Structure and Function of DNA
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Questions and Answers

Which nitrogenous base pairs with adenine in DNA?

  • Uracil
  • Cytosine
  • Guanine
  • Thymine (correct)
  • The primary function of DNA replication is to create genetic diversity.

    False

    Who were the primary contributors to the discovery of the DNA double-helix model?

    James Watson and Francis Crick

    DNA is composed of two strands of __________ held together by hydrogen bonds.

    <p>nucleotides</p> Signup and view all the answers

    Match the following scientists with their contributions to the understanding of DNA:

    <p>James Watson = Proposed the double-helix model Francis Crick = Collaborated with Watson on DNA structure Rosalind Franklin = Provided X-ray diffraction data Maurice Wilkins = Assisted in sharing Franklin's data</p> Signup and view all the answers

    What is the cause of sickle cell anemia?

    <p>A change in hemoglobin structure due to a mutation.</p> Signup and view all the answers

    All mutations are harmful to organisms.

    <p>False</p> Signup and view all the answers

    What term is used to describe the observable traits of an organism?

    <p>Phenotype</p> Signup and view all the answers

    A person with two different alleles for a particular gene is described as _____.

    <p>heterozygous</p> Signup and view all the answers

    Match the following terms with their definitions:

    <p>Homozygous = An organism with two identical alleles for a gene Genotype = The genetic constitution of an organism Punnett Square = A tool to predict genetic combinations Pedigree = A diagram tracing trait inheritance through generations</p> Signup and view all the answers

    Study Notes

    Structure and Function of DNA

    • DNA, or deoxyribonucleic acid, has a double helix structure made of two nucleotide strands.
    • Each nucleotide consists of a deoxyribose sugar, phosphate group, and one of four nitrogenous bases: adenine (A), thymine (T), cytosine (C), and guanine (G).
    • Hydrogen bonds form between complementary bases (A with T, C with G), stabilizing the structure for genetic information storage.

    Contributions to the Double-Helix Model

    • James Watson and Francis Crick proposed the DNA double-helix model in 1953, using model building and various data sources, including X-ray diffraction.
    • Rosalind Franklin's X-ray diffraction images, notably "Photo 51," provided crucial evidence of DNA's helical structure.
    • Maurice Wilkins collaborated with Franklin and shared her findings with Watson and Crick, aiding in model development.

    Benefits and Limitations of Models in Science

    • Benefits include simplifying complex processes for better understanding and communication among scientists.
    • Models enable predictions of outcomes and testing of hypotheses in controlled environments.
    • Limitations involve potential oversimplification, which can omit critical variables, and misrepresentation that may lead to misconceptions.

    Role of DNA Replication

    • DNA replication occurs before cell division, duplicating DNA to ensure genetic continuity in daughter cells.
    • It is vital for providing each daughter cell with an accurate DNA copy to prevent mutations, which can cause diseases or developmental issues.
    • Proofreading mechanisms during replication help minimize errors, preserving genetic stability.

    Mutations and Their Causes

    • Mutations are changes in the DNA sequence and can arise from spontaneous errors during replication or external factors like radiation and chemicals.
    • They can be beneficial, neutral, or harmful, impacting an organism's phenotype and potentially resulting in genetic disorders.

    Sickle Cell Anemia and Mutation

    • Sickle cell anemia results from a mutation in the hemoglobin gene, where adenine (A) is swapped with thymine (T).
    • This single nucleotide alteration leads to abnormal hemoglobin (hemoglobin S), causing red blood cells to become rigid and take on a sickle shape, hindering blood flow and causing pain and organ damage.

    Genetic Terminology

    • Phenotype: Observable traits of an organism, shaped by genotype and environmental factors.
    • Genotype: Genetic makeup of an organism, indicating the alleles inherited from parents.
    • Homozygous: Organism with two identical alleles for a gene (e.g., AA or aa).
    • Heterozygous: Organism with two different alleles for a gene (e.g., Aa).

    Punnett Squares and Simple Inheritance

    • Punnett squares are tools used to predict offspring genotypes from parental allele combinations.
    • They visually represent possible allele combinations and help illustrate inheritance patterns.
    • Example: Crossing a homozygous dominant (AA) with a homozygous recessive (aa) yields all heterozygous (Aa) offspring displaying the dominant phenotype.

    Pedigrees

    • Pedigrees are family tree diagrams that illustrate the inheritance of traits across generations.
    • They use symbols to depict individuals and their relationships, aiding in the identification of inheritance patterns for specific traits or genetic conditions.
    • Analyzing pedigrees allows geneticists to predict traits likely to be passed down to future generations.

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    Description

    This quiz explores the structure and function of DNA, focusing on its double helix formation and the components of nucleotides. You'll learn about the roles of deoxyribose, phosphate groups, and nitrogenous bases in carrying genetic information. Test your knowledge on the complementary base pairing and the stability of the DNA structure.

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