Structure and Function of Microtubules: Intracellular Motility

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What is the main function of cytoplasmic dynein in a cell?

Control the number of microtubules in the centrosome

Regulate the polarity of microtubules in the cell

Facilitate the assembly of microtubules at the MTOC

Position the spindle and move chromosomes during mitosis (correct)

What is the subunit incorporated into a microtubule polymer?

ATP-actin monomers

GTP-αβ-tubulin heterodimer (correct)

70 different proteins as tetramers

ATPase

Which end of a microtubule is the preferential site of incorporation?

+ End (barbed)

+ End (β-tubulin) (correct)

Polarity

Internal

Which organelle or structure is positioned by cytoplasmic dynein?

Spindle Signup and view all the answers

What type of enzymatic activity is associated with microtubules?

GTPase Signup and view all the answers

What is the primary role of microtubule-organizing centers (MTOCs) in a cell?

Control the number of microtubules Signup and view all the answers

Which type of motor proteins are associated with microtubules?

Kinesins, dyneins Signup and view all the answers

Which statement accurately describes the function of centrosomes in a cell?

Nucleation of microtubules happens rapidly inside a cell, associated with MTOCs Signup and view all the answers

How do kinesins and dyneins differ in their roles within a cell?

Kinesins move organelles towards the cell periphery, while dyneins move organelles towards the cell center Signup and view all the answers

What is the structure of microtubules?

Stiff, hollow, inextensible tube Signup and view all the answers

Which group of proteins is a major companion of microtubules?

MAPs Signup and view all the answers

What is the main function of microtubules in nerve cells?

Enable directed movement to deliver essential material Signup and view all the answers

Which statement accurately describes the role of microtubules in intracellular motility?

Microtubules generate the forces required to move objects within a cell Signup and view all the answers

In nerve cells, why is directed movement along microtubules crucial?

To facilitate the delivery of neurotransmitters and essential material Signup and view all the answers

How do microtubules contribute to the organization of nerve cells?

By integrating with other cytoskeletal components for directed movement Signup and view all the answers

What are the consequences of defects in transport along microtubules?

Development of neurological diseases Signup and view all the answers