Structure and Function of Microtubules: Intracellular Motility
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Questions and Answers

What is the main function of cytoplasmic dynein in a cell?

  • Control the number of microtubules in the centrosome
  • Regulate the polarity of microtubules in the cell
  • Facilitate the assembly of microtubules at the MTOC
  • Position the spindle and move chromosomes during mitosis (correct)

    • What is the subunit incorporated into a microtubule polymer?

  • ATP-actin monomers
  • GTP-αβ-tubulin heterodimer (correct)
  • 70 different proteins as tetramers
  • ATPase

    • Which end of a microtubule is the preferential site of incorporation?

  • + End (barbed)
  • + End (β-tubulin) (correct)
  • Polarity
  • Internal

    • Which organelle or structure is positioned by cytoplasmic dynein?

    <p>Spindle</p> Signup and view all the answers

    What type of enzymatic activity is associated with microtubules?

    <p>GTPase</p> Signup and view all the answers

    What is the primary role of microtubule-organizing centers (MTOCs) in a cell?

    <p>Control the number of microtubules</p> Signup and view all the answers

    Which type of motor proteins are associated with microtubules?

    <p>Kinesins, dyneins</p> Signup and view all the answers

    Which statement accurately describes the function of centrosomes in a cell?

    <p>Nucleation of microtubules happens rapidly inside a cell, associated with MTOCs</p> Signup and view all the answers

    How do kinesins and dyneins differ in their roles within a cell?

    <p>Kinesins move organelles towards the cell periphery, while dyneins move organelles towards the cell center</p> Signup and view all the answers

    What is the structure of microtubules?

    <p>Stiff, hollow, inextensible tube</p> Signup and view all the answers

    Which group of proteins is a major companion of microtubules?

    <p>MAPs</p> Signup and view all the answers

    What is the main function of microtubules in nerve cells?

    <p>Enable directed movement to deliver essential material</p> Signup and view all the answers

    Which statement accurately describes the role of microtubules in intracellular motility?

    <p>Microtubules generate the forces required to move objects within a cell</p> Signup and view all the answers

    In nerve cells, why is directed movement along microtubules crucial?

    <p>To facilitate the delivery of neurotransmitters and essential material</p> Signup and view all the answers

    How do microtubules contribute to the organization of nerve cells?

    <p>By integrating with other cytoskeletal components for directed movement</p> Signup and view all the answers

    What are the consequences of defects in transport along microtubules?

    <p>Development of neurological diseases</p> Signup and view all the answers

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