Structure-Function Relationship in Specific Proteins
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Structure-Function Relationship in Specific Proteins

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Questions and Answers

What is the primary function of myoglobin?

  • Act as an enzyme
  • Transport CO2 from tissues to lungs
  • Transport oxygen from the lung to the tissues
  • Muscle stores oxygen (correct)

    • Which type of proteins have a compact, globular structure and are water soluble?

  • Fibrous proteins
  • Globular proteins (correct)
  • Collagen
  • Myosin

    • What is the primary function of hemoglobin?

  • Transport oxygen from the lung to the tissues (correct)
  • Muscle stores oxygen
  • Transport CO2 from tissues to lungs
  • Act as a motor protein

    • What is the role of the heme group in myoglobin and hemoglobin?

    <p>Binds oxygen and protects iron from oxidation</p> Signup and view all the answers

    What is the main function of hemoglobin?

    <p>Transport gases through the blood</p> Signup and view all the answers

    What is the quaternary structure of hemoglobin?

    <p>Oligomeric protein with 4 polypeptide chains and 4 heme prosthetic groups</p> Signup and view all the answers

    What triggers the change in conformation of hemoglobin from T state to R state?

    <p>Binding of oxygen to a Hb subunit in the T state</p> Signup and view all the answers

    What effect do protons and CO2 have on hemoglobin's affinity for oxygen?

    <p>Reduce the affinity of Hb for oxygen</p> Signup and view all the answers

    What is the primary function of collagen?

    <p>Provide strength in connective tissues</p> Signup and view all the answers

    What is the secondary structure of collagen helix?

    <p>Left-handed helix with three amino acid residues per turn</p> Signup and view all the answers

    What disease is caused by a genetic disorder resulting in fragile bones that break easily?

    <p>Osteogenesis imperfecta</p> Signup and view all the answers

    What is required for the formation of hydroxyproline in collagen?

    <p>Vitamin C</p> Signup and view all the answers

    What are the subunits present in myosin?

    <p>2 heavy chains and 2 light chains</p> Signup and view all the answers

    What type of filament does actin polymerize to form?

    <p>F-actin (filamentous actin)</p> Signup and view all the answers

    Which type of proteins have a compact, globular structure and are water soluble?

    <p>Globular proteins</p> Signup and view all the answers

    What is the primary function of myoglobin?

    <p>Stores oxygen in muscle</p> Signup and view all the answers

    What is the quaternary structure of hemoglobin?

    <p>Consists of four subunits</p> Signup and view all the answers

    What is the role of the heme group in myoglobin and hemoglobin?

    <p>To protect iron from oxidation</p> Signup and view all the answers

    What triggers the change in conformation of hemoglobin from T state to R state?

    <p>$O_2$ concentration</p> Signup and view all the answers

    What is the main function of hemoglobin?

    <p>Transport oxygen from the lung to the tissues</p> Signup and view all the answers

    What is the quaternary structure of hemoglobin?

    <p>Oligomeric protein with 4 polypeptide chains and 4 heme prosthetic groups</p> Signup and view all the answers

    What is the main function of collagen?

    <p>Resistance to tension in skin, bone, tendon, and teeth</p> Signup and view all the answers

    What triggers the change in conformation of hemoglobin from T state to R state?

    <p>The binding of O2 to a Hb subunit in the T state</p> Signup and view all the answers

    What is required to form hydroxyproline in collagen?

    <p>$Vitamin C$</p> Signup and view all the answers

    What is the secondary structure of collagen helix?

    <p>$left-handed helix$</p> Signup and view all the answers

    What effect do protons and $CO_2$ have on hemoglobin's affinity for oxygen?

    <p>$Reduce the affinity of Hb for oxygen, leading to release of $O_2$ to the tissues$</p> Signup and view all the answers

    What disease is caused by a genetic disorder resulting in fragile bones that break easily?

    <p>Osteogenesis imperfecta</p> Signup and view all the answers

    What are the subunits present in myosin?

    <p>Two heavy chains and two light chains</p> Signup and view all the answers

    What type of filament does actin polymerize to form?

    <p>Thin filament (F-actin)</p> Signup and view all the answers

    What is the primary function of myoglobin?

    <p>Transport gases through the blood</p> Signup and view all the answers

    Which one of these describes the quaternary structure of hemoglobin?

    <p>An oligomeric protein with 4 polypeptide chains and 4 heme prosthetic groups</p> Signup and view all the answers

    Study Notes

    Protein Structure and Function

    • Globular proteins have a compact, globular structure and are water soluble.
    • Myoglobin and hemoglobin are examples of globular proteins.

    Myoglobin

    • The primary function of myoglobin is to store oxygen in muscles.
    • The heme group in myoglobin plays a crucial role in binding oxygen.

    Hemoglobin

    • The primary function of hemoglobin is to transport oxygen from lungs to tissues.
    • The quaternary structure of hemoglobin is a tetramer, consisting of two alpha and two beta subunits.
    • The heme group in hemoglobin plays a crucial role in binding oxygen.
    • The change in conformation of hemoglobin from T state to R state is triggered by the binding of oxygen.
    • The main function of hemoglobin is to transport oxygen from lungs to tissues.
    • Protons and CO2 decrease hemoglobin's affinity for oxygen.

    Collagen

    • The primary function of collagen is to provide structure and strength to connective tissue.
    • The secondary structure of collagen helix is a triple helix.
    • Hydroxyproline is required for the formation of collagen, and vitamin C is necessary for its formation.
    • Osteogenesis imperfecta is a disease caused by a genetic disorder resulting in fragile bones that break easily.

    Muscle Proteins

    • Myosin has two subunits: heavy chain and light chain.
    • Actin polymerizes to form microfilaments.

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    Structure-Function Relationship in Specific Proteins PDF

    Description

    Explore the structure-function relationship in specific proteins with this quiz, focusing on globular proteins like hemoglobin and myoglobin, and fibrous proteins such as collagen, myosin, and actin fibers.

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