Structure and Function of Microtubules: Intracellular Motility
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Questions and Answers

What is the main function of cytoplasmic dynein in a cell?

  • Control the number of microtubules in the centrosome
  • Regulate the polarity of microtubules in the cell
  • Facilitate the assembly of microtubules at the MTOC
  • Position the spindle and move chromosomes during mitosis (correct)

What is the subunit incorporated into a microtubule polymer?

  • ATP-actin monomers
  • GTP-αβ-tubulin heterodimer (correct)
  • 70 different proteins as tetramers
  • ATPase

Which end of a microtubule is the preferential site of incorporation?

  • + End (barbed)
  • + End (β-tubulin) (correct)
  • Polarity
  • Internal

Which organelle or structure is positioned by cytoplasmic dynein?

<p>Spindle (B)</p> Signup and view all the answers

What type of enzymatic activity is associated with microtubules?

<p>GTPase (A)</p> Signup and view all the answers

What is the primary role of microtubule-organizing centers (MTOCs) in a cell?

<p>Control the number of microtubules (A)</p> Signup and view all the answers

Which type of motor proteins are associated with microtubules?

<p>Kinesins, dyneins (A)</p> Signup and view all the answers

Which statement accurately describes the function of centrosomes in a cell?

<p>Nucleation of microtubules happens rapidly inside a cell, associated with MTOCs (B)</p> Signup and view all the answers

How do kinesins and dyneins differ in their roles within a cell?

<p>Kinesins move organelles towards the cell periphery, while dyneins move organelles towards the cell center (B)</p> Signup and view all the answers

What is the structure of microtubules?

<p>Stiff, hollow, inextensible tube (A)</p> Signup and view all the answers

Which group of proteins is a major companion of microtubules?

<p>MAPs (D)</p> Signup and view all the answers

What is the main function of microtubules in nerve cells?

<p>Enable directed movement to deliver essential material (A)</p> Signup and view all the answers

Which statement accurately describes the role of microtubules in intracellular motility?

<p>Microtubules generate the forces required to move objects within a cell (B)</p> Signup and view all the answers

In nerve cells, why is directed movement along microtubules crucial?

<p>To facilitate the delivery of neurotransmitters and essential material (D)</p> Signup and view all the answers

How do microtubules contribute to the organization of nerve cells?

<p>By integrating with other cytoskeletal components for directed movement (B)</p> Signup and view all the answers

What are the consequences of defects in transport along microtubules?

<p>Development of neurological diseases (D)</p> Signup and view all the answers

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