillary Function

Capillaries facilitate fluid exchange, allowing gases, nutrients, and waste products to move into and out of the blood.

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Capillary Size

Capillaries have a diameter smaller than red blood cells, sometimes requiring them to fold for passage.

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Pericytes

Undifferentiated mesenchymal stem cells associated with capillaries, supporting the endothelial cells.

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Arteriovenou Shunt

Distal portion of the metarteriole, merging with the postcapillary venule, lacking smooth muscle.

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Capillary Types

There are three types of capillaries: continuous, fenestrated, and discontinuous (sinusoidal). Each type has unique structural features that determine its function.

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Continuous Capillary

A continuous capillary has a continuous layer of endothelial cells and a continuous basal lamina. This structure allows tight regulation of substance passage.

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Fenestrated Capillary

Fenestrated capillaries have small, pore-like openings in their endothelial cell walls, allowing for faster exchange of fluids and small molecules.

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Discontinuous Capillary

Discontinuous capillaries have large gaps between endothelial cells and a discontinuous basal lamina, permitting the passage of large molecules and cells.

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Postcapillary Venule Function

Postcapillary venules are responsible for the exchange of materials between blood and tissues, and for leukocyte migration.

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Study Notes

Structure of Small Vessels

  • Small blood vessels, including arterioles, capillaries, and postcapillary venules, are crucial for blood flow and exchange of material.
  • Arterioles have three layers (tunicae): intima (inner layer with endothelium only), media (smooth muscle, one or two layers), and adventitia (outer layer of loose connective tissue)
  • Arterioles control blood flow to capillaries through contraction of smooth muscle.
  • Metarterioles are smaller branches of arterioles, with smooth muscle cells acting as precapillary sphincters regulating blood flow.
  • A thoroughfare channel is the distal part of the metarteriole, lacking smooth muscle and connecting to the postcapillary venule.
  • Capillaries are the smallest blood vessels, often smaller than red blood cells, with a single layer of endothelial cells and basal lamina.
  • Capillaries have a single layer of endothelium for fluid exchange.
  • In many capillaries, the lumen is narrow, requiring red blood cells to fold for passage.
  • Pericytes, undifferentiated mesenchymal stem cells, are associated with capillaries.
  • Capillaries are classified as continuous, fenestrated, or discontinuous/sinusoidal, based on structural characteristics (e.g., openings, gaps).
  • Postcapillary venules are the smallest veins, with pericytes instead of a tunica media and more permeable walls than capillaries or venules. They are responsible for exchanging materials.
  • Some venules act as 'leaky' vessels due to vasodilator substances like serotonin and histamine increasing intercellular distances.
  • Leukocytes preferentially leave the vascular system at postcapillary venules, entering connective tissue spaces via diapedesis.
  • In certain tissues, arterioles bypass capillaries and connect directly to venules (arteriovenous shunts) to accommodate specialized functions such as thermoregulation.
  • Arteriovenous shunts have thicker media and adventitia layers and are richly innervated by sympathetic and parasympathetic nerve fibers.

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Explore the intricate structure of small blood vessels, including arterioles, capillaries, and venules. Understand their layers, functions, and roles in blood flow and material exchange. This quiz will test your knowledge on the key components and characteristics of these crucial vascular structures.

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